Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Jiang A"'
Autor:
Xueliang Gao, Yubao Wang, Caroline F. Ribeiro, Cherubin Manokaran, Hyeyoun Chang, Thanh Von, Silvia Rodrigues, Onur Cizmecioglu, Shidong Jia, Manav Korpal, Joshua M. Korn, Zhigang Wang, Fabienne Schmit, Lan Jiang, Raymond Pagliarini, Yi Yang, Isha Sethi, Sabina Signoretti, Guo-Cheng Yuan, Massimo Loda, Jean J. Zhao, Thomas M. Roberts
Publikováno v:
Molecular Cancer Research
Mol Cancer Res
Mol Cancer Res
A common outcome of androgen deprivation in prostate cancer therapy is disease relapse and progression to castration-resistant prostate cancer (CRPC) via multiple mechanisms. To gain insight into the recent clinical findings that highlighted genomic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::417496ddabb9a0b6f08cefe8db0057fc
https://hdl.handle.net/11693/111708
https://hdl.handle.net/11693/111708
Autor:
Ping Zhang, Enric Domingo, Daniel Ebner, Marsha D. Wallace, Natasha Sahgal, Hannah Carter, Andrew Protheroe, Philipp Harald Richter, Paul D.P. Pharoah, Janet Shipley, Val Millar, Lingyun Xiong, Katherine A. Brown, Rick Jansen, Svanhild Nornes, Jorge Zeron-Medina, Anderson J. Ryan, Ian Tomlinson, Joanna Selfe, Isaac Kitchen-Smith, Elisabeth E. Bond, Sarah P. Blagden, Chey Loveday, David Sims, Sarah De Val, Tim Maughan, Douglas A. Bell, Samantha Moore, Gareth L. Bond, Meghana Pagadala, Yanyan Jiang, Claire Palles, Giovanni Stracquadanio, Siddhartha Kar, Xuting Wang, Mirvat Surakhy, Clare Turnbull, Lukasz Filip Grochola
Publikováno v:
Cancer Res
Cancer Research, 81(7), 1667-1680. American Association for Cancer Research Inc.
Cancer research, vol 81, iss 7
Zhang, P, Kitchen-Smith, I, Xiong, L, Stracquadanio, G, Brown, K, Richter, P, Wallace, M, Bond, E, Sahgal, N, Moore, S, Nornes, S, De Val, S, Surakhy, M, Sims, D, Wang, X, Bell, D A, Zeron-Medina, J, Jiang, Y, Ryan, A, Selfe, J, Shipley, J, Kar, S, Pharoah, P, Loveday, C, Jansen, R, Grochola, L F, Palles, C, Protheroe, A, Millar, V, Ebner, D, Pagadala, M, Blagden, S P, Maughan, T, Domingo, E, Tomlinson, I P M, Turnbull, C, Carter, H & Bond, G L 2021, ' Germline and somatic genetic variants in the p53 pathway interact to affect cancer risk, progression and drug response ', Cancer Research . https://doi.org/10.1158/0008-5472.CAN-20-0177
Zhang, P, Kitchen-Smith, I, Xiong, L, Stracquadanio, G, Brown, K, Richter, P H, Wallace, M D, Bond, E, Sahgal, N, Moore, S, Nornes, S, De Val, S, Surakhy, M, Sims, D, Wang, X, Bell, D A, Zeron-Medina, J, Jiang, Y, Ryan, A J, Selfe, J L, Shipley, J, Kar, S, Pharoah, P D P, Loveday, C, Jansen, R, Grochola, L F, Palles, C, Protheroe, A, Millar, V, Ebner, D V, Pagadala, M, Blagden, S P, Maughan, T S, Domingo, E, Tomlinson, I, Turnbull, C, Carter, H & Bond, G L 2021, ' Germline and somatic genetic variants in the p53 pathway interact to affect cancer risk, progression, and drug response ', Cancer Research, vol. 81, no. 7, pp. 1667-1680 . https://doi.org/10.1158/0008-5472.CAN-20-0177
Cancer Research, 81(7), 1667-1680. American Association for Cancer Research Inc.
