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Publikováno v:
Diabetes. 40:1150-1156
To determine the contribution of diuresis-induced bladder hypertrophy, which accompanies the diabetic state, on the biochemical and functional alterations observed in the diabetic bladder, we compared three experimental groups: 8-wk streptozocin (STZ
Autor:
Ole Gøtzsche
Publikováno v:
Diabetes. 32:1110-1116
The myocardial β-receptor adenylate cyclase system was investigated in short-term streptozotocin-diabetic rats. Earlier reports of a decreased sensitivity of the myocardium to isoproterenol (ISO) in these animals were elucidated by measuring the in
Publikováno v:
Diabetes. 32:881-886
To more fully characterize the alterations in myocardial adrenergic and cholinergic receptors induced by the diabetic state, we investigated the binding characteristics of (–) [3H] dihydroalprenolol to beta adrenergic receptors (bAR), [3H] prazosin
Autor:
Bruce D. Cherksey, Norman Altszuler
Publikováno v:
Diabetes. 33:499-503
Previous in vivo findings indicated that alpha-adrenergic blocking agents enhanced tolbutamide-induced insulin secretion, whereas beta-blockade attenuated it. In the present study, the interaction of tolbutamide and glyburide with the rat islet adren