Zobrazeno 1 - 10
of 19
pro vyhledávání: ''
Autor:
Børge G. Nordestgaard, Ruth Frikke-Schmidt, M. Christoffersen, Anne Tybjærg-Hansen, Bo K Lauridsen, Liv Tybjærg Nordestgaard, Shoaib Afzal
Publikováno v:
JAMA Cardiol
Importance The balance between the potential long-term clinical benefits and harms associated with genetic cholesteryl ester transfer protein (CETP) deficiency, mimicking pharmacologic CETP inhibition, is unknown. Objective To assess the relative ben
Autor:
Burgess, Stephen, Ference, Brian A., Staley, James R., Freitag, Daniel F., Mason, Amy M., Nielsen, Sune F., Willeit, Peter, Young, Robin, Surendran, Praveen, Karthikeyan, Savita, Bolton, Thomas R., Peters, James E., Kamstrup, Pia, Tybjærg-Hansen, Anne, Benn, Marianne, Langsted, Anne, Schnohr, Peter, Vedel-Krogh, Signe, Kobylecki, Camilla J., Ford, Ian, Packard, Chris, Trompet, Stella, Jukema, J. Wouter, Sattar, Naveed, Di Angelantonio, Emanuele, Saleheen, Danish, Howson, Joanna M.M., Nordestgaard, Børge G., Butterworth, Adam S., Danesh, John, Bargess, Stephen, Overvad, Kim, Tjønneland, Anne, Clavel-Chapelon, Francoise, Kaaks, Rudolf, Boeing, Heiner, Trichopoulou, Antonia, Ferrari, Pietro, Palli, Domenico, Krogh, Vittorio, Panico, Salvatore, Tumino, Rosario, Matullo, Giuseppe, Boer, Jolanda, Van Der Schouw, Yvonne, Weiderpass, Elisabete, Quiros, J. Ramon, Sánchez, María José, Navarro, Carmen, Moreno-Iribas, Conchi, Arriola, Larraitz, Melander, Olle, Wennberg, Patrik, Wareham, Nicholas J., Key, Timothy J., Riboli, Elio
Publikováno v:
JAMA Cardiology, 3(7), 619. American Medical Association
Burgess, S, Ference, B A, Staley, J R, Freitag, D F, Mason, A M, Nielsen, S F, Willeit, P, Young, R, Surendran, P, Karthikeyan, S, Bolton, T R, Peters, J E, Kamstrup, P, Tybjærg-Hansen, A, Benn, M, Langsted, A, Schnohr, P, Vedel-Krogh, S, Kobylecki, C J, Ford, I, Packard, C, Trompet, S, Jukema, J W, Sattar, N, Di Angelantonio, E, Saleheen, D, Howson, J M M, Nordestgaard, B G, Butterworth, A S, Danesh, J, European Prospective Investigation Into Cancer and Nutrition–Cardiovascular Disease (EPIC-CVD) Consortium & Overvad, K 2018, ' Association of LPA variants with risk of coronary disease and the implications for lipoprotein(a)-lowering therapies : A mendelian randomization analysis ', JAMA cardiology, vol. 3, no. 7, pp. 619-627 . https://doi.org/10.1001/jamacardio.2018.1470
JAMA Cardiology, 3(7), 619-627
Burgess, S, Ference, B A, Staley, J R, Freitag, D F, Mason, A M, Nielsen, S F, Willeit, P, Young, R, Surendran, P, Karthikeyan, S, Bolton, T R, Peters, J E, Kamstrup, P R, Tybjærg-Hansen, A, Benn, M, Langsted, A, Schnohr, P, Vedel-Krogh, S, Kobylecki, C J, Ford, I, Packard, C, Trompet, S, Jukema, J W, Sattar, N, Di Angelantonio, E, Saleheen, D, Howson, J M M, Nordestgaard, B G, Butterworth, A S, Danesh, J 2018, ' Association of LPA Variants With Risk of Coronary Disease and the Implications for Lipoprotein(a)-Lowering Therapies : A Mendelian Randomization Analysis ', JAMA Cardiology, vol. 3, no. 7, pp. 619-627 . https://doi.org/10.1001/jamacardio.2018.1470
