Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Kenneth J. Livak"'
Autor:
Livius Penter, Mehdi Borji, Adi Nagler, Haoxiang Lyu, Wesley S. Lu, Nicoletta Cieri, Katie Maurer, Giacomo Oliveira, Aziz M. Al’Khafaji, Kiran V. Garimella, Shuqiang Li, Donna S. Neuberg, Jerome Ritz, Robert J. Soiffer, Jacqueline S. Garcia, Kenneth J. Livak, Catherine J. Wu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Single-cell transcriptomics has become the definitive method for classifying cell types and states, and can be augmented with genotype information to improve cell lineage identification. Due to constraints of short-read sequencing, current m
Externí odkaz:
https://doaj.org/article/db7bcebda28b4a739047f63c97488177
Autor:
Pavan Bachireddy, Elham Azizi, Cassandra Burdziak, Vinhkhang N. Nguyen, Christina S. Ennis, Katie Maurer, Cameron Y. Park, Zi-Ning Choo, Shuqiang Li, Satyen H. Gohil, Neil G. Ruthen, Zhongqi Ge, Derin B. Keskin, Nicoletta Cieri, Kenneth J. Livak, Haesook T. Kim, Donna S. Neuberg, Robert J. Soiffer, Jerome Ritz, Edwin P. Alyea, Dana Pe’er, Catherine J. Wu
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 113011- (2023)
Externí odkaz:
https://doaj.org/article/c8c0c331d71e45789e2a6e510d78fc48
Autor:
Elisa ten Hacken, Kendell Clement, Shuqiang Li, María Hernández-Sánchez, Robert Redd, Shu Wang, David Ruff, Michaela Gruber, Kaitlyn Baranowski, Jose Jacob, James Flynn, Keith W. Jones, Donna Neuberg, Kenneth J. Livak, Luca Pinello, Catherine J. Wu
Publikováno v:
Genome Biology, Vol 21, Iss 1, Pp 1-11 (2020)
Abstract CRISPR-Cas9 gene editing has transformed our ability to rapidly interrogate the functional impact of somatic mutations in human cancers. Droplet-based technology enables the analysis of Cas9-introduced gene edits in thousands of single cells
Externí odkaz:
https://doaj.org/article/0fc6668360f84aa68cc28a219254ce26
Autor:
Alexandra B. Ysasi, Robert D. Bennett, Willi Wagner, Cristian D. Valenzuela, Andrew B. Servais, Akira Tsuda, Saumyadipta Pyne, Shuqiang Li, Jonna Grimsby, Prapti Pokharel, Kenneth J. Livak, Maximilian Ackermann, Paul C. Blainey, Steven J. Mentzer
Publikováno v:
Frontiers in Medicine, Vol 7 (2020)
Lung regeneration occurs in a variety of adult mammals after surgical removal of one lung (pneumonectomy). Previous studies of murine post-pneumonectomy lung growth have identified regenerative “hotspots” in subpleural alveolar ducts; however, th
Externí odkaz:
https://doaj.org/article/1d3219b82a0046cf97d080489744ae17
Autor:
Jan A. Burger, Dan A. Landau, Amaro Taylor-Weiner, Ivana Bozic, Huidan Zhang, Kristopher Sarosiek, Lili Wang, Chip Stewart, Jean Fan, Julia Hoellenriegel, Mariela Sivina, Adrian M. Dubuc, Cameron Fraser, Yulong Han, Shuqiang Li, Kenneth J. Livak, Lihua Zou, Youzhong Wan, Sergej Konoplev, Carrie Sougnez, Jennifer R. Brown, Lynne V. Abruzzo, Scott L. Carter, Michael J. Keating, Matthew S. Davids, William G. Wierda, Kristian Cibulskis, Thorsten Zenz, Lillian Werner, Paola Dal Cin, Peter Kharchencko, Donna Neuberg, Hagop Kantarjian, Eric Lander, Stacey Gabriel, Susan O’Brien, Anthony Letai, David A. Weitz, Martin A. Nowak, Gad Getz, Catherine J. Wu
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
The BTK inhibitor ibrutinib is used to treat chronic lymphocytic leukaemia, however some patients develop resistance to the drug. Here, the authors use genomic analyses to examine the clonal evolution of 5 patients that develop resistance to ibrutini
Externí odkaz:
https://doaj.org/article/31a1991cd4d64583af26755ec24a7d52
Autor:
Naveen Ramalingam, Brian Fowler, Lukasz Szpankowski, Anne Leyrat, Kyle Hukari, Myo Thu, Wiganda Yorza, Michael Norris, Chris Cesar, Joe Shuga, Michael Gonzales, Chad D Sanada, David Wang, Rudy Yeung, Win Hwang, Justin Axsom, Naga Sai Gopi Krishna Devaraju, Ninez DeLos Angeles, Cassandra Greene, Ming-Fang Zhou, Eng-Seng Ong, Chang-Chee Poh, Marcos Lam, Henry Choi, Zaw HToo, Leo Lee, Chee-Sing Chin, Zhong-Wei Shen, Tracy Lu, Ilona Holcomb, Aik Ooi, Craig Stolarczyk, Tony Shuga, Kenneth J Livak, Marc Unger, Jay West
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 4 (2016)
The study of single cells has evolved over the past several years to include expression and genomic analysis of an increasing number of single cells. Several studies have demonstrated wide-spread variation and heterogeneity within cell populations of
Externí odkaz:
https://doaj.org/article/19dd821ea2d84244b5cf1248afdb54db