Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Seppo Auriola"'
Autor:
Katja Häkkinen, Wilma Kiander, Heidi Kidron, Markku Lähteenvuo, Lea Urpa, Jonne Lintunen, Kati-Sisko Vellonen, Seppo Auriola, Minna Holm, Kaisla Lahdensuo, Olli Kampman, Erkki Isometsä, Tuula Kieseppä, Jouko Lönnqvist, Jaana Suvisaari, Jarmo Hietala, Jari Tiihonen, Aarno Palotie, Ari V. Ahola-Olli, Mikko Niemi
Publikováno v:
Molecular Pharmaceutics. 20:1500-1508
Variants in the SLCO1B1 (solute carrier organic anion transporter family member 1B1) gene encoding the OATP1B1 (organic anion transporting polypeptide 1B1) protein are associated with altered transporter function that can predispose patients to adver
Autor:
Seppo Auriola, Kasper B. Hansen, Mikko Gynther, Yevheniia Ishchenko, Darryl S. Pickering, Birgitte Nielsen, Aleksanteri Petsalo, Younes Larsen, Liwei Han, Jacob C. Hansen, Silke Kayser, Ilaria Proietti Silvestri, Tarja Malm, Lennart Bunch
Publikováno v:
Journal of Medicinal Chemistry. 60:9885-9904
The most common solid tumors show intrinsic multidrug resistance (MDR) or inevitably acquire suchwhen treated with anticancer drugs. In this work, we describe the discovery of a peripherally restricted, potent, competitive NMDA receptor antagonist 1l
Autor:
Arto Urtti, Shin Ichi Akanuma, Yasuo Uchida, Masanori Tachikawa, Zhengyu Zhang, Seppo Auriola, Ken Ichi Hosoya, Yoshiyuki Kubo, Satoshi Hirano, Daisuke Ando, Tetsuya Terasaki
Publikováno v:
Molecular Pharmaceutics. 14:3729-3738
The purpose of this study was to determine absolute protein expression levels of transporters at the porcine inner blood-retinal barrier (BRB) and to compare the transporter protein expression quantitatively among the inner BRB, outer BRB, blood-brai
Autor:
Seppo Auriola, Tuula H. Soininen, Ali Koskela, Reijo Karjalainen, Riitta Julkunen-Tiitto, Niina Saviranta, Mikko Anttonen
Publikováno v:
Journal of Agricultural and Food Chemistry. 58:12286-12291
Crowberry (Empetrum nigrum L.) is a relatively under-utilized wild berry that occurs widely throughout the northern hemisphere such as in Canada, Eurasia, and northern Europe. In this work, the anthocyanins of crowberries were analyzed from four geog
Autor:
Sirpa Kärenlampi, Seppo Auriola, Richard M. Röhlig, Mikko Anttonen, Karl-Heinz Engel, Satu Lehesranta
Publikováno v:
Journal of Proteome Research. 9:6160-6168
Comparative targeted compositional analysis is currently an important element in the safety assessment of genetically modified plants. Profiling methods have been suggested as nontargeted tools to improve the detection of possible unintended effects.
Autor:
Arto Urtti, Paavo Honkakoski, Alex Azhayev, Ilpo Jääskeläinen, Unni Tengvall, Seppo Rönkkö, Harri Lönnberg, Elena Azhayeva, Seppo Auriola, Maxim Antopolsky
Publikováno v:
Bioconjugate Chemistry. 10:598-606
Eighteen peptide-oligonucleotide phosphorothioate conjugates were prepared in good yield and thoroughly characterized with electrospray ionization mass spectra. When applied to the living cells, conjugates exhibiting membrane translocation and nuclea
Publikováno v:
Analytical Chemistry. 68:3907-3911
Capillary electrophoresis in poly(ethylene glycol) (PEG) solution-filled uncoated silica capillaries was demonstrated to be suitable for separation of oligonucleotides in 100 mM ammonium formate (pH 4.5) buffers. Reversed polarity (−30 kV at the in