Cancer research, vol 81, iss 7
Zhang, P, Kitchen-Smith, I, Xiong, L, Stracquadanio, G, Brown, K, Richter, P, Wallace, M, Bond, E, Sahgal, N, Moore, S, Nornes, S, De Val, S, Surakhy, M, Sims, D, Wang, X, Bell, D A, Zeron-Medina, J, Jiang, Y, Ryan, A, Selfe, J, Shipley, J, Kar, S, Pharoah, P, Loveday, C, Jansen, R, Grochola, L F, Palles, C, Protheroe, A, Millar, V, Ebner, D, Pagadala, M, Blagden, S P, Maughan, T, Domingo, E, Tomlinson, I P M, Turnbull, C, Carter, H & Bond, G L 2021, ' Germline and somatic genetic variants in the p53 pathway interact to affect cancer risk, progression and drug response ', Cancer Research . https://doi.org/10.1158/0008-5472.CAN-20-0177
Zhang, P, Kitchen-Smith, I, Xiong, L, Stracquadanio, G, Brown, K, Richter, P H, Wallace, M D, Bond, E, Sahgal, N, Moore, S, Nornes, S, De Val, S, Surakhy, M, Sims, D, Wang, X, Bell, D A, Zeron-Medina, J, Jiang, Y, Ryan, A J, Selfe, J L, Shipley, J, Kar, S, Pharoah, P D P, Loveday, C, Jansen, R, Grochola, L F, Palles, C, Protheroe, A, Millar, V, Ebner, D V, Pagadala, M, Blagden, S P, Maughan, T S, Domingo, E, Tomlinson, I, Turnbull, C, Carter, H & Bond, G L 2021, ' Germline and somatic genetic variants in the p53 pathway interact to affect cancer risk, progression, and drug response ', Cancer Research, vol. 81, no. 7, pp. 1667-1680 . https://doi.org/10.1158/0008-5472.CAN-20-0177
Insights into oncogenesis derived from cancer susceptibility loci (SNP) hold the potential to facilitate better cancer management and treatment through precision oncology. However, therapeutic insights have thus far been limited by our current lack o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af3484e3e3aa599b5ecb1278c95e8894
https://ora.ox.ac.uk/objects/uuid:5e165644-cc00-4d74-8fff-6e62725c1cfc
https://ora.ox.ac.uk/objects/uuid:5e165644-cc00-4d74-8fff-6e62725c1cfc
Autor:
Qixia Xu, Min Qian, Shenjun Li, Liu Cao, Jing Jiang, Boyi Zhang, Qilai Long, Eric Lam, Y. Eugene Chin, Xuefeng Dou, Liu Han, Jianming Guo, Yu Sun, Yannasittha Jiramongkol
Cellular senescence is a potent tumor-suppressive program that prevents neoplastic events. Paradoxically, senescent cells develop an inflammatory secretome, termed the senescence-associated secretory phenotype, which is implicated in age-related path
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de1a7b161a2b0873599bdc3b107c21d1
http://hdl.handle.net/10044/1/79434
http://hdl.handle.net/10044/1/79434
Autor:
Chen, Xian, Low, Kwang Hui, Alexander, Angela, Jiang, Yufeng, Karakas, Cansu, Hess, Kenneth R., Carey, Jason P.W., Bui, Tuyen, Vijayaraghavan, Smruthi, Evans, Kurt W., Yi, Min, Ellis, D. Christian, Cheung, Kwok-Leung, Ellis, Ian O., Fu, Siqing, Meric-Bernstam, Funda, Hunt, Kelly K., Keyomarsi, Khandan
Purpose: Poor prognosis in triple-negative breast cancer (TNBC) is due to an aggressive phenotype and lack of biomarker-driven targeted therapies. Overexpression of cyclin E and phosphorylated-CDK2 are correlated with poor survival in TNBC patients,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::8143a0418be0e67b2dd2c0e39bc85c29
Autor:
Wen Guo Jiang, Serena Tommasini-Ghelfi, Andrew D. Westwell, Charlotte L. Bevan, Sahar Kandil, Gilberto S. Almeida, D. Alwyn Dart
Prostate cancer often develops antiandrogen resistance, possibly via androgen receptor (AR) mutations, which change antagonists to agonists. Novel therapies with increased anticancer activity, while overcoming current drug resistance are urgently nee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::276b99dc1243f2281e01ecd1a7eabdd1
http://hdl.handle.net/10044/1/61165
http://hdl.handle.net/10044/1/61165
Hairy and Enhancer-of-split related with YRPW motif (Hey) transcription factors are important regulators of stem cell embryogenesis. Clinical relevance shows that they are also highly expressed in malignant carcinoma. Recent studies have highlighted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da5508644166d81c9850fe2520ebf523
Autor:
Hannes Vogel, Daniela Kenzelmann Broz, Stephano S. Mello, Dadi Jiang, Colleen A. Brady, Laura D. Attardi, Eunice J. Park
Publikováno v:
Genetics.
The essential role of p53 in tumor suppression is highlighted by the observations that p53 is mutated in over half of human cancers and that p53-null mice are highly predisposed to developing cancer. Although p53 is thought to suppress cancer by indu
Publikováno v:
Cancer Research. Aug2011, Vol. 71 Issue 16, p5364-5364. 1/4p.
Autor:
Ying Meei Tan1, Dahui Sun1, Weijian Jiang1, Klotz-Noack, Kathleen1, Vashisht, Ajay A.2, Wohlschlegel, James2, Widschwendter, Martin3, Spruck, Charles1 cspruck@sanfordburnham.org
Publikováno v:
Cancer Research. 4/1/2014, Vol. 74 Issue 7, p2006-2014. 9p.
Autor:
Xuesong Zhao1,2, Ponomaryov, Tatyana1,2,3, Ornell, Kimberly J.1,2, Pengcheng Zhou1,2, Dabral, Sukriti K.1,2, Pak, Ekaterina1,2, Wei Li4, Atwood, Scott X.5, Whitson, Ramon J.5, Chang, AnneLynn S.5, Jiang Li5, Oro, Anthony E.5, Chan, Jennifer A.6, Kelleher, Joseph F.7, Segal, Rosalind A.1,2 rosalind_segal@dfci.harvard.edu
Publikováno v:
Cancer Research. 9/1/2015, Vol. 75 Issue 17, p3623-3635. 13p.