Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Basu, Bristi"'
Autor:
Yap, Timothy A, Kristeleit, Rebecca, Michalarea, Vasiliki, Pettitt, Stephen J, Lim, Joline SJ, Carreira, Suzanne, Roda, Desamparados, Miller, Rowan, Riisnaes, Ruth, Miranda, Susana, Figueiredo, Ines, Rodrigues, Daniel Nava, Ward, Sarah, Matthews, Ruth, Parmar, Mona, Turner, Alison, Tunariu, Nina, Chopra, Neha, Gevensleben, Heidrun, Turner, Nicholas C, Ruddle, Ruth, Raynaud, Florence I, Decordova, Shaun, Swales, Karen E, Finneran, Laura, Hall, Emma, Rugman, Paul, Lindemann, Justin PO, Foxley, Andrew, Lord, Christopher J, Banerji, Udai, Plummer, Ruth, Basu, Bristi, Lopez, Juanita S, Drew, Yvette, De Bono, Johann S
Preclinical studies have demonstrated synergy between PARP and PI3K/AKT pathway inhibitors in BRCA1 and BRCA2 (BRCA1/2)-deficient and BRCA1/2-proficient tumors. We conducted an investigator-initiated phase I trial utilizing a prospective intrapatient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d965350921fdb45cf7f96f6c6697826
https://www.repository.cam.ac.uk/handle/1810/306749
https://www.repository.cam.ac.uk/handle/1810/306749
Autor:
Susana Banerjee, Vasiliki Michalarea, Joo Ern Ang, Alvaro Ingles Garces, Andrea Biondo, Ionut-Gabriel Funingana, Martin Little, Ruth Ruddle, Florence Raynaud, Ruth Riisnaes, Bora Gurel, Sue Chua, Nina Tunariu, Joanna C. Porter, Toby Prout, Mona Parmar, Anna Zachariou, Alison Turner, Ben Jenkins, Stuart McIntosh, Ed Ainscow, Anna Minchom, Juanita Lopez, Johann de Bono, Robert Jones, Emma Hall, Natalie Cook, Bristi Basu, Udai Banerji
Publikováno v:
Clinical Cancer Research. 28:4634-4641
Purpose: CT900 is a novel small molecule thymidylate synthase inhibitor that binds to α-folate receptor (α-FR) and thus is selectively taken up by α-FR–overexpressing tumors. Patients and Methods: A 3+3 dose escalation design was used. During do
Autor:
Nagy A. Habib, Emilio Sanseviero, Madhava Pai, Debashis Sarker, Ayumi Hashimoto, Daniel H. Palmer, Mikael H. Sodergren, Vikash Reebye, Jeff Evans, Shahid A. Khan, Nina Raulf, Y.T. Ma, Andrew V. Kossenkov, Robert Habib, David J. Pinato, Ruth Plummer, Cheng E. Chee, John J. Rossi, Kai-Wen Huang, Naouel Elasri, Sheba Jarvis, Duncan Spalding, Jenni Vasara, Dmitry I. Gabrilovich, Bristi Basu, Adeline Reynaud, Mark Cobbold, Anna Martirosyan, Tim Meyer, Rohini Sharma, Pinelopi Andrikakou
Publikováno v:
Clin Cancer Res
Purpose: To evaluate the mechanisms of how therapeutic upregulation of the transcription factor, CCAAT/enhancer-binding protein alpha (C/EBPα), prevents tumor progression in patients with advanced hepatocellular carcinoma (HCC) and in different mous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8ca2967f716b56bccb65db914fa7bfa
https://www.repository.cam.ac.uk/handle/1810/349249
https://www.repository.cam.ac.uk/handle/1810/349249