Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Peter Bergsten"'
Autor:
Thomas Pixner, Tatsiana Chaikouskaya, Wanda Lauth, Georg Zimmermann, Katharina Mörwald, Julia Lischka, Dieter Furthner, Elisabeth Awender, Sabine Geiersberger, Katharina Maruszczak, Anders Forslund, Christian-Heinz Anderwald, Janne Cadamuro, Daniel Weghuber, Peter Bergsten
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
BackgroundFasting levels of glucagon are known to be elevated in youth and adults with type 2 diabetes mellitus (T2D). Children and adolescents with obesity were previously reported to show increasing fasting and post-glucose-challenge hyperglucagone
Externí odkaz:
https://doaj.org/article/5791e53625f141b086aef801b27573ac
Autor:
Zhe Jin, Hayma Hammoud, Amol Keshavasa Bhandage, Sergiy Vasylyovych Korol, Olivia Trujeque-Ramos, Stasini Koreli, Zhitao Gong, Azasul Islam Chowdhury, Friederike Andrea Sandbaumhüter, Erik Tomas Jansson, Robin Sean Lindsay, Gustaf Christoffersson, Per Erik Andrén, Per-Ola Carlsson, Peter Bergsten, Masood Kamali-Moghaddam, Bryndis Birnir
Publikováno v:
EBioMedicine, Vol 105, Iss , Pp 105217- (2024)
Summary: Background: γ-aminobutyric acid (GABA), known as the main inhibitory neurotransmitter in the brain, exerts immunomodulatory functions by interaction with immune cells, including T cells. Metabolic programs of T cells are closely linked to t
Externí odkaz:
https://doaj.org/article/fb8964c5e13b45b2a6723e83c99f1a33
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 37, Iss 6, Pp 2520-2528 (2023)
Abstract Background Decreasing hyperinsulinemia is crucial in preventing laminitis in insulin dysregulated (ID) horses. Complementary pharmacological treatments that efficiently decrease postprandial hyperinsulinemia in ID horses are needed. Objectiv
Externí odkaz:
https://doaj.org/article/ec181aa4d11c44c8b3a7c22177c862e5
Autor:
Maria Kopsida, Ada Lerma Clavero, Jaafar Khaled, David Balgoma, Clara Luna-Marco, Azazul Chowdhury, Sofi Sennefelt Nyman, Fredrik Rorsman, Charlotte Ebeling Barbier, Peter Bergsten, Hans Lennernäs, Mikael Hedeland, Femke Heindryckx
Publikováno v:
Molecular Metabolism, Vol 79, Iss , Pp 101846- (2024)
Hepatocellular carcinoma (HCC) is characterized by a low and variable response to chemotherapeutic treatments. One contributing factor to the overall pharmacodynamics is the activation of endoplasmic reticulum (ER) stress pathways. This is a cellular
Externí odkaz:
https://doaj.org/article/a28070bb6a72401c97ac140010fab73d
Autor:
Rasmus Stenlid, Sara Y. Cerenius, Quan Wen, Banu Küçükemre Aydin, Hannes Manell, Azazul Chowdhury, Hjalti Kristinsson, Iris Ciba, Erik S. Gjessing, Katharina Mörwald, Julian Gomahr, Verena Heu, Daniel Weghuber, Anders Forslund, Peter Bergsten
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
BackgroundGLP-1 receptor agonists (GLP-1RA) are increasingly used to treat adolescent obesity. However, the effect on endogenous GLP-1 secretory patterns following treatment in adolescents is unknown. The GLP-1RA exenatide was shown to significantly
Externí odkaz:
https://doaj.org/article/c0fe63dd77744e8b9f14af9a029087ce
Publikováno v:
Upsala Journal of Medical Sciences, Vol 127, Pp 1-8 (2022)
Background: Obesity in adolescents is increasing worldwide and associated with an elevated cardiovascular risk later in life. In a group-comparative study, we investigated the association between adiposity in adolescents and signs of vascular aging a
Externí odkaz:
https://doaj.org/article/2d44fadfcf80479a88c6ff855a0bb7c9
Autor:
Rasmus Stenlid, David Olsson, Jing Cen, Hannes Manell, Charlotte Haglind, Azazul Islam Chowdhury, Peter Bergsten, Anna Nordenström, Maria Halldin
Publikováno v:
Clinical and Translational Science, Vol 15, Iss 1, Pp 182-194 (2022)
Abstract Inborn errors of mitochondrial fatty acid oxidation (FAO), such as medium‐chain acyl‐CoA dehydrogenase deficiency (MCAD) and very long‐chain acyl‐CoA dehydrogenase deficiency (VLCAD) affects cellular function and whole‐body metabol
Externí odkaz:
https://doaj.org/article/db6476faf15045b5b713c69b949a33a7
Metformin Can Attenuate Beta-Cell Hypersecretion—Implications for Treatment of Children with Obesity
Autor:
Quan Wen, Rasmus Stenlid, Azazul Islam Chowdhury, Iris Ciba, Banu Aydin, Sara Y. Cerenius, Hannes Manell, Anders Forslund, Peter Bergsten
Publikováno v:
Metabolites, Vol 13, Iss 8, p 917 (2023)
In children with obesity, insulin hypersecretion is proposed to precede insulin resistance. We investigated if metformin could be used to attenuate insulin secretion from palmitate-treated isolated islets and its implication for children with obesity
Externí odkaz:
https://doaj.org/article/76520127bb024eadad20968b0f2b2ed9
Autor:
Rasmus Stenlid, Hannes Manell, Rikard Seth, Sara Y. Cerenius, Azazul Chowdhury, Camilla Roa Cortés, Isabelle Nyqvist, Thomas Lundqvist, Maria Halldin, Peter Bergsten
Publikováno v:
Metabolites, Vol 13, Iss 7, p 780 (2023)
(1) Background: Deficiencies of mitochondrial fatty acid oxidation (FAO) define a subgroup of inborn errors of metabolism, with medium-chain acyl-CoA dehydrogenase deficiency (MCAD) and very long-chain acyl-CoA dehydrogenase deficiency (VLCAD) being
Externí odkaz:
https://doaj.org/article/cdf4d614c37a4ae19b2cf545f02add49
Autor:
Katharina Maruszczak, Konrad Radzikowski, Sebastian Schütz, Harald Mangge, Peter Bergsten, Anders Forslund, Hannes Manell, Thomas Pixner, Håkan Ahlström, Joel Kullberg, Katharina Mörwald, Daniel Weghuber
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
ObjectiveOver the years, non-alcoholic fatty liver (NAFLD) disease has progressed to become the most frequent chronic liver disease in children and adolescents. The full pathology is not yet known, but disease progression leads to cirrhosis and hepat
Externí odkaz:
https://doaj.org/article/422f72c04dc84603a266efcd7ac1b805