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pro vyhledávání: '"Allison Berger"'
Autor:
Anindya Dutta, Amir A. Jazaeri, Etsuko Shibata, Jonghoon Park, Michael Milhollen, Susan C. Modesitt, Allison Berger, Mark R. Conaway, Jennifer Bryant, Peter G. Smith
Publikováno v:
Molecular Cancer Therapeutics. 12:1958-1967
The nearly ubiquitous development of chemoresistant disease remains a major obstacle against improving outcomes for patients with ovarian cancer. In this investigation, we evaluated the preclinical activity of MLN4924, an investigational inhibitor of
Autor:
Mark R. Conaway, Susan C. Modesitt, Jonghoon Park, Jennifer Bryant, Peter G. Smith, Michael Milhollen, Allison Berger, Amir A. Jazaeri, Anindya Dutta, Etsuko Shibata
Publikováno v:
Cancer Research. 73:3380-3380
Purpose: The objective of this investigation was to evaluate the preclinical activity of MLN4924, an investigational inhibitor of the NEDD8-activating enzyme, against chemoresistant and chemosensitive ovarian cancer cells. ExperimentalDesign: Efficac