Zobrazeno 1 - 1
of 1
pro vyhledávání: '"Katherine P. Yates"'
Hepatocyte TLR4 triggers inter-hepatocyte Jagged1/Notch signaling to determine NASH-induced fibrosis
Autor:
Michele Carrer, Li Qiang, Xiaobo Wang, Kyeong Jin Kim, Changyu Zhu, Utpal B. Pajvani, Katherine P. Yates, Luca Valenti, Junjie Yu, Thorsten Sadowski, Ira Tabas, Joel E. Lavine, Paola Dongiovanni, Alberto Bartolomé
Publikováno v:
Sci Transl Med
Aberrant hepatocyte Notch activity is critical to the development of nonalcoholic steatohepatitis (NASH)–induced liver fibrosis, but mechanisms underlying Notch reactivation in developed liver are unclear. Here, we identified that increased express