Zobrazeno 1 - 10
of 16
pro vyhledávání: '"59"'
Autor:
Donna Buono, Marilyn L. Kwan, Laura Falci, Marion M. Lee, Alfred I. Neugut, Lois Lamerato, Dawn L. Hershman, Isaac J. Ergas, Jeanne S. Mandelblatt, Heather Greenlee, Grace Clarke Hillyer, Janise M. Roh, Wei-Yann Tsai, Zaixing Shi, Lawrence H. Kushi
Publikováno v:
JAMA Oncology. 2:1170
Importance Not all women initiate clinically indicated breast cancer adjuvant treatment. It is important for clinicians to identify women at risk for noninitiation. Objective To determine whether complementary and alternative medicine (CAM) use is as
Autor:
C. Griffin, Pasi A. Jänne, S. Jin, Veronica Bunn, Danny Nguyen, Gregory J. Riely, Tarek Mekhail, Tae Min Kim, M. Mehta, Sang-We Kim, Suresh S. Ramalingam, Caicun Zhou, Maria Rosario Garcia Campelo, Sylvie Vincent, Huamao M. Lin, Jianchang Lin, Enriqueta Felip, James Chih-Hsin Yang
Publikováno v:
JAMA Oncology. 7:e214761
Importance Metastatic non–small cell lung cancer (mNSCLC) withEGFRexon 20 insertion (EGFRex20ins) mutations is associated with a poor prognosis. Mobocertinib is an oral tyrosine kinase inhibitor designed to selectively targetEGFRex20ins mutations.
Autor:
Martin E. Gleave, David A. Quigley, Martin Sjöström, Kyle T Helzer, Nicholas R. Rydzewski, Marc D. Perry, Joshua M. Lang, Menggang Yu, Jiaoti Huang, Felix Y. Feng, S. Laura Chang, Eric J. Small, Won Kim, Christopher P. Evans, Li Zhang, Joshi J. Alumkal, Shuang G. Zhao, Rahul Aggarwal, Hamza Bakhtiar, Robert E. Reiter, Adam Foye
Publikováno v:
JAMA Oncol
IMPORTANCE: Luminal and basal subtypes of primary prostate cancer have been shown to be molecularly distinct and clinically important in predicting response to therapy. These subtypes have not been described in metastatic prostate cancer. OBJECTIVES:
Autor:
Nelly Mugo, Evans Nyongesa-Malava, Samah R. Sakr, Hugo De Vuyst, Anthony Cagle, Marleen Temmerman, Michael H. Chung, Christine J. McGrath, Elizabeth R. Unger, Stanley Luchters, Troy D. Querec, Sharon A Greene
Publikováno v:
JAMA Oncol
IMPORTANCE: Persistence of cervical high-risk human papillomavirus (hrHPV) after treatment for cervical intraepithelial neoplasia grade 2 or higher (CIN2+) has not been compared between cryotherapy and loop electrosurgical excision procedure (LEEP) a
Autor:
Marsha Reyngold, Megan Fiasconaro, Kenneth H. Yu, Abraham J. Wu, M. Zinovoy, Danny N. Khalil, Wungki Park, Lara Hilal, Zhigang Zhang, R. Tuli, Carla Hajj, Paul B. Romesser, John J. Cuaron, Anna M. Varghese, Ellen Yorke, Christopher H. Crane, Eileen M. O'Reilly
Publikováno v:
JAMA Oncol
Importance Surgical resection has been considered the only curative option for patients with pancreatic cancer. Nonoperative local treatment options that can provide a similar benefit are needed. Emerging radiation techniques that address organ motio
Autor:
Heather Cibotti, Katherine Van Loon, Andrea J. Bullock, Deborah Schrag, Hanna K. Sanoff, Andrea C. Enzinger, Janet Bagley, Elizabeth Frank, Christine Cronin, Hajime Uno, Nadine Jackson McCleary, Khalid Matin
Publikováno v:
JAMA Oncol
Importance Despite requirements of informed consent, patients with advanced cancer often receive palliative chemotherapy (PC) without understanding that the likelihood of cure is remote. Objective To determine whether a PC educational video and bookl
Autor:
Bruce Colwell, John R. Goffin, Hagen F. Kennecke, B. Samson, Félix Couture, Setareh Samimi, Tahir Abbas, Francine Aubin, Scott R. Berry, Alice C. Wei, Dongsheng Tu, Sheryl Koski, Nadine M Magoski, Petr Kavan, Chaudhary E. Ahmad, Jonathan M. Loree, Mohammed Harb, Christopher J. O'Callaghan, Nathalie Aucoin, Eric Chen, Derek J. Jonker
Publikováno v:
JAMA Oncology. 6:831
Single-agent immune checkpoint inhibition has not shown activities in advanced refractory colorectal cancer (CRC), other than in those patients who are microsatellite-instability high (MSI-H).To evaluate whether combining programmed death-ligand 1 (P
Autor:
Naveed Sarwar, Olivia Hatcher, Cathryn S Brock, Danielle Power, Alison Falconer, Heather Urus, Dorothy Gujral, Mark Bower, Sarah Howlett, Maggie Bendle, Michael Gonzalez, Conrad R. Lewanski, David J. Pinato, Takashi Mineo, Diego Ottaviani, Aisha Patel, Thomas Newsom-Davis, Sarah Partridge, Manasi Ingle, Elias Allara, Anna Brown
Publikováno v:
JAMA Oncology. 5:1774
Importance Gut dysbiosis impairs response to immune checkpoint inhibitors (ICIs) and can be caused by broad-spectrum antibiotic (ATB) therapy. Objective To evaluate whether there is an association between ATB therapy administered concurrently (cATB)
Autor:
Geoff Neuner, Amit Agrawal, Amanda L. Blackford, Maura L. Gillison, Bo Jiang, Weihong Xiao, Carole Fakhry
Publikováno v:
JAMA Oncol
IMPORTANCE: Detection of persistent oral human papillomavirus (HPV) DNA may be associated with recurrence of HPV-positive head and neck squamous cell carcinoma (HNSCC). OBJECTIVE: To evaluate the dynamics of oral HPV DNA detection and associations wi
Autor:
Serge Koscielny, L. Leroy, Jean-Charles Soria, Roberto Ferrara, Solenn Brosseau, Stéphane Champiat, Julien Mazieres, Caroline Caramella, Anas Gazzah, Sylvestre Le Moulec, Benjamin Besse, Julien Adam, Jordi Remon, Laurent Tessonnier, Charles Ferté, David Planchard, Clarisse Audigier-Valette, Corentin Lefebvre, J. Lahmar, Boris Duchemann, Laura Mezquita, Giampaolo Tortora, Marie Eve Boucher, Gérard Zalcman, Emilio Bria, Remi Veillon, M. Texier, Virginie Westeel
Publikováno v:
JAMA Oncology. 4:1543
Importance Hyperprogressive disease (HPD) is a new pattern of progression recently described in patients with cancer treated with programmed cell death 1 (PD-1) and programmed cell death ligand 1 (PD-L1) inhibitors. The rate and outcome of HPD in adv