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Publikováno v:
JAMA Dermatol
IMPORTANCE: Up to 90% of patients treated with an epidermal growth factor receptor inhibitor (EGFRi) experience cutaneous toxic effects that are negatively associated with quality of life and lead to treatment interruptions. The Skin Toxicity Evaluat
Publikováno v:
JAMA Dermatol
Importance Our understanding of potential racial/ethnic, sex, and other differences in health care use and treatment for acne is limited. Objective To identify potential disparities in acne care by evaluating factors associated with health care use a
Publikováno v:
JAMA Otolaryngol Head Neck Surg
Importance Clinicians frequently use radiotherapy with cetuximab over radiotherapy only or radiotherapy with cisplatin because of a perceived survival and tolerability advantage, but scant data are available to support this perception. Objective To m
Autor:
Lauren D. Murphy, Ying Zhang, Jacquelyn A. Quin, Jennifer Myers, Devan Kansagara, Barbara J. Homoya, Jessica Coffing, Anthony J. Perkins, Kathryn Snow, Laura J. Myers, Dawn M. Bravata
Publikováno v:
JAMA Surgery. 154:e184679
Importance The recommendations about antithrombotic medication use after bioprosthetic aortic valve replacement (bAVR) vary. Objectives To describe the post-bAVR antithrombotic medication practice across the Veterans Health Administration (VHA) and t
Autor:
Robert C. Smallridge, Ana Maria Chindris, Electron Kebebew, Athanasios Bikas, Brianna Daley, Leonard Wartofsky, Kenneth D. Burman, Eliza Dewey, Sungyoung Auh, Joanna Klubo-Gwiezdzinska, Marvin C. Gershengorn, Mark L. Urken
Publikováno v:
JAMA Network Open
Key Points Question Is thyrotropin suppression associated with better outcomes in patients with intermediate- and high-risk differentiated thyroid cancer? Findings In this cohort study including 867 patients with intermediate- and high-risk different
Autor:
Brandon Hood, Huiyong T Zheng, Brian R. Hallstrom, Mark E. Cowen, Bonita Singal, R. E. Hughes
Publikováno v:
JAMA Surgery. 154:65
IMPORTANCE: There has been significant debate in the surgical and medical communities regarding the appropriateness of using aspirin alone for venous thromboembolism (VTE) prophylaxis following total knee arthroplasty (TKA). OBJECTIVE: To determine t
Autor:
Andrea M. Austin, Gabriel A. Brooks, Anna N. A. Tosteson, Deborah Schrag, Hajime Uno, Konstantin H. Dragnev
Publikováno v:
JAMA Network Open
Key Points Question Does the risk of hospitalization among elderly patients receiving chemotherapy for metastatic, nonsquamous, non–small cell lung cancer vary by chemotherapy regimen? Findings In a cohort study of 2182 propensity-matched Medicare
Autor:
Andrew L. Masica, An T. Pham, Gerald O. Ogola, Natalie Mears, Maria Kouznetsova, Ashley W. Collinsworth, Laurel A. Copeland, Taoran Qiu, I-Chia Liao, Shahid Shafi, George J. Wan
Publikováno v:
JAMA Surgery. 153:757
IMPORTANCE: Opioids are commonly used for pain control during and after invasive procedures. However, opioid-related adverse drug events (ORADEs) are common and have been associated with worse patient outcomes. OBJECTIVES: To examine the incidence of
Autor:
Devika Gajria, Donald Chan, Azael Freites-Martinez, Shari Goldfarb, Stephen W. Dusza, Jerry Shapiro, Monica Fornier, Shanu Modi, Mario E. Lacouture
Publikováno v:
JAMA Dermatology. 154:670
IMPORTANCE: Endocrine therapy-induced alopecia (EIA) has been anecdotally reported but not systematically described. OBJECTIVE: To characterize EIA in patients with breast cancer. DESIGN, SETTING, AND PARTICIPANTS: Retrospective cohort study of 112 p
Publikováno v:
JAMA Otolaryngology–Head & Neck Surgery. 144:203
Importance Endoscopic dilation is the mainstay treatment strategy for subglottic and proximal tracheal stenosis (SGS/PTS). Its major limitation is restenosis requiring repeated surgery. Intralesional steroid injection (ISI) is a promising adjunctive