Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Reshma Jagsi"'
Autor:
Michael Dykstra, Jessica Thompson, Jessica Aldous, Shannon Jiang, Tasha Hughes, James Hayman, Aleksandar Dragovic, Jennifer Shah, Alfred Chang, Corey W. Speers, Michael Sabel, Lesly Dossett, Matthew Schipper, Reshma Jagsi
Publikováno v:
Cancer Research. 83:P1-09
Purpose/Objectives To assess whether an association exists between surgical localization technique and size of lumpectomy cavity on radiation (RT) planning CT scan. Adjuvant RT with boost to lumpectomy cavity has been shown to improve local control c
Autor:
Julia White, Reena S. Cecchini, Eleanor E. Harris, Eleftherios (Terry) Mamounas, Daniel Stover, Patricia A. Ganz, Reshma Jagsi, Carmen Bergom, Valérie Théberge, Mahmoud B. El-Tamer, Richard Zellars, Dean A. Shumway, Guang-Pei Chen, Stewart J. Anderson, Thomas B. Julian, Norman Wolmark, Wendy Rea
Publikováno v:
Cancer Research. 83:OT1-12
BACKGROUND: Approximately 50% of newly diagnosed breast cancers are stage 1, with the majority being ER/PR-positive, HER2-negative. Genomic assays such as Oncotype DX® have identified pts with reduced distant metastasis and without benefit from chem
Autor:
Corey Speers, Reshma Jagsi, Lori J. Pierce, Shyam Nyati, Meilan Liu, Cassandra L. Ritter, Nicole Hirsh, Amanda Zhang, Dafydd G. Thomas, Eric Olsen, Meleah Cameron, Kari Wilder-Romans, Benjamin C. Chandler, Leah Moubadder, Andrea M. Pesch, Anna R. Michmerhuizen
Higher doses of olaparib are sufficient to inhibit PAR formation in BRCA1-mutant SUM-149 cells. At higher concentrations of olaparib (1μM), combination treatment of PARP1 inhibition and radiation decreases PAR in a comparable manner to lower doses o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::623d55d5dd22fc6feaa49169a3f1f0b6
https://doi.org/10.1158/1535-7163.22518895
https://doi.org/10.1158/1535-7163.22518895
Autor:
Corey Speers, Reshma Jagsi, Lori J. Pierce, Shyam Nyati, Meilan Liu, Cassandra L. Ritter, Nicole Hirsh, Amanda Zhang, Dafydd G. Thomas, Eric Olsen, Meleah Cameron, Kari Wilder-Romans, Benjamin C. Chandler, Leah Moubadder, Andrea M. Pesch, Anna R. Michmerhuizen
Ki67 and p16 levels are decreased in tumors from animals treated with radiation and combination PARP-inhibitor and radiation. SUM-190 xenograft tumors that were harvested from mice at the completion of the long-term in vivo study. Protein expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::057703d4bde74df38c00e6668f4ad8bf
https://doi.org/10.1158/1535-7163.22518892
https://doi.org/10.1158/1535-7163.22518892
Autor:
Corey Speers, Reshma Jagsi, Lori J. Pierce, Shyam Nyati, Meilan Liu, Cassandra L. Ritter, Nicole Hirsh, Amanda Zhang, Dafydd G. Thomas, Eric Olsen, Meleah Cameron, Kari Wilder-Romans, Benjamin C. Chandler, Leah Moubadder, Andrea M. Pesch, Anna R. Michmerhuizen
Total PARP1 levels do not change with treatment but PAR levels are decreased by PARPi. Total levels of PARP1 were assessed in tumors from mice treated with olaparib. Olaparib treatment did not affect PARP1 protein expression by IHC in olaparib-alone,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::824f34ca3b79b528a88bfc2ddafacc24
https://doi.org/10.1158/1535-7163.22518886
https://doi.org/10.1158/1535-7163.22518886
Autor:
Corey Speers, Reshma Jagsi, Lori J. Pierce, Shyam Nyati, Meilan Liu, Cassandra L. Ritter, Nicole Hirsh, Amanda Zhang, Dafydd G. Thomas, Eric Olsen, Meleah Cameron, Kari Wilder-Romans, Benjamin C. Chandler, Leah Moubadder, Andrea M. Pesch, Anna R. Michmerhuizen
Enhancement ratios and toxicity for IBC clonogenic survival assays. Average radiation enhancement ratio (rER) and toxicity values are shown for each treatment in SUM-190 (A), MDA-IBC-3 (B), and SUM-149 (C) cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84c8c1b479d5f50abc8f6cb482defd87
https://doi.org/10.1158/1535-7163.22518898.v1
https://doi.org/10.1158/1535-7163.22518898.v1
Autor:
Corey Speers, Reshma Jagsi, Lori J. Pierce, Shyam Nyati, Meilan Liu, Cassandra L. Ritter, Nicole Hirsh, Amanda Zhang, Dafydd G. Thomas, Eric Olsen, Meleah Cameron, Kari Wilder-Romans, Benjamin C. Chandler, Leah Moubadder, Andrea M. Pesch, Anna R. Michmerhuizen
Extended methods for immunohistochemistry. Antibodies used in immunohistochemistry experiments are listed with each of the corresponding dilutions, retrieval techniques, and positive controls.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dec1ab52d25aad68186ffb5ea9a1a23
https://doi.org/10.1158/1535-7163.22518883
https://doi.org/10.1158/1535-7163.22518883
Autor:
Corey Speers, Reshma Jagsi, Lori J. Pierce, Shyam Nyati, Meilan Liu, Cassandra L. Ritter, Nicole Hirsh, Amanda Zhang, Dafydd G. Thomas, Eric Olsen, Meleah Cameron, Kari Wilder-Romans, Benjamin C. Chandler, Leah Moubadder, Andrea M. Pesch, Anna R. Michmerhuizen
Sustained locoregional control of disease is a significant issue in patients with inflammatory breast cancer (IBC), with local control rates of 80% or less at 5 years. Given the unsatisfactory outcomes for these patients, there is a clear need for in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08ab813eb94ed0666f01ed7b66b76c82
https://doi.org/10.1158/1535-7163.c.6542167
https://doi.org/10.1158/1535-7163.c.6542167
Autor:
Julia White, Stewart J Anderson, Eleanor ER Harris, Eleftherios P Mamounas, Daniel G Stover, Patricia A Ganz, Reshma Jagsi, Reena S Cecchini, Carmen Bergom, Valerie Theberge, Mahmoud El-Tamer, Rich C Zellars, Dean A Shumway, Guang-Pei Chen, Thomas B Julian, Norman Wolmark
Publikováno v:
Cancer Research. 82:P3-18
Roughly 50% of newly diagnosed breast cancer is stage 1, the majority being ER/PR positive, HER2- negative. Genomic assays such as Oncotype DX® have identified patients with reduced distant metastasis and lack of chemotherapy benefit, allowing patie
Autor:
Derek Bergsma, James A. Hayman, Maggie Grubb, Michael M. Dominello, T.P. Boike, Reshma Jagsi, Lori J. Pierce, Kent A. Griffith, Joshua T. Dilworth, Frank A. Vicini, Amit Bhatt, Jean M. Moran
Publikováno v:
Cancer Research. 81:PD4-07
BACKGROUND: Current national guidelines encourage consideration for treating the at-risk regional nodes (axillary, supraclavicular, and/or internal mammary) with directed regional nodal irradiation (RNI) during post-lumpectomy radiotherapy for high r