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Autor:
Muzna Ali Khattak, Ismail Khan, Fahim Ullah, Akhtar Aman, Zafar Iqbal, Mehboob Alam, Sumaira Irum Khan, Mirina Sakhi, Abad Khan
Publikováno v:
Tropical Journal of Pharmaceutical Research; Vol. 20 No. 9 (2021); 1949-1959
Purpose: To develop a simple, novel, sensitive and rapid reverse phase high performance liquid chromatographic method for simultaneous determination of paclitaxel, sorafenib and omeprazole in standard solutions and spiked human plasma and its applica
Publikováno v:
Tropical Journal of Pharmaceutical Research; Vol. 20 No. 9 (2021); 1887-1893
Purpose: To investigate the effects of leflunomide (Lef) on inflammatory response and apoptosis after myocardial infarction, and to explore its molecular mechanisms of action.Methods: H2O2 and H9c2 cells were used to establish myocardial cell injury
Publikováno v:
Tropical Journal of Pharmaceutical Research. 18:2133-2138
Purpose: To investigate the effect of resveratrol (RSV) on bortezomib (BTZ)-resistant multiple myeloma (MM) cells, and to elucidate the underlying mechanism of action. Methods: H929 cell lines were exposed to BTZ for 8 months to establish BTZ-resista
Publikováno v:
Tropical Journal of Pharmaceutical Research. 18:2095-2100
Purpose: To determine the antidiabetic effect of methanol extract of Plectranthus lanuginosus leaves in streptozotocin-induced hyperglycemic (HGD) rats. Methods: P. lanuginosus leaves were collected from Saad Medhas, Al Baha, Kingdom of Saudi Arabia.
Autor:
Ning Sun, Chenchen Li, Yun Zhou, Lei Xia, Xiaoming Wang, Dongfeng Wang, Renhong Guo, Yan Zhang
Publikováno v:
Tropical Journal of Pharmaceutical Research. 18:1993-1998
Purpose: To study the effectiveness and safety of apatinib as second-line treatment for advanced pancreatic cancer (APC) in a Chinese tertiary cancer hospital. Methods: Two groups of APC patients who received treatment with single-agent or two-drug c
Publikováno v:
Tropical Journal of Pharmaceutical Research. 18:1909-1912
Purpose: To evaluate the healing effect of Platycodon grandiflorus (Jacq.). extract (PGE) on experimental burn wounds in rats. Methods: Rats were randomly divided into four groups of eight rats each: control group, silver sulfadiazine (SSD)-treated g
Publikováno v:
Tropical Journal of Pharmaceutical Research. 18:1799-1804
Purpose: To study the effect of bazedoxifene on the expressions of vascular endothelial growth factor (VEGF), soluble vascular endothelial growth factor receptor 2 (sVEGFR2), cyclooxygenase synthase 2 (COX-2) and inflammatory factors in a rat endomet
Publikováno v:
Tropical Journal of Pharmaceutical Research. 18:1519-1526
Purpose: To investigate the mechanism of action of Klebsiella pneumoniae (Kpn) resistance to carbapenem. Methods: The susceptibility of six Klebsiella pneumoniae strains to antibiotics was determined using KB assay. Six isolated strains which were re
Autor:
Linlin Liu, Songnian Liang
Publikováno v:
Tropical Journal of Pharmaceutical Research. 18:1455-1460
Purpose: To investigate the anticancer effects of sparteine against human cervical cancer. Methods: Cell viability was determined by CCK8 assay, while 4′, 6-diamidino-2-phenylindole (DAPI) staining was used for determination of apoptosis. Cell cycl
Autor:
Priyo Hadi, Indi Mazaya Syarifah, Adiastuti Endah Parmadiati, Meircurius Dwi Condro Surboyo, Desiana Radithia, Diah Savitri Ernawati, Shiffin Devi Mardiyana, Hening Tuti Hendarti, Fatma Yasmin Mahdani
Publikováno v:
Tropical Journal of Pharmaceutical Research. 18:1427-1433
Purpose: To analyse the potential use of Citrus limon L. Tlekung peel oil in the treatment of traumatic ulcers in diabetic rats based on number of macrophages and transforming growth factor β (TGF-β) expression. Method: Standard steam distillation