Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Anna Esteve"'
Autor:
Sara Cabrero-de las Heras, Xavier Hernández-Yagüe, Andrea González, Ferran Losa, Gemma Soler, Cristina Bugés, Iosune Baraibar, Anna Esteve, Miguel Ángel Pardo-Cea, Anne Hansen Ree, Neus Martínez-Bosch, Maria Nieva, Eva Musulén, Sebastian Meltzer, Tania Lobato, Carla Vendrell-Ayats, Cristina Queralt, Pilar Navarro, Clara Montagut, Ferran Grau-Leal, David Camacho, Raquel Legido, Núria Mulet-Margalef, Eva Martínez-Balibrea
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 176, Iss , Pp 116857- (2024)
Metastatic colorectal cancer (mCRC) currently lacks reliable biomarkers for precision medicine, particularly for chemotherapy-based treatments. This study examines the behavior of 11 CXC chemokines in the blood of 104 mCRC patients undergoing first-l
Externí odkaz:
https://doaj.org/article/9a44f4acd0ee417b9239aafcd72443e1
Autor:
Miguel Angel Pardo-Cea, Xavier Farré, Anna Esteve, Joanna Palade, Roderic Espín, Francesca Mateo, Eric Alsop, Marc Alorda, Natalia Blay, Alexandra Baiges, Arzoo Shabbir, Francesc Comellas, Antonio Gómez, Montserrat Arnan, Alex Teulé, Monica Salinas, Laura Berrocal, Joan Brunet, Paula Rofes, Conxi Lázaro, Miquel Conesa, Juan Jose Rojas, Lars Velten, Wojciech Fendler, Urszula Smyczynska, Dipanjan Chowdhury, Yong Zeng, Housheng Hansen He, Rong Li, Kendall Van Keuren-Jensen, Rafael de Cid, Miquel Angel Pujana
Publikováno v:
Genome Medicine, Vol 16, Iss 1, Pp 1-22 (2024)
Abstract Background The immune system has a central role in preventing carcinogenesis. Alteration of systemic immune cell levels may increase cancer risk. However, the extent to which common genetic variation influences blood traits and cancer risk r
Externí odkaz:
https://doaj.org/article/5f8c5c339bf345519940b8098cf83a6d
Autor:
Cinthia Aguilera, Anna Esteve-Garcia, Carlos Casasnovas, Valentina Vélez-Santamaria, Laura Rausell, Pablo Gargallo, Javier Garcia-Planells, Pedro Alía, Núria Llecha, Ariadna Padró-Miquel
Publikováno v:
BMC Medical Genomics, Vol 16, Iss 1, Pp 1-6 (2023)
Abstract Background Friedreich ataxia is the most common inherited ataxia in Europe and is mainly caused by biallelic pathogenic expansions of the GAA trinucleotide repeat in intron 1 of the FXN gene that lead to a decrease in frataxin protein levels
Externí odkaz:
https://doaj.org/article/74f76043e3574e97921cb373b5339ff2
Autor:
Valentina Casella, Eva Domenjo-Vila, Anna Esteve-Codina, Mireia Pedragosa, Paula Cebollada Rica, Enric Vidal, Ivan de la Rubia, Cristina López-Rodríguez, Gennady Bocharov, Jordi Argilaguet, Andreas Meyerhans
Publikováno v:
Cell Death and Disease, Vol 14, Iss 12, Pp 1-13 (2023)
Abstract Acute infection and chronic infection are the two most common fates of pathogenic virus infections. While several factors that contribute to these fates are described, the critical control points and the mechanisms that underlie infection fa
Externí odkaz:
https://doaj.org/article/dd0fc59a75174ebaada2f5ec64e26ee9
Autor:
M. C. Martinez-Campanario, Marlies Cortés, Alazne Moreno-Lanceta, Lu Han, Chiara Ninfali, Verónica Domínguez, María J. Andrés-Manzano, Marta Farràs, Anna Esteve-Codina, Carlos Enrich, Francisco J. Díaz-Crespo, Belén Pintado, Joan C. Escolà-Gil, Pablo García de Frutos, Vicente Andrés, Pedro Melgar-Lesmes, Antonio Postigo
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Abstract Accumulation of lipid-laden macrophages within the arterial neointima is a critical step in atherosclerotic plaque formation. Here, we show that reduced levels of the cellular plasticity factor ZEB1 in macrophages increase atherosclerotic pl
Externí odkaz:
https://doaj.org/article/4d6ce7e1890e4d409029a5183b07f6a2
Autor:
Marlies Cortés, Agnese Brischetto, M. C. Martinez-Campanario, Chiara Ninfali, Verónica Domínguez, Sara Fernández, Raquel Celis, Anna Esteve-Codina, Juan J. Lozano, Julia Sidorova, Gloria Garrabou, Anna-Maria Siegert, Carlos Enrich, Belén Pintado, Manuel Morales-Ruiz, Pedro Castro, Juan D. Cañete, Antonio Postigo
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Acute inflammation can either resolve through immunosuppression or persist, leading to chronic inflammation. These transitions are driven by distinct molecular and metabolic reprogramming of immune cells. The anti-diabetic drug Metformin inh
Externí odkaz:
https://doaj.org/article/655d9568306f4699a3a035f4045e67b7
Autor:
Alba Segarra-Casas, Vicente A. Yépez, German Demidov, Steven Laurie, Anna Esteve-Codina, Julien Gagneur, Yolande Parkhurst, Robert Muni-Lofra, Elizabeth Harris, Chiara Marini-Bettolo, Volker Straub, Ana Töpf
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 14, p 7793 (2024)
Duchenne and Becker muscular dystrophies, caused by pathogenic variants in DMD, are the most common inherited neuromuscular conditions in childhood. These diseases follow an X-linked recessive inheritance pattern, and mainly males are affected. The m
Externí odkaz:
https://doaj.org/article/5736024c173641538498d2098703d4b5
Autor:
Anna Esteve-Garcia, Estefania Cobos, Cristina Sau, Ariadna Padró-Miquel, Jaume Català-Mora, Pilar Barberán-Martínez, José M. Millán, Gema García-García, Cinthia Aguilera
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Introduction:TULP1 exemplifies the remarkable clinical and genetic heterogeneity observed in inherited retinal dystrophies. Our research describes the clinical and molecular characteristics of a patient manifesting an atypical retinal dystrophy patte
Externí odkaz:
https://doaj.org/article/7498f0855a6149f8b650b1741e4a7da2
Publikováno v:
Pharmacology Research & Perspectives, Vol 12, Iss 1, Pp n/a-n/a (2024)
Abstract Off‐label use (OLU) is quite common in oncology due to the complexity of cancer and the time‐consuming regulatory process. However, outcomes of OLU in cancer treatment remain unclear. This study aimed to evaluate the overall survival (OS
Externí odkaz:
https://doaj.org/article/e641a54fb2d442639d55294939dbeaa6
Autor:
Sandra Fontanals, Anna Esteve, Andrea González, Cristina Ibáñez, Javier Martínez, Ricard Mesía, Ana Clopés
Publikováno v:
Cancer Medicine, Vol 12, Iss 16, Pp 17112-17125 (2023)
Abstract Purpose Medicines in special situations (MSS) refer to off‐label or to unlicensed drugs under investigation (compassionate use). Our objectives were to evaluate characteristics and to estimate overall survival (OS), event‐free survival (
Externí odkaz:
https://doaj.org/article/e109919815c54fed8ef7e66d141585d2