Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Masahiro Hirakawa"'
Autor:
Hajime Nakamura, Kohichi Takada, Yuki Ikeda, Makoto Yoshida, Masahiro Hirakawa, Yusuke Kamihara, Koji Miyanishi, Yusuke Sugama, Yohei Arihara, Makoto Usami, Masayoshi Kobune, Naotaka Hayasaka, Junji Kato, Shohei Kikuchi
Publikováno v:
Cancer Research. 77:2112-2112
Pancreatic cancer is highly chemo-resistant associated with oncogenic mutations such as KRAS and/or p53. The effect of conventional chemotherapy is not sufficient and new target and strategy is urgently needed. The forkhead box (Fox) proteins are mul
Autor:
Yasushi Sato, Masahiro Hirakawa, Makoto Yoshida, Fumito Tamura, Rishu Takimoto, Michihiro Ono, Junji Kato, Takahiro Osuga
Publikováno v:
Cancer Research. 74:1123-1123
Background: Transforming growth factor-ß (TGF-ß) is a major inducer of epithelial-mesenchymal transition (EMT) in different cell types. TGF-ß-mediated EMT is thought to contribute to tumor cell spread and metastasis. Sialyl Lewis antigens synthesi
Autor:
Fumito Tamura, Masahiro Hirakawa, Yasushi Sato, Michihiro Ono, Rishu Takimoto, Junji Kato, Takahiro Osuga, Makoto Yoshida
Publikováno v:
Cancer Research. 74:4463-4463
Background & Aims: Prognosis of patients with metastatic colorectal cancer (CRC) has been improving by introduction of molecular targeting therapy combined with chemotherapeutic agents. However, metastatic CRC still needs new strategies to improve tr
Autor:
Masahiro Hirakawa, Kazuyuki Murase, Koji Miyanishi, Masayoshi Kobune, Yoshiyuki Onuma, Makoto Yoshida, Rishu Takimoto, Yasushi Sato, Tsutomu Sato, Junji Kato
Publikováno v:
Cancer Research. 70:3936-3936
Accumulating evidence suggests that DNA repair enzyme activity may predict sensitivity to chemotherapeutic agents in cancer cells. The status of a DNA repair enzyme, such as XPF/ERCC4 or XPD/ERCC2, has been reported to serve as a prognostic indicator