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pro vyhledávání: '"Pablo C, Okhuysen"'
Autor:
Alan Wang, Asha S. Multani, Guocan Wang, Sarah blutt, Mao Xizeng, Wenting Liao, Jianhua Zhang, Di Zhao, Denise J. Spring, Ronald A. DePinho, Deepavali Chakravarti, Prasenjit Dey, Kyle Chang, Pablo C. Okhuysen, Mary K. Estes, Christoper Terranova, Baoli Hu, Eduardo Vilar, Pingping Hou
Publikováno v:
Cancer Research. 79:LB-290
The molecular instigators and therapeutic strategies for inflammatory bowel disease (IBD) are limited. Here, telomere dysfunction is shown to activate pAtm/c-Abl-mediated phosphorylation and stabilization of Yap1 up-regulates pro-IL-18 expression, a