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Publikováno v:
Tropical Journal of Pharmaceutical Research. 19:137-145
Purpose: To evaluate the antimalarial effect of Ananas comosus extract and fractions and also to identify the likely bioactive compounds.Method: The fruit peel of the plant was extracted with methanol, and the extract successively fractionated with n
Autor:
Andy R. Opoku, Rebamang A. Mosa, Foluso Oluwagbemiga Osunsanmi, Babatunji Emmanuel Oyinloye, F.O. Shode, Monisola I. Ikhile, Idiat B. Ogunyinka, Godfrey E. Zaharare
Publikováno v:
Tropical Journal of Pharmaceutical Research; Vol 17, No 10 (2018); 1983-1989
Purpose: To investigate the antithrombotic, anticoagulant and antiplatelet activity of betulinic acid (BA) and 3β-acetoxybetulinic acid (BAA) from Melaleuca bracteata ‘Revolution Gold’. Methods: Betulinic acid was isolated from the ethyl acetate
Publikováno v:
Tropical Journal of Pharmaceutical Research; Vol 17, No 6 (2018); 1073-1080
Purpose : To evaluate the effect of Coscinium fenestratum (CF) crude extract on hypertension in animal models. Methods : Dichloromethane (DCM), ethyl acetate (EA), and butanol (BuOH) extracts were obtained by fractionation from the crude methanol ext
Publikováno v:
Tropical Journal of Pharmaceutical Research. 11
Purpose: To investigate the effect of ethyl acetate extract of S. striata on pro-inflammatory production by macrophages. Methods: Mouse peritoneal macrophages were cultured in solvent either alone or with 2 µg/ml lipopolysaccaride (LPS) with/without
Autor:
Angie Herrera, Juan M. Pérez, Wilson Cardona, Diana L. Muñoz, Fernando Alzate, Sara M. Robledo
Publikováno v:
Tropical Journal of Pharmaceutical Research. 15:973
Purpose: To evaluate the leishmanicidal and cytotoxic activity of alcohol and non-alcohol extracts and saponins from Ilex laurina . Methods: Extracts were obtained by percolation with solvents of different polarities: hexane, dichloromethane, ethyl a
In vitro Studies on Anti-diabetic and Anti-ulcer Potentials of Jatropha gossypifolia (Euphorbiaceae)
Autor:
Irshad Ahmad, M. Shoaib Ali Gill, M Nabeel Shahid, Hammad Saleem, Muhammad Faisal Nadeem, Kashif Barkat, Mussarat Ashraf
Publikováno v:
Tropical Journal of Pharmaceutical Research. 15:121
Purpose: To evaluate α-glucosidase and α-chymotrypsin enzyme inhibitory activity of Jatropha gossypifolia as a probable remedy for the management of diabetes and ulcer.Methods: Different extracts and fractions of the root, leaf and stem bark of the
Publikováno v:
Tropical Journal of Pharmaceutical Research. 14:1445
Purpose: To investigate the hypoglycaemic activity of various extracts of the aerial part of Acalypha fruticosa in normal rabbits. Methods: The rabbits were randomly assigned to 8 groups (n = 3) and treated with a single oral dose. Group 1 served as
Publikováno v:
Tropical Journal of Pharmaceutical Research; Vol 9, No 6 (2010)
Purpose : To establish the method for the analysis of rifampin quinone and hydrazone in fixeddose combination tablets (FDC) containing rifampicin with or without sodium ascorbate as an additive. Methods : The International Pharmacopoeial (IP) method
Publikováno v:
Tropical Journal of Pharmaceutical Research; Vol 8, No 3 (2009)
Purpose: The objective of the study was to investigate the ethyl acetate extract of Morinda morindoides (Baker) Milne-Redh (Rubiaceae) (MM-EA) properties against experimental diarrheoa induced by castor oil in albino Wistar rats. Methods: The ethyl a
Autor:
Lamees A. BenSaad, Kah Hwi Kim
Publikováno v:
Tropical Journal of Pharmaceutical Research; Vol 14, No 1 (2015); 87-93
Purpose: To investigate the active fraction of pomegranate fruit extract and screen it for analgesic activity.Methods: The analgesic activity of pomegranate ethyl acetate fraction (EtOAc) was examined using three models of pain: writhing, hot tail fl