Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Yuexin Xu"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Tumor-associated endothelial cells (TECs) are crucial mediators of immune surveillance and immune escape in the tumor microenvironment (TME). TECs driven by angiogenic growth factors form an abnormal vasculature which deploys molecular machinery to s
Externí odkaz:
https://doaj.org/article/260e213f809045e5ad192a635db49c20
Autor:
David G. Coffey, Francesco Maura, Edgar Gonzalez-Kozlova, J. Javier Diaz-Mejia, Ping Luo, Yong Zhang, Yuexin Xu, Edus H. Warren, Travis Dawson, Brian Lee, Hui Xie, Eric Smith, Amanda Ciardiello, Hearn J. Cho, Adeeb Rahman, Seunghee Kim-Schulze, Benjamin Diamond, Alexander Lesokhin, Dickran Kazandjian, Trevor J. Pugh, Damian J. Green, Sacha Gnjatic, Ola Landgren
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract The role of the immune microenvironment in maintaining disease remission in patients with multiple myeloma (MM) is not well understood. In this study, we comprehensively profile the immune system in patients with newly diagnosed MM receiving
Externí odkaz:
https://doaj.org/article/f009262e72e74d7eb9e4d2fcf98a1f75
Autor:
Chris P. Miller, Megan Fung, Carla A. Jaeger-Ruckstuhl, Yuexin Xu, Edus H. Warren, Shreeram Akilesh, Scott S. Tykodi
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 46, Iss , Pp 100948- (2023)
Metastatic renal cell carcinoma (RCC) remains an incurable disease for most patients highlighting an urgent need for new treatments. However, the preclinical investigation of new therapies is limited by traditional two-dimensional (2D) cultures which
Externí odkaz:
https://doaj.org/article/9a6a0ba591d64c2b98c9db933ac8344f
Publikováno v:
PeerJ, Vol 10, p e14400 (2022)
Background Karyotyping and genome copy number variation sequencing (CNV-seq) are two techniques frequently used in prenatal diagnosis. This study aimed to explore the diagnostic potential of using a combination of these two methods in order to provid
Externí odkaz:
https://doaj.org/article/d8d18c9b35e44c95b4f1d64fb92fc9cf
Autor:
Charlotte A. James, Yuexin Xu, Melissa S. Aguilar, Lichen Jing, Erik D. Layton, Martine Gilleron, Adriaan J. Minnaard, Thomas J. Scriba, Cheryl L. Day, Edus H. Warren, David M. Koelle, Chetan Seshadri
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
CD4 and CD8 co-receptors are routinely used to define distinct functional and phenotypic lineages of T cells. Here the authors show CD4 and CD8 also modulate the functional avidity of the CD1b-restricted response to mycobacterial lipid antigens
Externí odkaz:
https://doaj.org/article/5ffbba8ac40b4631bfdd4ca36548cb97
Autor:
David G. Coffey, Yuexin Xu, Andrea M. H. Towlerton, Marcin Kowanetz, Priti Hegde, Martine Darwish, Mahesh Yadav, Craig Blanchette, Shannon M. Ruppert, Sarah Bertino, Qikai Xu, Andrew Ferretti, Adam Weinheimer, Matthew Hellmann, Angel Qin, Dafydd Thomas, Edus H. Warren, Nithya Ramnath
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Most patients with advanced non-small cell lung cancer (NSCLC) do not achieve a durable remission after treatment with immune checkpoint inhibitors. Here we report the clinical history of an exceptional responder to radiation and anti-program death-l
Externí odkaz:
https://doaj.org/article/0ad62252e9ae47dfa7add7911dd39d72
Autor:
Yuexin Xu, Alicia J. Morales, Andrea M. H. Towlerton, Shreeram Akilesh, Chris P. Miller, Scott S. Tykodi, Edus H. Warren
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Objective responses of metastatic renal cell carcinoma (RCC) associated with systemic immunotherapies suggest the potential for T-cell-mediated tumor clearance. Recent analyses associate clonally expanded T cells present in the tumor at diagnosis wit
Externí odkaz:
https://doaj.org/article/0138d642c53e44d4b870bb69d299c4c9
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 17, Iss 7, Pp 1882-1896 (2021)
In renal-cell carcinoma (RCC), tumor-reactive T-cell responses can occur spontaneously or in response to systemic immunotherapy with cytokines and immune checkpoint inhibitors. Cancer vaccines and engineered T-cell therapies are designed to selective
Externí odkaz:
https://doaj.org/article/fdeb72bf1a044f61940f92e772545845
Autor:
Shiyu Chen, Zhonglin Jia, Ming Cai, Mujie Ye, Dandan Wu, Teng Wan, Bowen Zhang, Peixuan Wu, Yuexin Xu, Yuntao Guo, Chan Tian, Duan Ma, Jing Ma
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Non-syndromic cleft lip and palate (NSCLP) is one of the most common congenital malformations with multifactorial etiology. Although long non-coding RNAs (lncRNAs) have been implicated in the development of lip and palate, their roles in NSCLP are no
Externí odkaz:
https://doaj.org/article/203e1d5edb344a16a97c728e221cc62e
Publikováno v:
Chinese Journal of Lung Cancer, Vol 12, Iss 5, Pp 375-380 (2009)
Background and objective Annexin Ⅱ is a calcium-dependent phosphnolipid-binding proteinthat plays a role in many cellular functions. It has been proven that annexin Ⅱ has been involved in many human cancers.The aim of this study is to examine the
Externí odkaz:
https://doaj.org/article/cd427f3dbe3a4767b280a934292d4dcb