Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Robert Orlando"'
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Ganoderma lucidum (GL), commonly known as “Lingzhi”, is a well-known medicinal mushroom with antioxidant and anti-cancer activity. This study examined the effects of a commercial GL product (GLSF) containing the spore and fruiting body in a 30:8
Externí odkaz:
https://doaj.org/article/fe78b34b4ddd44e2ac8eadc2db4da30e
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 5, p 5058 (2023)
Oral mucositis is a common side effect of cancer treatment, and in particular of treatment with the mTORC1 inhibitor everolimus. Current treatment methods are not efficient enough and a better understanding of the causes and mechanisms behind oral mu
Externí odkaz:
https://doaj.org/article/e389b9dcd262406a87090db1ff8f072a
Autor:
Md Abdullah Shamim, Ayaz Shahid, Pabitra K. Sardar, Steven Yeung, Jeremiah Reyes, Jenny Kim, Cyrus Parsa, Robert Orlando, Jeffrey Wang, Kristen M. Kelly, Frank L. Meyskens, Bradley T. Andresen, Ying Huang
Publikováno v:
Nanomaterials, Vol 13, Iss 5, p 929 (2023)
The R-carvedilol enantiomer, present in the racemic mixture of the chiral drug carvedilol, does not bind to the β-adrenergic receptors, but exhibits skin cancer preventive activity. For skin delivery, R-carvedilol-loaded transfersomes were prepared
Externí odkaz:
https://doaj.org/article/3d025cf03a8f49b5987bc6fd3a863216
Autor:
Ayaz Shahid, Mengbing Chen, Carol Lin, Bradley T. Andresen, Cyrus Parsa, Robert Orlando, Ying Huang
Publikováno v:
Cancers, Vol 15, Iss 3, p 583 (2023)
The current study evaluated the effects of the β-blocker carvedilol on benzo(a)pyrene (B(a)P) and its active metabolite benzo(a)pyrene diol epoxide (BPDE)-induced lung toxicity, inflammation and carcinogenesis and explored the potential mechanisms.
Externí odkaz:
https://doaj.org/article/855f46154bf04520b2a3f47006c31d92
Autor:
Ayaz Shahid, Matthew Huang, Mandy Liu, Md Abdullah Shamim, Cyrus Parsa, Robert Orlando, Ying Huang
Publikováno v:
PLoS ONE, Vol 17, Iss 3, p e0265615 (2022)
The medicinal mushroom Ganoderma lucidum is traditionally used for treating multiple diseases, including cancer. This study examined skin cancer preventive activity of a commercial product containing spore and fruiting body in 30:8 ratio (GLSF). Extr
Externí odkaz:
https://doaj.org/article/691429e566e24f83810faf1defe1b7f0
Autor:
Cyrus Parsa, D.O., Amanda Thompson, Robert Orlando, M.D., Ph.D., Ravin Rupani, M.D., Jin Guo, M.D.
Publikováno v:
Human Pathology: Case Reports, Vol 20, Iss , Pp 200359- (2020)
Chromosomal abnormalities involving 11q23 with Lysine [K]specific MethylTransferase 2A (KMT2A) gene rearrangement are common among children with aggressive acute leukemias. In KMT2A-rearranged adult Acute Lymphoblastic Leukemia (ALL), five translocat
Externí odkaz:
https://doaj.org/article/a347029cc2624be1ace55af8633332bb
Autor:
Cyrus Parsa, D.O, Robert Orlando, M.D., PhD, Krishna Narayanan, M.D., Umakant M. Khetan, M.D., Jin Guo, M.D., Ravin Rupani, M.D.
Publikováno v:
Human Pathology: Case Reports, Vol 18, Iss , Pp - (2019)
Multiple primary malignancies may occur as synchronous or meta-synchronous tumors in 2–17% of patients. Most multiple primary cancers occur in different locations of the same organ or in other organs such as lung, kidney, prostate, and bone. Occurr
Externí odkaz:
https://doaj.org/article/30768c640fac49369772bbf61f6a76a2
Publikováno v:
Colombia Forestal, Vol 15, Iss 2, Pp 227-245 (2012)
This paper proposes a methodology for generating optimal cutting patterns in sawmills operations that minimize waste production. Firstly, a linear programming model was used to generate patterns of feasible and optimal cuts for different diameter cla
Externí odkaz:
https://doaj.org/article/6d0b35da407140d1b63c3bae583ba3c8
Autor:
Mandy M. Liu, Kevin M. Huang, Steven Yeung, Andy Chang, Suhui Zhang, Nan Mei, Cyrus Parsa, Robert Orlando, Ying Huang
Publikováno v:
Nutrients, Vol 9, Iss 3, p 300 (2017)
Exploring traditional medicines may lead to the development of low-cost and non-toxic cancer preventive agents. Si-Wu-Tang (SWT), comprising the combination of four herbs, Rehmanniae, Angelica, Chuanxiong, and Paeoniae, is one of the most popular tra
Externí odkaz:
https://doaj.org/article/5e5cf68148d147559a916d994997844c
Autor:
Jijun Hao, Rachel Lee, Andy Chang, Jeffery Fan, Chantelle Labib, Cyrus Parsa, Robert Orlando, Bradley Andresen, Ying Huang
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e90748 (2014)
The bone morphogenetic protein (BMP) signaling cascade is aberrantly activated in human non-small cell lung cancer (NSCLC) but not in normal lung epithelial cells, suggesting that blocking BMP signaling may be an effective therapeutic approach for lu
Externí odkaz:
https://doaj.org/article/1cf69e5730e246f8a7ad538a3b759c61