Burgess, S, Ference, B A, Staley, J R, Freitag, D F, Mason, A M, Nielsen, S F, Willeit, P, Young, R, Surendran, P, Karthikeyan, S, Bolton, T R, Peters, J E, Kamstrup, P, Tybjærg-Hansen, A, Benn, M, Langsted, A, Schnohr, P, Vedel-Krogh, S, Kobylecki, C J, Ford, I, Packard, C, Trompet, S, Jukema, J W, Sattar, N, Di Angelantonio, E, Saleheen, D, Howson, J M M, Nordestgaard, B G, Butterworth, A S, Danesh, J, European Prospective Investigation Into Cancer and Nutrition–Cardiovascular Disease (EPIC-CVD) Consortium & Overvad, K 2018, ' Association of LPA variants with risk of coronary disease and the implications for lipoprotein(a)-lowering therapies : A mendelian randomization analysis ', JAMA cardiology, vol. 3, no. 7, pp. 619-627 . https://doi.org/10.1001/jamacardio.2018.1470
JAMA Cardiology, 3(7), 619-627
Burgess, S, Ference, B A, Staley, J R, Freitag, D F, Mason, A M, Nielsen, S F, Willeit, P, Young, R, Surendran, P, Karthikeyan, S, Bolton, T R, Peters, J E, Kamstrup, P R, Tybjærg-Hansen, A, Benn, M, Langsted, A, Schnohr, P, Vedel-Krogh, S, Kobylecki, C J, Ford, I, Packard, C, Trompet, S, Jukema, J W, Sattar, N, Di Angelantonio, E, Saleheen, D, Howson, J M M, Nordestgaard, B G, Butterworth, A S, Danesh, J 2018, ' Association of LPA Variants With Risk of Coronary Disease and the Implications for Lipoprotein(a)-Lowering Therapies : A Mendelian Randomization Analysis ', JAMA Cardiology, vol. 3, no. 7, pp. 619-627 . https://doi.org/10.1001/jamacardio.2018.1470
Importance: Human genetic studies have indicated that plasma lipoprotein(a) (Lp[a]) is causally associated with the risk of coronary heart disease (CHD), but randomized trials of several therapies that reduce Lp(a) levels by 25% to 35% have not provi
Autor:
Di Angelantonio, Emanuele, Gao, Pei, Khan, Hassan, Butterworth, Adam S., Wormser, David, Kaptoge, Stephen, Seshasai, Sreenivasa Rao Kondapally, Thompson, Alex, Sarwar, Nadeem, Willeit, Peter, Ridker, Paul M., Barr, Elizabeth L. M., Khaw, Kay-Tee, Psaty, Bruce M., Brenner, Hermann, Balkau, Beverley, Dekker, Jacqueline M., Lawlor, Debbie A., Daimon, Makoto, Willeit, Johann, Njolstad, Inger, Nissinen, Aulikki, Brunner, Eric J., Kuller, Lewis H., Price, Jackie F., Sundstrom, Johan, Knuiman, Matthew W., Feskens, Edith J. M., Verschuren, W. M. M., Wald, Nicholas, Bakker, Stephan J. L., Whincup, Peter H., Ford, Ian, Goldbourt, Uri, Gomez-de-la-Camara, Agustin, Gallacher, John, Simons, Leon A., Rosengren, Annika, Sutherland, Susan E., Bjorkelund, Cecilia, Blazer, Dan G., Wassertheil-Smoller, Sylvia, Onat, Altan, Ibanez, Alejandro Marin, Casiglia, Edoardo, Jukema, J. Wouter, Simpson, Lara M., Giampaoli, Simona, Nordestgaard, Borge G., Selmer, Randi, Wennberg, Patrik, Kauhanen, Jussi, Salonen, Jukka T., Dankner, Rachel, Barrett-Connor, Elizabeth, Kavousi, Maryam, Gudnason, Vilmundur, Evans, Denis, Wallace, Robert B., Cushman, Mary, D'Agostino, Ralph B., Sr., Umans, Jason G., Kiyohara, Yutaka, Nakagawa, Hidaeki, Sato, Shinichi, Gillum, Richard F., Folsom, Aaron R., van der Schouw, Yvonne T., Moons, Karel G., Griffin, Simon J., Sattar, Naveed, Wareham, Nicholas J., Selvin, Elizabeth, Thompson, Simon G., Emerging Risk Factors Collaboration, Stehouwer, Coen, Danesh, John
Publikováno v:
JAMA-Journal of the American Medical Association, 311(12), 1225-1233. AMER MEDICAL ASSOC
JAMA: The Journal of the American Medical Association 311 (2014) 12
