Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Liana Adam"'
Autor:
Colin Dinney, Menashe Bar-Eli, David McConkey, Arlene Siefker-Radtke, Hua Wang, George Calin, Ameeta Arora, Milena Nicoloso, Wei Qi, Woonyoung Choi, Meng Zhong, Liana Adam
Purpose: The epithelial-to-mesenchymal transition (EMT) is a cell development-regulated process in which noncoding RNAs act as crucial modulators. Recent studies have implied that EMT may contribute to resistance to epidermal growth factor receptor (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab3d8c9e63d5544adae6b58e2b7d997a
https://doi.org/10.1158/1078-0432.c.6517474
https://doi.org/10.1158/1078-0432.c.6517474
Autor:
Michael J. Overman, Paul Scheet, Scott Kopetz, Chad Huff, Stefan T. Arold, Ganiraju Manyam, Joe Ensor, Michael T. Tetzlaff, David Menter, Huamin Wang, Yulun Liu, Wenhui Wu, Yao Yu, Richard Fowler, F. Anthony San Lucas, Liana Adam
Purpose:Little is known about the genetic alterations characteristic of small bowel adenocarcinoma (SBA). Our purpose was to identify targetable alterations and develop experimental models of this disease.Experimental Design: Whole-exome sequencing (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88d5881fedd9be635ffbe52a90db38d0
https://doi.org/10.1158/1078-0432.c.6529001
https://doi.org/10.1158/1078-0432.c.6529001
Autor:
Colin Dinney, Menashe Bar-Eli, David McConkey, Arlene Siefker-Radtke, Hua Wang, George Calin, Ameeta Arora, Milena Nicoloso, Wei Qi, Woonyoung Choi, Meng Zhong, Liana Adam
Conflict of Interest Form 1 from miR-200 Expression Regulates Epithelial-to-Mesenchymal Transition in Bladder Cancer Cells and Reverses Resistance to Epidermal Growth Factor Receptor Therapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42c55b3ae9e331773dec9c92877b6585
https://doi.org/10.1158/1078-0432.22440103
https://doi.org/10.1158/1078-0432.22440103
Autor:
Liana Adam, Menashe Bar-Eli, Alan J. Diehl, David J. McConkey, Gordon Brown, Colin P.N. Dinney, Wassim Kassouf
Activation of the epidermal growth factor receptor (EGFR) and downstream signaling pathways, such as phosphatidylinositol-3 kinase/Akt and Ras/mitogen-activated protein kinase (MAPK), have been implicated in causing resistance to EGFR-targeted therap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a53e8a4c586490409e225f0d55a22f03
https://doi.org/10.1158/0008-5472.c.6494133
https://doi.org/10.1158/0008-5472.c.6494133
Autor:
Liana Adam, Menashe Bar-Eli, Alan J. Diehl, David J. McConkey, Gordon Brown, Colin P.N. Dinney, Wassim Kassouf
Supplementary Figure 1 from Uncoupling between Epidermal Growth Factor Receptor and Downstream Signals Defines Resistance to the Antiproliferative Effect of Gefitinib in Bladder Cancer Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25d4a96646c3c27057102060c4dc0090
https://doi.org/10.1158/0008-5472.22364322
https://doi.org/10.1158/0008-5472.22364322
Autor:
Stefan T. Arold, Huamin Wang, Ganiraju C. Manyam, Chad D. Huff, Richard G. Fowler, Scott Kopetz, Paul Scheet, Yao Yu, Yulun Liu, Joe Ensor, David G. Menter, Michael T. Tetzlaff, F. Anthony San Lucas, Liana Adam, Wenhui Wu, Michael J. Overman
Publikováno v:
Clinical Cancer Research. 25:641-651
Purpose: Little is known about the genetic alterations characteristic of small bowel adenocarcinoma (SBA). Our purpose was to identify targetable alterations and develop experimental models of this disease. Experimental Design: Whole-exome sequencing
Autor:
Milena S. Nicoloso, George A. Calin, Meng Zhong, Ameeta Arora, Arlene O. Siefker-Radtke, Wei Qi, Menashe Bar-Eli, Hua Wang, Liana Adam, David J. McConkey, Woonyoung Choi, Colin P.N. Dinney
Publikováno v:
Clinical Cancer Research. 15:5060-5072
Purpose: The epithelial-to-mesenchymal transition (EMT) is a cell development-regulated process in which noncoding RNAs act as crucial modulators. Recent studies have implied that EMT may contribute to resistance to epidermal growth factor receptor (
Publikováno v:
Clinical Cancer Research. 14:6161-6170
Purpose: Abnormalities in the expression and signaling pathways downstream of epidermal growth factor receptor (EGFR) contribute to progression, invasion, and maintenance of the malignant phenotype in human cancers. Accordingly, biological agents, su
Autor:
Mark F. Munsell, Ameeta Arora, Marissa Shrader, David J. McConkey, Liana Adam, Teruo Inamoto, Colin P.N. Dinney, Xifeng Wu, Arlene O. Siefker-Radtke, Gordon A. Brown, Dan Theodorescu, Peter C. Black, Menashe Bar-Eli
Publikováno v:
Clinical Cancer Research. 14:1478-1486
Purpose: Epidermal growth factor receptor (EGFR) is an attractive target for the treatment of urothelial carcinoma, but a clinical response can be expected in only a small proportion of patients. The aim of this study was to define molecular markers
Autor:
Menashe Bar-Eli, Colin P.N. Dinney, David J. McConkey, Maria Simona Pino, Laura M. Lashinger, Liana Adam, Marissa Shrader
Publikováno v:
Cancer Research. 67:1430-1435
In a previous study, we found that the small-molecule epidermal growth factor receptor (EGFR) inhibitor gefitinib (ZD1839, Iressa) blocked cell proliferation at biologically relevant concentrations in approximately one third (6 of 17) of human bladde