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Publikováno v:
Annals of Palliative Medicine. 11:818-826
Until present, late-stage gastric cancer (GC) remains a refractory disease featured with poor prognosis. However, the upcoming era of immunotherapy turns situations around. Programmed death-1 receptor (PD-1)/programmed death-ligand 1 (PD-L1) signalin
Autor:
Zhen Cai, Yanbin Gao, Wen-Jing Zhao, Yue-Fen Wang, Cun Shen, Xin-Can Jiang, Yuan Meng, Fang-Qiang Cui
Publikováno v:
Annals of Palliative Medicine. 10:12921-12936
Background Diabetic nephropathy (DN) is the leading cause of end-stage renal disease (ESRD). Podocyte epithelial-esenchymal transformation (EMT) induced by the activated Wnt/β-catenin pathway plays a key role in DN. Tang-Shen-Ning (TSN), a Chinese h
Publikováno v:
Annals of Palliative Medicine. 10:8499-8505
Mature cystic teratomas (MCTs), also known as dermoid cysts, are the most common ovarian germ cell tumors and the most common ovarian neoplasms in patients younger than 20 years. MCTs mainly appear as pelvic masses that are made up of different types
Publikováno v:
Annals of Palliative Medicine. 10:8437-8447
This study aimed to report the clinical characteristics of penicilliosis marneffei (PSM) in three children negative to HIV. Three children were diagnosed with PSM in the Department of Emergency Medicine, Hunan Children's Hospital between February 201
Publikováno v:
Annals of Palliative Medicine. 10:8391-8395
Intestinal metaplasia (IM) in the esophagus is considered as a risk factor of subsequent intestinal-type adenocarcinoma based on the classical theory of metaplasia-dysplasia-carcinoma. IM rarely occurs in urinary tract and fewer studies have been rep
Publikováno v:
Quant Imaging Med Surg
Recent progress in immunotherapy provides hope of a complete cure to cancer patients. However, recent studies have reported that only a limited number of cancer patients with a specific immune status, known as “cold tumor”, can benefit from a sin
Publikováno v:
Transl Pediatr
Objective Infants with extrauterine growth restriction (EUGR) experience significant postnatal growth restriction in the first week after birth, which indicates a failure of energy absorption. This study aimed to determine the different intestinal mi
Publikováno v:
J Thorac Dis
BACKGROUND: Histologic subtypes were considered prognostic factors in early-stage lung adenocarcinoma in the 7(th) edition of the tumor node metastasis (TNM) staging system (TNM-7). However, the T-staging system has changed and now measures only the
Autor:
Freyja-Maria Smolle-Juettner, Elisabeth Smolle, Jörg Lindenmann, Valentin Taucher, Martin Pichler
Publikováno v:
Transl Lung Cancer Res
Lung cancer ranks first as the cause of cancer-associated deaths gobally. The American Cancer Society estimates for 228,820 new cases and 135,720 deaths from lung cancer in the United States for the year 2020. Targeted treatment options have rapidly
Autor:
Xiao-Fei Zhang, Xiaolin Ge, Rui-Yan Wu, Hui Chen, Zhaoyue Zhang, Xinchen Sun, Liping Xu, Hongyan Cheng, Ming Liu, Hong-Cheng Zhu
Publikováno v:
Transl Lung Cancer Res
BACKGROUND: In recent years, immunotherapy has made great progress, and the regulatory role of epigenetics has been verified. However, the role of 5-methylcytosine (m(5)C) in the tumor microenvironment (TME) and immunotherapy response remains unclear