Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Rene Gonzalez"'
Autor:
Richard P. Tobin, Dasha T. Cogswell, Victoria M. Cates, Dana M. Davis, Jessica S.W. Borgers, Robert J. Van Gulick, Elizabeth Katsnelson, Kasey L. Couts, Kimberly R. Jordan, Dexiang Gao, Eduardo Davila, Theresa M. Medina, Karl D. Lewis, Rene Gonzalez, Ross W. McFarland, William A. Robinson, Martin D. McCarter
Publikováno v:
Clinical Cancer Research. 29:1209-1219
Purpose: A phase Ib/II clinical trial was conducted to evaluate the safety and efficacy of the combination of all-trans retinoic acid (ATRA) with pembrolizumab in patients with stage IV melanoma. Patients and Methods: Anti–PD-1 naïve patients with
Autor:
William A. Robinson, Robert C. Doebele, Theresa Medina, Rene Gonzalez, Aik-Choon Tan, Matthew J. Rioth, Yiqun G. Shellman, John J. Tentler, Edna Chow-Maneval, Pratik Multani, Carol Amato, Allison Applegate, Keith Wells, Todd M. Pitts, Anh Le, Jennifer D. Hintzsche, Jason Christiansen, Danielle Murphy, Stacey M. Bagby, Jacqueline A. Turner, Judson Bemis, Kasey L. Couts
Non-specific immunoblot bands in MB 1692 and MB 1374
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4686ba4268cdf469c3029bca5d3d3e32
https://doi.org/10.1158/1535-7163.22509220
https://doi.org/10.1158/1535-7163.22509220
Autor:
William A. Robinson, Robert C. Doebele, Theresa Medina, Rene Gonzalez, Aik-Choon Tan, Matthew J. Rioth, Yiqun G. Shellman, John J. Tentler, Edna Chow-Maneval, Pratik Multani, Carol Amato, Allison Applegate, Keith Wells, Todd M. Pitts, Anh Le, Jennifer D. Hintzsche, Jason Christiansen, Danielle Murphy, Stacey M. Bagby, Jacqueline A. Turner, Judson Bemis, Kasey L. Couts
Overexpression of EML4-ALK, ALKATI, and wtALK in NIH3T3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46cce89e45ae899422ce8ae48706f117
https://doi.org/10.1158/1535-7163.22509217.v1
https://doi.org/10.1158/1535-7163.22509217.v1
Data from ALK Inhibitor Response in Melanomas Expressing EML4-ALK Fusions and Alternate ALK Isoforms
Autor:
William A. Robinson, Robert C. Doebele, Theresa Medina, Rene Gonzalez, Aik-Choon Tan, Matthew J. Rioth, Yiqun G. Shellman, John J. Tentler, Edna Chow-Maneval, Pratik Multani, Carol Amato, Allison Applegate, Keith Wells, Todd M. Pitts, Anh Le, Jennifer D. Hintzsche, Jason Christiansen, Danielle Murphy, Stacey M. Bagby, Jacqueline A. Turner, Judson Bemis, Kasey L. Couts
Oncogenic ALK fusions occur in several types of cancer and can be effectively treated with ALK inhibitors; however, ALK fusions and treatment response have not been characterized in malignant melanomas. Recently, a novel isoform of ALK (ALKATI) was r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96e0f98b7a7fa2b66364bbf082f02cac
https://doi.org/10.1158/1535-7163.c.6539227.v1
https://doi.org/10.1158/1535-7163.c.6539227.v1
Autor:
Martin D. McCarter, William A. Robinson, Ross W. McFarland, Rene Gonzalez, Karl D. Lewis, Theresa M. Medina, Eduardo Davila, Dexiang Gao, Kimberly R. Jordan, Kasey L. Couts, Elizabeth Katsnelson, Robert J. Van Gulick, Jessica S.W. Borgers, Dana M. Davis, Victoria M. Cates, Dasha T. Cogswell, Richard P. Tobin
Purpose:A phase Ib/II clinical trial was conducted to evaluate the safety and efficacy of the combination of all-trans retinoic acid (ATRA) with pembrolizumab in patients with stage IV melanoma.Patients and Methods:Anti–PD-1 naïve patients with st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24b6c67c89fc45f804c3ed30132aaba1
