Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Robert F. Paulson"'
Autor:
Fenghua Qian, Shaneice K. Nettleford, Jiayan Zhou, Brooke E. Arner, Molly A. Hall, Arati Sharma, Charyguly Annageldiyev, Randy M. Rossi, Diwakar B. Tukaramrao, Deborpita Sarkar, Shailaja Hegde, Ujjawal H. Gandhi, Emily R. Finch, Laura Goodfield, Michael D. Quickel, David F. Claxton, Robert F. Paulson, K. Sandeep Prabhu
Publikováno v:
Cell Reports, Vol 42, Iss 7, Pp 112794- (2023)
Summary: Relapse of acute myeloid leukemia (AML) remains a significant concern due to persistent leukemia-initiating stem cells (LICs) that are typically not targeted by most existing therapies. Using a murine AML model, human AML cell lines, and pat
Externí odkaz:
https://doaj.org/article/ce35a814bf814b97aa20a01a202f9e01
Autor:
Baiye Ruan, Robert F. Paulson
Publikováno v:
Frontiers in Physiology, Vol 13 (2023)
Steady state erythropoiesis produces new erythrocytes at a constant rate to replace the senescent cells that are removed by macrophages in the liver and spleen. However, infection and tissue damage disrupt the production of erythrocytes by steady sta
Externí odkaz:
https://doaj.org/article/fbeaf2a05da144b5aab9d427285b6751
Autor:
Yaxian Kong, Bei Jia, Chenchen Zhao, David F. Claxton, Arati Sharma, Charyguly Annageldiyev, Joseph S. Fotos, Hui Zeng, Robert F. Paulson, K. Sandeep Prabhu, Hong Zheng
Publikováno v:
Journal of Hematology & Oncology, Vol 12, Iss 1, Pp 1-11 (2019)
Abstract Background Successful treatment for acute myeloid leukemia (AML) remains challenging. Inhibiting immune checkpoint to enhance anti-tumor response is an attractive strategy for effective leukemia therapeutics. CD73 is a recently recognized im
Externí odkaz:
https://doaj.org/article/0af86c29d57640ac8a9139d616b7bb2e
Publikováno v:
Cells, Vol 9, Iss 3, p 634 (2020)
Bone marrow medullary erythropoiesis is primarily homeostatic. It produces new erythrocytes at a constant rate, which is balanced by the turnover of senescent erythrocytes by macrophages in the spleen. Despite the enormous capacity of the bone marrow
Externí odkaz:
https://doaj.org/article/b8e0230645cd48d0bf219a19dfbe70d7
Autor:
Adwitia Dey, Joselyn N. Allen, James W. Fraser, Lindsay M. Snyder, Yuan Tian, Limin Zhang, Robert F. Paulson, Andrew Patterson, Margherita T. Cantorna, Pamela A. Hankey-Giblin
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Neurodegeneration is a critical problem in aging populations and is characterized by severe central nervous system (CNS) inflammation. Macrophages closely regulate inflammation in the CNS and periphery by taking on different activation states. The so
Externí odkaz:
https://doaj.org/article/ef4e1224294c4953ab00e676ad87afbf
Autor:
Shailaja Hegde, Robert F. Paulson
Publikováno v:
BioTechniques, Vol 36, Iss 6, Pp 936-940 (2004)
Externí odkaz:
https://doaj.org/article/1f8c0cb1b2a24737bef41f84923a147b
Autor:
Nicole M Anderson, Mojib Javadi, Elizabeth Berndl, Zorana Berberovic, Monica L Bailey, Kai Huang, Ann M Flenniken, Lucy R Osborne, S Lee Adamson, Janet Rossant, Christin Carter-Su, Chen Wang, Kelly M McNagny, Robert F Paulson, Mark D Minden, William L Stanford, Dwayne L Barber
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e75472 (2013)
Utilizing ENU mutagenesis, we identified a mutant mouse with elevated platelets. Genetic mapping localized the mutation to an interval on chromosome 19 that encodes the Jak2 tyrosine kinase. We identified a A3056T mutation resulting in a premature st
Externí odkaz:
https://doaj.org/article/0199f61192784ce99fbae49a0da0fce4
Autor:
Dai-Chen Wu, Robert F Paulson
Publikováno v:
PLoS ONE, Vol 5, Iss 6, p e11303 (2010)
Bone marrow erythropoiesis is primarily homeostatic, producing new erythrocytes at a constant rate. However at times of acute anemia, new erythrocytes must be rapidly produced much faster than bone marrow steady state erythropoiesis. At these times s
Externí odkaz:
https://doaj.org/article/833355e339bc43598ba4db03fa58c2da
Publikováno v:
Antioxidants & Redox Signaling; Apr2011, Vol. 14 Issue 8, p1403-1412, 10p
Publikováno v:
Journal of Hematotherapy & Stem Cell Research; Apr2003, Vol. 12 Issue 2, p165-177, 13p