Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Qingzhen Yu"'
Autor:
Yiding Zhang, Zhen Chen, Ran Cheng, Tuo Shao, Yihan Shao, Qingzhen Yu, Jun-An Ma, Kuan Hu, Xiaoyun Deng, Akiko Hatori, Steven H. Liang, Lee Josephson, Hualong Fu, Kenneth Dahl, Neil Vasdev, Michael A. Schafroth, Masayuki Fujinaga, Lin Xie, Christopher J. Fowler, Shuyin Gu, Thomas Lee Collier, Lu Wang, Benjamin F. Cravatt, Jian Rong, Daisuke Ogasawara, Tomoteru Yamasaki, Bao Liang, Yuancheng Gou, Ming-Rong Zhang, Xiaofei Zhang, Katsushi Kumata, Genwei Zhang, Wakana Mori, Jingjin Chen
Publikováno v:
Journal of Medicinal Chemistry. 62:3336-3353
Monoacylglycerol lipase (MAGL) is a serine hydrolase that degrades 2-arachidonoylglycerol (2-AG) in the endocannabinoid system (eCB). Selective inhibition of MAGL has emerged as a potential therapeutic approach for the treatment of diverse pathologic
Autor:
Tuo Shao, Genwei Zhang, Stephen F. Traynelis, Lee Josephson, Wei Han, Steven H. Liang, Vasily Belov, Jian Rong, Xiaoyun Deng, Hongjie Yuan, Weiting Tang, Pilar Giffenig, Mikhail Papisov, James B. Daunais, April T. Davenport, Qingzhen Yu, Zhen Chen, Scott J. Myers, Yihan Shao, Xiaofei Zhang, Zijing Li, Hualong Fu, Lu Wang
Publikováno v:
ACS Chem Neurosci
GluN2B is the most studied subunit of N-methyl-D-aspartate receptors (NMDARs) and implicated in the pathologies of various central nervous system disorders and neurodegenerative diseases. As pan NMDAR antagonists often produce debilitating side effec