Zobrazeno 1 - 7
of 7
pro vyhledávání: '"59"'
Autor:
M Melé, Serafin Morales, Noelia Martínez, Jordi Canes, Begoña Bermejo, I Garau, Paolo Nuciforo, Patricia Villagrasa, Maria Jose Echarri, Antonia Perelló, Barbara Adamo, Blanca Gonzalez-Farre, Silvia Vazquez, Tomás Pascual, Xavier Gonzalez, Santiago Escrivá-de-Romaní, Patricia Galván, Sonia Pernas, Eva Ciruelos, Mafalda Oliveira, D. Martinez, Javier Cortes, Laia Paré, Alvaro Montaño, Aleix Prat, Eduardo Martínez, Estela Vega, Luis Manso
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
instname
CLINICAL CANCER RESEARCH
r-FHPC. Repositorio Institucional de Producción Científica de la Fundación del Hospital Provincial de Castellón
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
instname
CLINICAL CANCER RESEARCH
r-FHPC. Repositorio Institucional de Producción Científica de la Fundación del Hospital Provincial de Castellón
Purpose:To assess palbociclib in combination with trastuzumab with or without endocrine therapy in patients with HER2-positive advanced breast cancer.Patients and Methods:PATRICIA is a prospective, open-label, multicenter phase II trial. Patients had
Autor:
Gail S. Wright, L Finney, Laura M. DeBusk, A Mani, D. A. Yardley, John D. Hainsworth, H. A. Burris, Mythili Shastry, Lowell L. Hart, Patrick S. Ward, P.K. Chandra, S Guo
Publikováno v:
Cancer Research. 76:P1-14
Background: Eribulin mesylate (Er) is a non-taxane inhibitor of microtubule growth that results in G2-M cell cycle arrest, disruption of normal mitotic spindles and apoptosis. Er demonstrated an overall survival (OS) but not progression free survival
Autor:
P García, J. Florián, P. Zamora, Sonia Servitja, A. Velasco, M. A. Seguí, E Artime, L. De Paz, J de la Haba, Eduardo Martínez, Jose Manuel Perez Garcia, Ana Santaballa, J. Rodríguez-Villanueva, I Chacón, Y Plata, I Garau
Publikováno v:
Cancer Research. 76:P3-07
BACKGROUND: Currently available therapeutic armamentarium for locally advanced and/or metastatic breast cancer (LA/MBC) allows an increasing tailored approach for each of the major tumor immunophenotypes. Nevertheless, there is scarce information abo
Autor:
Maren K. Levin, Y Daoud, Cynthia Osborne, Joyce A. O'Shaughnessy, Karolina Palucka, D Grosser, MA Mardones
Publikováno v:
Cancer Research. 77:P2-04
Background: Breast cancer (BC) evolution is influenced by tumor microenvironment. Presence of CD8+ cytotoxic T lymphocytes (TILs) has been proposed as surrogate marker of adaptive immune response, and programmed death ligand-1 (PD-L1) is a negative r
Autor:
Rebecca R. Hozak, Carla Visseren-Grul, Sanjay Popat, Santiago Ponce Aix, Makoto Nishio, Kazuto Nishio, Sameera R. Wijayawardana, Kazuhiko Nakagawa, Edward B. Garon, John V. Heymach, Luis Paz-Ares, Martin Reck, Silvia Novello
Publikováno v:
Cancer Research. 80:CT215-CT215
RELAY (NCT02411448) showed a superior progression free survival benefit with RAM+ERL versus (v) PBO+ ERL (mPFS 19.4 vs 12.4mo, HR 0.59, p-value TablePts (≥2 in either treatment group) with treatment emergent alterationsaPop1bPop2bGene NameRAM+ERL (
Autor:
Beverly Moy, Dejan Juric, SJ Isakoff, Giuliana Malvarosa, Tanya Keenan, Laura Spring, Hannah Park, Maureen Beeler, Andrzej Niemierko, Leif W. Ellisen, Aditya Bardia
Publikováno v:
Cancer Research. 78:P2-02
Introduction: Genomic profiling of circulating tumor DNA (ctDNA) allows non-invasive monitoring of tumor genetic changes and molecular heterogeneity. In addition to actionable mutations, mutational landscape derived from ctDNA could provide a better
Autor:
Muhammed Salim, Linda Hagerman, Mark Clemons, Karen A. Gelmon, Susan Dent, Sukhbinder Dhesy-Thind, Mihaela Mates, Vanessa Bernstein, Dongsheng Tu, Xinni Song, Lawrence Panasci, Lesley Seymour, Susan Ellard
Publikováno v:
Cancer Research. 77:CT131-CT131
Background: Pelareorep is a Dearing strain of reovirus serotype 3, with demonstrated in vitro and in vivo activity in many cancers and synergistic cytotoxic activity with microtubule targeting agents, including taxanes. This study was designed to det