Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Leandro Cerchietti"'
Autor:
Ari M. Melnick, Hening Lin, Shawn M. Davidson, Leandro Cerchietti, Zhengming Chen, Ling Wang, Hao Shen, Cihangir Duy, Noel R. Park, Jun Young Hong, Matthew R. Teater, Meng Li
Supplementary Data from Translational Activation of ATF4 through Mitochondrial Anaplerotic Metabolic Pathways Is Required for DLBCL Growth and Survival
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2719da4a1c15a7e05960ccb43f4fd2d1
https://doi.org/10.1158/2643-3230.22544175.v1
https://doi.org/10.1158/2643-3230.22544175.v1
Autor:
Ari M. Melnick, Hao Wu, Lorena Fontan, Ulrike Philippar, Tianbao Lu, Leandro Cerchietti, Nahuel Zamponi, Kojo S.J. Elenitoba-Johnson, Ozlem Onder, Ryan D. Morin, David W. Scott, Graham W. Slack, Andrew Lytle, Cem Meydan, Xiang Wang, Johana Gutierrez, Matt Teater, Liron David, Min Xia
Activated B cell–like diffuse large B-cell lymphomas (ABC-DLBCL) have unfavorable outcomes and chronic activation of CARD11–BCL10–MALT1 (CBM) signal amplification complexes that form due to polymerization of BCL10 subunits, which is affected by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25fe49233ab98dab165cd9c7b104aff3
https://doi.org/10.1158/2159-8290.c.6549644.v1
https://doi.org/10.1158/2159-8290.c.6549644.v1
Autor:
Ari M. Melnick, Hao Wu, Lorena Fontan, Ulrike Philippar, Tianbao Lu, Leandro Cerchietti, Nahuel Zamponi, Kojo S.J. Elenitoba-Johnson, Ozlem Onder, Ryan D. Morin, David W. Scott, Graham W. Slack, Andrew Lytle, Cem Meydan, Xiang Wang, Johana Gutierrez, Matt Teater, Liron David, Min Xia
Supplementary Figure from BCL10 Mutations Define Distinct Dependencies Guiding Precision Therapy for DLBCL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::144279868171f02eb7d99f3b0f9520d8
https://doi.org/10.1158/2159-8290.22541444.v1
https://doi.org/10.1158/2159-8290.22541444.v1
Autor:
Ari M. Melnick, Hao Wu, Lorena Fontan, Ulrike Philippar, Tianbao Lu, Leandro Cerchietti, Nahuel Zamponi, Kojo S.J. Elenitoba-Johnson, Ozlem Onder, Ryan D. Morin, David W. Scott, Graham W. Slack, Andrew Lytle, Cem Meydan, Xiang Wang, Johana Gutierrez, Matt Teater, Liron David, Min Xia
Supplementary Data from BCL10 Mutations Define Distinct Dependencies Guiding Precision Therapy for DLBCL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1993fe94eaca811e6dd0d6edec38a1b7
https://doi.org/10.1158/2159-8290.22541450
https://doi.org/10.1158/2159-8290.22541450
Autor:
Ari M. Melnick, Hening Lin, Shawn M. Davidson, Leandro Cerchietti, Zhengming Chen, Ling Wang, Hao Shen, Cihangir Duy, Noel R. Park, Jun Young Hong, Matthew R. Teater, Meng Li
Diffuse large B-cell lymphomas (DLBCL) are broadly dependent on anaplerotic metabolism regulated by mitochondrial SIRT3. Herein we find that translational upregulation of ATF4 is coupled with anaplerotic metabolism in DLBCLs due to nutrient deprivati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b29aa2580e0c53df6ab7ca251e9a6a2
https://doi.org/10.1158/2643-3230.c.6550560.v1
https://doi.org/10.1158/2643-3230.c.6550560.v1
Autor:
Leandro Cerchietti, Ari Melnick, John P. Leonard, Giorgio Inghirami, Katherine L. Borden, Randy D. Gascoyne, Lucy A. Godley, Fabrizio Tabbo, Amy Chadburn, Rita Shaknovich, Micheal Leser, Sarah Wyman, David W. Scott, Biljana Culjkovic, Aparna Vasanthakumar, Samprit Banerjee, Matthias Kormaksson, Peter Martin, Wayne Tam, Rebecca L. Elstrom, ShaoNing Yang, Thomas Clozel
Figure S5 - PDF file 224K, Toxicity studies in mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12229b5cf6bc86e4efd6d0e0b8d98300
https://doi.org/10.1158/2159-8290.22530860
https://doi.org/10.1158/2159-8290.22530860
Autor:
Ari Melnick, Iannis Aifantis, Weimin Ci, Olivier Elemento, Ivan Maillard, Patrick A. Zweidler-McKay, John P. Leonard, Kamala Bhatt, Wayne Tam, Zhuoning Li, Eric Perkey, Xabier Agirre, Katerina Hatzi, Yanwen Jiang, Camille W. Graham, Erin Oswald, Shao Ning Yang, Philmo Oh, Leandro Cerchietti, Martín Rivas, Mariano Cardenas, Ling Wang, Huimin Geng, Camille Lobry, Ester Valls
Supplementary Table S8. DLBCL p-values and rho values on GCB-DLBCL probesets for Notch2 pathway genes. (See Supplementary Figure S1G).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42efdd16395832aa1cd1f8e5ff4b8110
https://doi.org/10.1158/2159-8290.22532026.v1
https://doi.org/10.1158/2159-8290.22532026.v1
Autor:
Ari Melnick, Iannis Aifantis, Weimin Ci, Olivier Elemento, Ivan Maillard, Patrick A. Zweidler-McKay, John P. Leonard, Kamala Bhatt, Wayne Tam, Zhuoning Li, Eric Perkey, Xabier Agirre, Katerina Hatzi, Yanwen Jiang, Camille W. Graham, Erin Oswald, Shao Ning Yang, Philmo Oh, Leandro Cerchietti, Martín Rivas, Mariano Cardenas, Ling Wang, Huimin Geng, Camille Lobry, Ester Valls
Supplementary Figure S1. BCL6 displays a specific genomic localization pattern in FL. Supplementary Figure S2. Inverse correlation between BCL6 and NOTCH2 complex genes in primary GC B-cells. Supplementary Figure S3. GC reaction is impaired in Notch2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96a421adc5484b4841a2793ce3d9f32c
https://doi.org/10.1158/2159-8290.22532050
https://doi.org/10.1158/2159-8290.22532050
Autor:
Ari Melnick, Iannis Aifantis, Weimin Ci, Olivier Elemento, Ivan Maillard, Patrick A. Zweidler-McKay, John P. Leonard, Kamala Bhatt, Wayne Tam, Zhuoning Li, Eric Perkey, Xabier Agirre, Katerina Hatzi, Yanwen Jiang, Camille W. Graham, Erin Oswald, Shao Ning Yang, Philmo Oh, Leandro Cerchietti, Martín Rivas, Mariano Cardenas, Ling Wang, Huimin Geng, Camille Lobry, Ester Valls
Supplementary Table S3. Excel file containing the statistical analysis of the 184 FL targets with significant inverse correlation with BCL6.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dbcb295808f71307d5a658aa47ec088
https://doi.org/10.1158/2159-8290.22532038
https://doi.org/10.1158/2159-8290.22532038
Autor:
Leandro Cerchietti, Ari Melnick, John P. Leonard, Giorgio Inghirami, Katherine L. Borden, Randy D. Gascoyne, Lucy A. Godley, Fabrizio Tabbo, Amy Chadburn, Rita Shaknovich, Micheal Leser, Sarah Wyman, David W. Scott, Biljana Culjkovic, Aparna Vasanthakumar, Samprit Banerjee, Matthias Kormaksson, Peter Martin, Wayne Tam, Rebecca L. Elstrom, ShaoNing Yang, Thomas Clozel
Figure S6 - PDF file 110K, Daunorubicin uptake in DLBCL cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5baba6e126f93e7f319c84f088a1fd02
https://doi.org/10.1158/2159-8290.22530857
https://doi.org/10.1158/2159-8290.22530857