JAMA-Journal of the American Medical Association, 311(12), 1225-1233. American Medical Association
JAMA, 311(12), 1225-1233. American Medical Association
Journal of the American Medical Association, 311(12), 1225-1233
Di Angelantonio, E, Gao, P, Khan, H, Butterworth, A S, Wormser, D, Kaptoge, S, Seshasai, S R K, Thompson, A, Sarwar, N, Willeit, P, Ridker, P M, Barr, E L M, Khaw, K T, Psaty, B M, Brenner, H, Balkau, B, Dekker, J M, Lawlor, D A, Daimon, M, Willeit, J, Njolstad, I, Nissinen, A, Brunner, E J, Kuller, L H, Price, J F, Sundstrom, J, Knuiman, M W, Feskens, E J M, Verschuren, W M M, Wald, N, Bakker, S J L, Whincup, P H, Ford, I, Goldbourt, U, Gomez-de-la-Camara, A, Gallacher, J, Simons, L A, Rosengren, A, Sutherland, S E, Bjorkelund, C, Blazer, D G, Wassertheil-Smoller, S, Onat, A, Ibanez, A M, Casiglia, E, Jukema, J W, Simpson, L M, Giampaoli, S, Nordestgaard, B G, Selmer, R, Wennberg, P, Kauhanen, J, Salonen, J T, Dankner, R, Barrett-Connor, E, Kavousi, M, Gudnason, V, Evans, D, Wallace, R B, Cushman, M, D'Agostino, R B, Umans, J G, Kiyohara, Y, Nakagawa, H, Sato, S, Gillum, R F, Folsom, A R, van der Schouw, Y T, Moons, K G, Griffin, S J, Sattar, N, Wareham, N J, Selvin, E, Thompson, S G & Danesh, J 2014, ' Glycated Hemoglobin Measurement and Prediction of Cardiovascular Disease ', JAMA, vol. 311, no. 12, pp. 1225-1233 . https://doi.org/10.1001/jama.2014.1873
JAMA: The Journal of the American Medical Association, 311(12), 1225-1233
JAMA: The Journal of the American Medical Association 311 (2014) 12
JAMA-Journal of the American Medical Association, 311(12), 1225-1233. American Medical Association
JAMA, 311(12), 1225-1233. American Medical Association
Journal of the American Medical Association, 311(12), 1225-1233
Di Angelantonio, E, Gao, P, Khan, H, Butterworth, A S, Wormser, D, Kaptoge, S, Seshasai, S R K, Thompson, A, Sarwar, N, Willeit, P, Ridker, P M, Barr, E L M, Khaw, K T, Psaty, B M, Brenner, H, Balkau, B, Dekker, J M, Lawlor, D A, Daimon, M, Willeit, J, Njolstad, I, Nissinen, A, Brunner, E J, Kuller, L H, Price, J F, Sundstrom, J, Knuiman, M W, Feskens, E J M, Verschuren, W M M, Wald, N, Bakker, S J L, Whincup, P H, Ford, I, Goldbourt, U, Gomez-de-la-Camara, A, Gallacher, J, Simons, L A, Rosengren, A, Sutherland, S E, Bjorkelund, C, Blazer, D G, Wassertheil-Smoller, S, Onat, A, Ibanez, A M, Casiglia, E, Jukema, J W, Simpson, L M, Giampaoli, S, Nordestgaard, B G, Selmer, R, Wennberg, P, Kauhanen, J, Salonen, J T, Dankner, R, Barrett-Connor, E, Kavousi, M, Gudnason, V, Evans, D, Wallace, R B, Cushman, M, D'Agostino, R B, Umans, J G, Kiyohara, Y, Nakagawa, H, Sato, S, Gillum, R F, Folsom, A R, van der Schouw, Y T, Moons, K G, Griffin, S J, Sattar, N, Wareham, N J, Selvin, E, Thompson, S G & Danesh, J 2014, ' Glycated Hemoglobin Measurement and Prediction of Cardiovascular Disease ', JAMA, vol. 311, no. 12, pp. 1225-1233 . https://doi.org/10.1001/jama.2014.1873
JAMA: The Journal of the American Medical Association, 311(12), 1225-1233
IMPORTANCE The value of measuring levels of glycated hemoglobin (HbA(1c)) for the prediction of first cardiovascular events is uncertain. OBJECTIVE To determine whether adding information on HbA(1c) values to conventional cardiovascular risk factors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::825869dccc06a4aaecd8615973474c13
