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pro vyhledávání: '"Willems SM"'
Autor:
Lotta, LA, Sharp, SJ, Burgess, S, Perry, JRB, Stewart, ID, Willems, SM, Luan, J, Ardanaz, E, Arriola, L, Balkau, B, Boeing, H, Deloukas, P, Forouhi, NG, Franks, PW, Grioni, S, Kaaks, R, Key, TJ, Navarro, C, Nilsson, PM, Overvad, K, Palli, D, Panico, S, Quirós, J-R, Riboli, E, Rolandsson, O, Sacerdote, C, Salamanca-Fernandez, E, Slimani, N, Spijkerman, AMW, Tjonneland, A, Tumino, R, Van Der A, DL, Van Der Schouw, YT, McCarthy, MI, Barroso, I, O'Rahilly, S, Savage, DB, Sattar, N, Langenberg, C, Scott, RA, Wareham, NJ
IMPORTANCE: Low-density lipoprotein cholesterol (LDL-C)-lowering alleles in or near $\textit{NPC1L1}$ or $\textit{HMGCR}$, encoding the respective molecular targets of ezetimibe and statins, have previously been used as proxies to study the efficacy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e74a0256d57f4e21a881623df327f802
Autor:
Lotta LA; MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom., Sharp SJ; MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom., Burgess S; Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom., Perry JRB; MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom., Stewart ID; MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom., Willems SM; MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom., Luan J; MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom., Ardanaz E; Navarre Public Health Institute (ISPN), Pamplona, Spain.; Navarra Institute for Health Research (IdiSNA) Pamplona, Spain.; CIBER Epidemiología y Salud Pública (CIBERESP), Spain., Arriola L; CIBER Epidemiología y Salud Pública (CIBERESP), Spain.; Public Health Division of Gipuzkoa, San Sebastian, Spain.; Instituto BIO-Donostia, Basque Government, San Sebastian, Spain., Balkau B; Inserm, CESP, U1018, Villejuif, France.; Inserm, CESP, U1018, Villejuif, France., Boeing H; German Institute of Human Nutrition Potsdam-Rehbruecke, Germany., Deloukas P; The Wellcome Trust Sanger Institute, Cambridge, United Kingdom., Forouhi NG; MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom., Franks PW; Lund University, Malmö, Sweden.; Umeå University, Umeå, Sweden., Grioni S; Epidemiology and Prevention Unit, Milan, Italy., Kaaks R; German Cancer Research Centre (DKFZ), Heidelberg, Germany., Key TJ; University of Oxford, Oxford, United Kingdom., Navarro C; CIBER Epidemiología y Salud Pública (CIBERESP), Spain.; Department of Epidemiology, Murcia Regional Health Council, IMIB-Arrixaca, Murcia, Spain.; Unit of Preventive Medicine and Public Health, School of Medicine, University of Murcia, Spain., Nilsson PM; Lund University, Malmö, Sweden., Overvad K; Department of Public Health, Section for Epidemiology, Aarhus University, Aarhus, Denmark.; Aalborg University Hospital, Aalborg, Denmark., Palli D; Cancer Research and Prevention Institute (ISPO), Florence, Italy., Panico S; Dipartimento di Medicina Clinica e Chirurgia, Federico II University, Naples, Italy., Quirós JR; Public Health Directorate, Asturias, Spain., Riboli E; School of Public Health, Imperial College London, United Kingdom., Rolandsson O; Umeå University, Umeå, Sweden., Sacerdote C; Unit of Cancer Epidemiology, Citta' della Salute e della Scienza Hospital-University of Turin and Center for Cancer Prevention (CPO), Torino, Italy.; Human Genetics Foundation (HuGeF), Torino, Italy., Salamanca EC; CIBER Epidemiología y Salud Pública (CIBERESP), Spain.; Andalusian School of Public Health, Granada, Spain.; Instituto de Investigación Biosanitaria de Granada (Granada.ibs), Granada, Spain., Slimani N; International Agency for Research on Cancer, Lyon, France., Spijkerman AM; National Institute for Public Health and the Environment (RIVM), Bilthoven, Netherlands., Tjonneland A; Danish Cancer Society Research Center, Copenhagen, Denmark., Tumino R; ASP Ragusa, Italy., van der A DL; National Institute for Public Health and the Environment (RIVM), Bilthoven, Netherlands., van der Schouw YT; University Medical Center Utrecht, Utrecht, the Netherlands., McCarthy MI; Oxford Centre for Diabetes, Endocrinology and Metabolism, and Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, United Kingdom., Barroso I; The Wellcome Trust Sanger Institute, Cambridge, United Kingdom., O'Rahilly S; Metabolic Research Laboratories, Institute of Metabolic Science, University of Cambridge, Cambridge, CB2 0QQ, United Kingdom., Savage DB; Metabolic Research Laboratories, Institute of Metabolic Science, University of Cambridge, Cambridge, CB2 0QQ, United Kingdom., Sattar N; Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, G12 8TA, United Kingdom., Langenberg C; MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom., Scott RA; MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom., Wareham NJ; MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom.
Publikováno v:
JAMA [JAMA] 2016 Oct 04; Vol. 316 (13), pp. 1383-1391.