Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Hariharan Easwaran"'
Autor:
Stephen B. Baylin, Subhojit Sen, Leslie Cope, Leander Van Neste, Gayle Jeannette Pageau, Kornel E. Schuebel, Hariharan Easwaran, Jeanne B. Lawrence, Helai P. Mohammad, James G. Herman
Publikováno v:
Cancer Research. 70:8015-8024
Aberrant promoter DNA-hypermethylation and repressive chromatin constitutes a frequent mechanism of gene inactivation in cancer. There is great interest in dissecting the mechanisms underlying this abnormal silencing. Studies have shown changes in th
Autor:
Byunghak Kang, Jean Pierre J. Issa, Julie In, Stephen B. Baylin, Nicholas C. Zachos, David L. Huso, Hariharan Easwaran, Shinji Maegawa
Publikováno v:
Cancer Research. 76:4273-4273
Herein, we report a model for how BRAF mutations, in contrast to KRAS mutations, specifically associate with and induce, in mouse colon organoids without a microenvironment, the phenotype of human sporadic right-sided colon adenocarcinomas (COAD). Th