Zobrazeno 11 - 20
of 12 818
pro vyhledávání: ''
Autor:
Xuemei Zhu, Joseph K. Lim, Melinda L. Irwin, Brenda Y. Hernandez, Herbert Yu, Xiaomei Ma, Harvey A. Risch, Lingeng Lu, Robert S. Brown, Zhanwei Wang, Karen Pawlish, Antoinette M. Stroup, Linda L. Wong, Tamar H. Taddei
Publikováno v:
Cancer Epidemiol Biomarkers Prev
Background: Gut microbial alterations have been linked to chronic liver disease and hepatocellular carcinoma (HCC). The role of the oral microbiome in liver cancer development has not been widely investigated. Methods: Bacterial 16S rRNA sequences we
Autor:
Paola Suarez-Meade, Rachel Sarabia-Estrada, Karim ReFaey, Paula Schiapparelli, Cesar A. Garcia, Matija Snuderl, Mieu Brooks, Erik H. Middlebrooks, Sujan Kumar Mondal, Mark E. Jentoft, Adip G. Bhargav, Hugo Guerrero-Cazares, Natanael Zarco, Alfredo Quinones-Hinojosa, Anna Carrano
Publikováno v:
Mol Cancer Ther
Glioblastoma (GBM) is the most common primary brain cancer in adults where tumor cell heterogeneity and sex differences influence clinical outcomes. Here, we functionally characterize three male and three female patient-derived GBM cell lines, identi
Autor:
Andriy Zhylko, Marta Klopotowska, Zofia Pilch, Malgorzata Firczuk, Aleksander Slusarczyk, Malgorzata Bajor, Herman Netskar, Dariusz Plewczynski, Karl-Johan Malmberg, Agnieszka Goral, Iwona Baranowska, Agnieszka Graczyk-Jarzynka, Blanka Sharma, Kuba Retecki, Joanna Domagala, Radoslaw Zagozdzon, Mieszko Lachota, Michal Lazniewski, Karolina Soroczynska, Madison N. Temples, Katsiaryna Marhelava, Agnieszka Kraft, Kavita Ramji, Marta Krawczyk, Magdalena Winiarska
Publikováno v:
Cancer Immunology Research. 10:228-244
Oxidative stress, caused by the imbalance between reactive species generation and the dysfunctional capacity of antioxidant defenses, is one of the characteristic features of cancer. Here, we quantified hydrogen peroxide in the tumor microenvironment
Is Hodgkin Lymphoma Associated with Hepatitis B and C Viruses? A Systematic Review and Meta-analysis
Publikováno v:
Cancer Epidemiology, Biomarkers & Prevention. 30:2167-2175
Background: Apart from the Epstein–Barr virus (EBV), the etiology of the hematologic malignancy Hodgkin lymphoma (HL) is not well defined. Hepatitis B virus (HBV) and hepatitis C virus (HCV) are associated with some lymphoproliferative diseases wit
Autor:
Jinying Shen, Yujie Zhao, Linhai Zhong, Tianhui Hu, Xiong Chen, Xiaolin Xu, Daxuan Wang, Yan-yan Zhan, Xiaoting Hong, Hanwei Cao, Yitong Zhou, Jianben Wu, Ying Lin, Wenqing Zhang, Jihuan Hou
Publikováno v:
Cancer Research. 81:5904-5918
Invasive mucinous lung adenocarcinoma (IMA) is a subtype of lung adenocarcinoma with a strong invasive ability. IMA frequently carries "undruggable" KRAS mutations, highlighting the need for new molecular targets and therapies. Nuclear receptor HNF4
Autor:
Emad A. Rakha, Ying Zhang, Hamid Band, Lulu Yu, Dhananjaya Pal, Mohsin Raza, Zhi-Ming Zheng, Vimla Band, M. Jordan Rowley, Achyuth Kalluchi, Bhopal Mohapatra, Michel M. Ouellette, Sameer Mirza, Irfana Saleem, Fang Qiu, Mansour Alsaleem, Alexei Lobanov
Publikováno v:
Mol Cancer Res
High-risk human papillomaviruses (HPV), exemplified by HPV16/18, are causally linked to human cancers of the anogenital tract, skin, and upper aerodigestive tract. Previously, we identified Ecdysoneless (ECD) protein, the human homolog of the Drosoph
Autor:
Li Ji, Jingjing Wang, Lingli Gong, Yaling Hu, Jian Zou, Ying Yin, Xusheng Yang, Yingdi Jiang, Zhenhao Zhang, Zhening Pu, Bo Zhang
Publikováno v:
Molecular Cancer Research. 20:92-101
Previous studies have demonstrated that glucocorticoid receptor β (GRβ) functions as an oncoprotein, regulating the malignant phenotypes and stem-like cell maintaining in human glioblastoma (GBM). Of the glucocorticoid receptor (GR) isoforms, GRβ
Autor:
Wenyi Fan, Dongxin Lin, Shaosen Zhang, Weiling Liu, Wen Tan, Xuan Zhao, Ai Lin, Xiangjie Niu, Chen Wu, Ping Ji, Yanxia Sun, Eric J. Wagner, Yamei Chen, Yachen Liu, Chuanwang Miao
Publikováno v:
Cancer Research. 81:5638-5651
The majority of human genes have multiple polyadenylation sites, which are differentially used through the process of alternative polyadenylation (APA). Dysregulation of APA contributes to numerous diseases, including cancer. However, specific genes
Autor:
Richa Gupta, Sima Zacharek, Robert S. Meehan, Micaela Morgado, Angelo Porciuncula, Kurt A. Schalper, Kostas N. Syrigos, Joshua Frederick
Publikováno v:
Clin Cancer Res
Purpose: To evaluate the tissue distribution and clinical significance of OX40 and OX40L in human non–small cell lung cancer (NSCLC). Experimental Design: Using multiplexed quantitative immunofluorescence, we conducted simultaneous and localized me
Autor:
Sebastian Bauer, Steven Attia, Hans Gelderblom, Peter Reichardt, Gina Z. D'Amato, Michael Heinrich, Julie Meade, Patrick Schöffski, Suzanne George, John Zalcberg, Margaret von Mehren, Jean-Yves Blay, Rodrigo Ruiz-Soto, Ping Chi, César Serrano, Robin L. Jones, Ying Su
Publikováno v:
Clinical Cancer Research, 27(23), 6333-6342. AMER ASSOC CANCER RESEARCH
Scientia
Scientia
Purpose: Most patients with gastrointestinal stromal tumor (GIST) have activating mutations in KIT/PDGFRA and are initially responsive to tyrosine kinase inhibitors (TKI). The acquisition of secondary mutations leads to refractory/relapsed disease. T