https://doi.org/10.1158/1078-0432.c.6532811
https://doi.org/10.1158/1078-0432.c.6532811
Autor:
William A. Robinson, Robert C. Doebele, Theresa Medina, Rene Gonzalez, Aik-Choon Tan, Matthew J. Rioth, Yiqun G. Shellman, John J. Tentler, Edna Chow-Maneval, Pratik Multani, Carol Amato, Allison Applegate, Keith Wells, Todd M. Pitts, Anh Le, Jennifer D. Hintzsche, Jason Christiansen, Danielle Murphy, Stacey M. Bagby, Jacqueline A. Turner, Judson Bemis, Kasey L. Couts
Primer sequences
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06f88f7ccbff1645b88519124ac1232b
https://doi.org/10.1158/1535-7163.22509205.v1
https://doi.org/10.1158/1535-7163.22509205.v1
Autor:
Martin D. McCarter, William A. Robinson, Ross W. McFarland, Rene Gonzalez, Karl D. Lewis, Theresa M. Medina, Eduardo Davila, Dexiang Gao, Kimberly R. Jordan, Kasey L. Couts, Elizabeth Katsnelson, Robert J. Van Gulick, Jessica S.W. Borgers, Dana M. Davis, Victoria M. Cates, Dasha T. Cogswell, Richard P. Tobin
Characteristics of patients experiencing clinical benefit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::616d4ce76fe5b82e2a0eb0067a364b89
https://doi.org/10.1158/1078-0432.22494979.v1
https://doi.org/10.1158/1078-0432.22494979.v1
Autor:
Martin D. McCarter, William A. Robinson, Ross W. McFarland, Rene Gonzalez, Karl D. Lewis, Theresa M. Medina, Eduardo Davila, Dexiang Gao, Kimberly R. Jordan, Kasey L. Couts, Elizabeth Katsnelson, Robert J. Van Gulick, Jessica S.W. Borgers, Dana M. Davis, Victoria M. Cates, Dasha T. Cogswell, Richard P. Tobin
Supplementary figure 1. (A) Changes in other circulating cytokines. Colored box denotes the time when the patients were being treated with ATRA. (B) example gating strategy for CD8+ T cell activation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::311bb7e612c0c81d35b63683aa70fc69
https://doi.org/10.1158/1078-0432.22494997
https://doi.org/10.1158/1078-0432.22494997
Autor:
Antonio Jimeno, Rene Gonzalez, Dennis R. Roop, William Robinson, Jing H. Wang, Xiao-Jing Wang, Theresa Medina, Hilary Somerset, Aik-Choon Tan, Dexiang Gao, Randi Yeager, Bettina Miller, Karina Gomez, Cera Nieto, Phuong N. Le, Loni Perrenoud, Julie Reisinger, Tugs-Saikhan Chimed, Stephen B. Keysar, Nathaniel Alzofon, J. Jason Morton
Resistance to immunotherapy is a significant challenge, and the scarcity of human models hinders the identification of the underlying mechanisms. To address this limitation, we constructed an autologous humanized mouse (aHM) model with hematopoietic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::655a6f1c1b66b2ca94647218902d75a6
https://doi.org/10.1158/1541-7786.c.6545108.v1
https://doi.org/10.1158/1541-7786.c.6545108.v1
Autor:
Antonio Jimeno, Rene Gonzalez, Dennis R. Roop, William Robinson, Jing H. Wang, Xiao-Jing Wang, Theresa Medina, Hilary Somerset, Aik-Choon Tan, Dexiang Gao, Randi Yeager, Bettina Miller, Karina Gomez, Cera Nieto, Phuong N. Le, Loni Perrenoud, Julie Reisinger, Tugs-Saikhan Chimed, Stephen B. Keysar, Nathaniel Alzofon, J. Jason Morton
Table S1. Expanded HSPC engraftment into mouse cohorts Table S2. Human immune cell presence in HM tissues Table S3a. CUHM003 mutations present at diagnosis b. Additional CUHM003 mutations present at progression c. CUHM005 mutations present at diagnos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34c3fbcf5bdeea96081d6cb3e0e4b08c
https://doi.org/10.1158/1541-7786.22526474.v1
https://doi.org/10.1158/1541-7786.22526474.v1