Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Yousef G."'
Autor:
Yousef G. Amaar, Mark E. Reeves
Publikováno v:
Cancer Research. 82:3839-3839
Introduction: Tumor microenvironment (TME) plays a vital role in tumor invasion and metastasis and provides a rich environment for identifying novel therapeutic targets. The TME landscape consists of extracellular matrix (ECM) and stromal cells. ECM
Autor:
Yousef G. Amaar, Mark E. Reeves
Publikováno v:
Cancer Research. 80:2525-2525
Introduction: In previous published work we have shown that RASSF1C promotes expression of PIWIL1 and PIWI interacting RNAs (piRNAs) in lung cancer cells, suggesting the hypothesis that that the RASSF1C-PIWI-piRNA pathway may promote lung cancer cell
Autor:
Mark E. Reeves, Yousef G. Amaar
Publikováno v:
Cancer Research. 78:365-365
Introduction: Epigenomic regulation is becoming critically important in human cancers as epigenetically regulated genes can be used as biomarkers for diagnosis, prognosis, molecular classification of tumors, and predicting response to therapies. Henc
Publikováno v:
Cancer Research. 75:2146-2146
Introduction: RASSF1C is emerging as an important oncoprotein in lung cancer cell growth. We have shown that RASSF1C promotes lung cancer cell proliferation and migration; and RASSF1C up-regulates important genes in lung cancer cell growth that inclu
Publikováno v:
Cancer Research. 74:2454-2454
Introduction: We have previously shown that RASSF1C promotes cell proliferation, migration and attenuates apoptosis in cancer cells. We have also shown that RASSF1C is significantly up-regulated in breast and lung cancer tissues compared to normal ti
Publikováno v:
Cancer Research. 73:4288-4288
Introduction: Recently, RASSF1A has been shown to mediate the apoptotic effects of TNF-α by interacting with the mammalian sterile 20-like kinase 1 and 2 (MST1/2) through the Salvador/Rassf/Hippo (SARAH) domain leading to MST1/2 phosphorylation acti
Publikováno v:
Cancer Research. 71:1139-1139
Breast cancer will kill more than 40,000 women in the United States this year, second in cancer deaths only to carcinoma of the lung. Therefore, a better understanding of the molecules and pathways that lead to breast cancer development is important