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Autor:
Daniel I. Benjamin, Alessandro Aliverti, Antonello Mai, Sergio Valente, Biagina Marrocco, Daniel K. Nomura, Andrea Mattevi, Simone Nenci, Valentina Piano
Publikováno v:
ACS Chemical Biology. 10:2589-2597
Dysregulated ether lipid metabolism is an important hallmark of cancer cells. Previous studies have reported that lowering ether lipid levels by genetic ablation of the ether lipid-generating enzyme alkyl-glycerone phosphate synthase (AGPS) lowers ke