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pro vyhledávání: ''
Autor:
Duong Thuy Tran, Stephanie K. Y. Choi, Kristian B. Filion, Clara K Chow, Alys Havard, Sallie-Anne Pearson
Publikováno v:
JAMA Network Open
Key Points Question What is the relative cardiovascular safety of the smoking cessation pharmacotherapies varenicline, nicotine replacement therapy (NRT) patches, and bupropion? Findings In this cohort study of 342 064 varenicline and 10 457 bupropio
Publikováno v:
JAMA Network Open
Importance Antiviral treatment of influenza is recommended for patients with influenza-like illness during periods of community cocirculation of influenza viruses and SARS-CoV-2; however, questions remain about which treatment is associated with the
Publikováno v:
JAMA Network Open. 4:e2110268
Importance Infusion reactions occur in 7% to 20% of patients receiving biologics. Home infusions are convenient and incur lower costs but may be associated with more adverse events; the safety of receiving biologic infusions for immune-mediated disea
Autor:
Jost Klawitter, Grace Wheeler, Jodi M. Gilman, Randi M. Schuster, A. Eden Evins, William A Schmitt, Cristina Sempio
Publikováno v:
JAMA Network Open
Among adults using medical cannabis frequently and recently, THC and CBD metabolite concentrations in urine often differed from expected exposure. Approximately one-third of samples from people reporting using CBD-dominant products contained no measu
Publikováno v:
JAMA. 322:868
Importance Medications to reduce risk of breast cancer are effective for women at increased risk but also cause adverse effects. Objective To update the 2013 US Preventive Services Task Force systematic review on medications to reduce risk of primary
Autor:
Pierre Serusclat, Julio Rosenstock, Hirotaka Watada, Dale Allison, Thalia Marie Blicher, Jacob Bonde Jacobsen, Rafael Violante, Andreas L. Birkenfeld, Srikanth Deenadayalan, Melanie J. Davies
Publikováno v:
JAMA 321, 1466-1480 (2019)
IMPORTANCE: Phase 3 trials have not compared oral semaglutide, a glucagon-like peptide 1 receptor agonist, with other classes of glucose-lowering therapy. OBJECTIVE: To compare efficacy and assess long-term adverse event profiles of once-daily oral s
Autor:
Andrea M. Austin, Gabriel A. Brooks, Anna N. A. Tosteson, Deborah Schrag, Hajime Uno, Konstantin H. Dragnev
Publikováno v:
JAMA Network Open
Key Points Question Does the risk of hospitalization among elderly patients receiving chemotherapy for metastatic, nonsquamous, non–small cell lung cancer vary by chemotherapy regimen? Findings In a cohort study of 2182 propensity-matched Medicare
Autor:
Paul M. Cinciripini, F. Joseph McClernon, Scott J. Leischow, Lori S Strayer, Tonya Lane, Menglan Chen, Ryan Vandrey, David J. Drobes, Mustafa al'Absi, Neal L. Benowitz, Xianghua Luo, Rachel L Denlinger-Apte, Christopher J. Sipe, Viviana Paiano, Chap T. Le, Sharon E. Murphy, Mei Kuen Tang, Jason D. Robinson, Kai Luo, Sharon S Allen, Eric C. Donny, Joni Jensen, Herbert H. Severson, Stephen S. Hecht, Andrew A. Strasser, Dorothy K. Hatsukami, Joseph S. Koopmeiners, Steven G. Carmella
Publikováno v:
JAMA. 320:880
IMPORTANCE: The optimal temporal approach for reducing nicotine to minimally or nonaddictive levels in all cigarettes sold in the United States has not been determined. OBJECTIVES: To determine the effects of immediate vs gradual reduction in nicotin
Autor:
Mark Feldman
Publikováno v:
JAMA: The Journal of the American Medical Association. 275:1428-1431
Objective. —To compare an over-the-counter histamine2-receptor antagonist with an antacid as gastric acid reducers. Design. —Randomized, double-blind, placebo-controlled crossover trial. Setting. —Gastric secretory research laboratory in a Vete