https://www.repository.cam.ac.uk/handle/1810/353880
https://www.repository.cam.ac.uk/handle/1810/353880
Publikováno v:
JAMA, 313(10), 1029-1036. American Medical Association
IMPORTANCE Familial hypercholesterolemia is characterized by impaired uptake of cholesterol in peripheral tissues, including the liver and the pancreas. In contrast, statins increase the cellular cholesterol uptake and are associated with increased r
Autor:
Ralph B. D'Agostino, Judith R. McNamara, Peter W.F. Wilson, Michael J. Pencina, John H. Contois, Christopher Schoonmaker, Michelle J. Keyes, Lisa M. Sullivan, Ramachandran S. Vasan, Erik Ingelsson, Ernst J. Schaefer
Publikováno v:
JAMA. 298:776
ContextEvidence is conflicting regarding the performance of apolipoproteins vs traditional lipids for predicting coronary heart disease (CHD) risk.ObjectivesTo compare performance of different lipid measures for CHD prediction using discrimination an
Autor:
E. Murat Tuzcu, Samir R. Kapadia, Paul Schoenhagen, Kathy Wolski, Stanley L. Hazen, Adam W. Grasso, Milind Y. Desai, Ilke Sipahi, Tim Crowe, Stephen J. Nicholls, Steven E. Nissen, Tingfei Hu
Publikováno v:
JAMA. 297:499
ContextStatins reduce low-density lipoprotein cholesterol (LDL-C) levels and slow progression of coronary atherosclerosis. However, no data exist describing the relationship between statin-induced changes in high-density lipoprotein cholesterol (HDL-
Autor:
M. Sciacco, Costanza Lamperti, Alessandro Prelle, Petra Kaufmann, Valeria Lucchini, Salvatore DiMauro, Ali Naini, Maurizio Moggio, Nereo Bresolin
Publikováno v:
Archives of Neurology. 62:1709
Background Statin drugs (3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors) reduce the level of cholesterol by inhibiting the synthesis of mevalonate, an intermediary in the cholesterol biosynthetic pathway. Use of statin drugs has been asso
Autor:
Steven E. Nissen, E. Murat Tuzcu, Paul Schoenhagen, B. Greg Brown, Peter Ganz, Robert A. Vogel, Tim Crowe, Gail Howard, Christopher J. Cooper, Bruce Brodie, Cindy L. Grines, Anthony N. DeMaria, null for the REVERSAL Investigators
Publikováno v:
JAMA. 291:1071
ContextStatin drugs reduce both atherogenic lipoproteins and cardiovascular morbidity and mortality. However, the optimal strategy and target level for lipid reduction remain uncertain.ObjectiveTo compare the effect of regimens designed to produce in
Autor:
Eugeen Vanmechelen, Olov Wiklund, Hugo Vanderstichele, Kina Höglund, Oliver Eikenberg, Kaj Blennow
Publikováno v:
Archives of Neurology. 61:333
Background Epidemiological studies suggest that statins reduce the risk of developing Alzheimer disease. Cell and animal experiments have revealed a connection between cholesterol metabolism and the processing of amyloid precursor protein. To our kno
Publikováno v:
Archives of Ophthalmology. 121:1269
Background In a 4-year placebo-controlled trial to elevate blood docosahexaenoic acid levels in patients with X-linked retinitis pigmentosa (XLRP), the goal was to assess the potential benefit of docosahexaenoic acid supplementation in altering disea