Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Hongbo Hu"'
Autor:
Cheng Jiang, Junxuan Lu, Hongbo Hu, Min Ye, Sangyub Kim, Wei Wu, Kartick Pramanik, Peixin Jiang, Su-Ni Tang, Shutao Yin, Michael W. Melkus, Yinhui Dong, Yong Zhang
Bufalin is a major cardiotonic compound in the traditional Chinese medicine, Chansu, prepared from toad skin secretions. Cell culture studies have suggested an anticancer potential involving multiple cellular processes, including differentiation, apo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac7e90f24d82a32e0daa1517395425d1
https://doi.org/10.1158/1535-7163.c.6537846.v1
https://doi.org/10.1158/1535-7163.c.6537846.v1
Autor:
Junxuan Lü, Margot P. Cleary, Joshua D. Liao, Yong Zhang, Hongbo Hu, Hyo-Jeong Lee, Guang-xun Li, Melissa J.L. Bonorden, Lei Wang
Supplementary Figure 1 from Methyl-Selenium Compounds Inhibit Prostate Carcinogenesis in the Transgenic Adenocarcinoma of Mouse Prostate Model with Survival Benefit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04f0267cbd3624840edbf1f8fd0787a6
https://doi.org/10.1158/1940-6207.22523298
https://doi.org/10.1158/1940-6207.22523298
Autor:
Cheng Jiang, Junxuan Lu, Hongbo Hu, Min Ye, Sangyub Kim, Wei Wu, Kartick Pramanik, Peixin Jiang, Su-Ni Tang, Shutao Yin, Michael W. Melkus, Yinhui Dong, Yong Zhang
Table S3 shows effect of bufalin on cyclins (CCN) and mini-chromosome maintenance (MCM) genes in LNCaP cells exposed for 24 h. Expressed relative to control set as unity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b577c4a9f7ffc36292205d8758d5102
https://doi.org/10.1158/1535-7163.22504770
https://doi.org/10.1158/1535-7163.22504770
Autor:
Cheng Jiang, Junxuan Lu, Hongbo Hu, Min Ye, Sangyub Kim, Wei Wu, Kartick Pramanik, Peixin Jiang, Su-Ni Tang, Shutao Yin, Michael W. Melkus, Yinhui Dong, Yong Zhang
Figure S1 shows A. Concentration-dependent reduction of number of adherent LNCaP cells exposed to increasing concentrations of bufalin for 96 h; B. Representative photomicrograph of LNCaP cells exposed to bufalin at 2 concentrations for 48 h. Figure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4eee35c0fa17d5f3ad7d297a6931708f
https://doi.org/10.1158/1535-7163.22504779
https://doi.org/10.1158/1535-7163.22504779
Autor:
Cheng Jiang, Junxuan Lu, Hongbo Hu, Min Ye, Sangyub Kim, Wei Wu, Kartick Pramanik, Peixin Jiang, Su-Ni Tang, Shutao Yin, Michael W. Melkus, Yinhui Dong, Yong Zhang
Table S2 shows down-regulated genes by 10 nM bufalin over vehicle control by over 40% or more in LNCaP cells exposed for 24 h. Expressed as fold over vehicle control set as unity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2d8862948aaf0f32f0db2e2081016d3
https://doi.org/10.1158/1535-7163.22504773.v1
https://doi.org/10.1158/1535-7163.22504773.v1
Autor:
Cheng Jiang, Junxuan Lu, Hongbo Hu, Min Ye, Sangyub Kim, Wei Wu, Kartick Pramanik, Peixin Jiang, Su-Ni Tang, Shutao Yin, Michael W. Melkus, Yinhui Dong, Yong Zhang
Table S1 shows upregulated genes by 10 nM bufalin over vehicle control by over 50% or more in LNCaP cells exposed for 24 h. Expressed as fold over vehicle control set as unity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14a88c2bed1bf2eb473eeb00d3e7fd43
https://doi.org/10.1158/1535-7163.22504776.v1
https://doi.org/10.1158/1535-7163.22504776.v1
Autor:
Xin Chen, Matthias Evert, Diego F. Calvisi, Hongbo Hu, Frank Dombrowski, Rosa M. Pascale, Alberto Porcu, Antonio Cossu, Shanshan Zhang, Li Che, John D. Gordan, Marina Serra, Maria G. Pilo, Silvia Ribback, Kirsten Utpatel, Antonio Cigliano, Yu Qiao, Jingxiao Wang, Haichuan Wang, Xianqiong Liu, Xinhua Song
Supplementary Figure 1. Activation of the CDK4/6 axis in human intrahepatic cholangiocarcinoma (ICC) specimens. Supplementary Figure 2. Levels of Rb1, CDK4, CDK6, E2F1, and Cyclin E1 mRNA in human intrahepatic cholangiocarcinoma (ICC) from The Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1aaf8d04086e71494691c82aae6922c1
https://doi.org/10.1158/1078-0432.22475808
https://doi.org/10.1158/1078-0432.22475808
Autor:
Xin Chen, Matthias Evert, Diego F. Calvisi, Hongbo Hu, Frank Dombrowski, Rosa M. Pascale, Alberto Porcu, Antonio Cossu, Shanshan Zhang, Li Che, John D. Gordan, Marina Serra, Maria G. Pilo, Silvia Ribback, Kirsten Utpatel, Antonio Cigliano, Yu Qiao, Jingxiao Wang, Haichuan Wang, Xianqiong Liu, Xinhua Song
Purpose:Intrahepatic cholangiocarcinoma (ICC) is an aggressive cancer type, lacking effective therapies and associated with a dismal prognosis. Palbociclib is a selective CDK4/6 inhibitor, which has been shown to suppress cell proliferation in many e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3286c9f21893764ea58476273e6d23a
https://doi.org/10.1158/1078-0432.c.6529182
https://doi.org/10.1158/1078-0432.c.6529182
Autor:
John D. Gordan, Frank Dombrowski, Yu Qiao, Antonio Cossu, Xianqiong Liu, Marina Serra, Shanshan Zhang, Jingxiao Wang, Antonio Cigliano, Haichuan Wang, Alberto Porcu, Silvia Ribback, Kirsten Utpatel, Matthias Evert, Rosa Maria Pascale, Xinhua Song, Xin Chen, Li Che, Diego F. Calvisi, Hongbo Hu, Maria G. Pilo
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research, vol 25, iss 1
Purpose: Intrahepatic cholangiocarcinoma (ICC) is an aggressive cancer type, lacking effective therapies and associated with a dismal prognosis. Palbociclib is a selective CDK4/6 inhibitor, which has been shown to suppress cell proliferation in many
Autor:
Hongbo Hu, Guang-Xun Li, Joshua D. Liao, Lei Wang, Junxuan Lu, Margot P. Cleary, Yong Zhang, Melissa J.L. Bonorden, Hyo-Jeong Lee
Publikováno v:
Cancer Prevention Research. 2:484-495
Chemoprevention of prostate cancer by second-generation selenium compounds in reference to selenomethionine holds strong promise to deal with the disease at the root. Here we used the transgenic adenocarcinoma mouse prostate (TRAMP) model to establis