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pro vyhledávání: '"Jan B. Koenderink"'
Autor:
Heike Dinter-Heidorn, Jan B. Koenderink, Jeroen J. M. W. van den Heuvel, Frans G. M. Russel, Hanneke G. M. Wittgen, Rick Greupink, Petra H.H. van den Broek
Publikováno v:
Molecular Pharmaceutics, 9, 5, pp. 1351-60
Molecular Pharmaceutics, 9, 1351-60
Molecular Pharmaceutics, 9, 1351-60
Contains fulltext : 107834.pdf (Publisher’s version ) (Closed access) Although the CB1 receptor antagonist/inverse agonist rimonabant has positive effects on weight loss and cardiometabolic risk factors, neuropsychiatric side effects have prompted
Publikováno v:
Biochemistry, 39, pp. 1330-1337
Biochemistry, 39, 1330-1337
Biochemistry, 39, 1330-1337
To study the role of Glu795offresent in the fifth transmembrane domain of the alpha-subunit of gastric H+,K+-ATPase, several mutants were generated and expressed in Sf9 insect cells. The E795Q mutant had rather similar properties as the wild-type enz