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Autor:
Sulay Tovar, Mayte Alvarez-Crespo, Lucas C. González-Matías, Carlos Dieguez, Federico Mallo, Roberto Leiras, Diego Perez-Tilve
Publikováno v:
Diabetes. 56:143-151
Ghrelin is a potent orexigenic and adipogenic hormone that strongly influences fat deposition and the generation of hunger in obesity. Indeed, hyperghrelinemia appears to promote an increase in food intake as seen in Prader-Willi Syndrome (PWS). Exen
Publikováno v:
Diabetes. 55:819-825
To better understand the insulin-independent plasma glucose–lowering action of metformin, we used streptozotocin (STZ)-induced diabetic rats to investigate the possible mechanisms. Oral intake of metformin decreased the plasma glucose of STZ-induce