Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Wei-Yi Ong"'
Autor:
Damien Meng-Kiat Leow, Irwin Kee-Mun Cheah, Lucrecia Chen, Yang-Kai Ng, Crystal Jing-Jing Yeo, Barry Halliwell, Wei-Yi Ong
Publikováno v:
Antioxidants, Vol 13, Iss 6, p 693 (2024)
Cell death involving oxidative stress and mitochondrial dysfunction is a major cause of dopaminergic neuronal loss in the substantia nigra (SN) of Parkinson’s disease patients. Ergothioneine (ET), a natural dietary compound, has been shown to have
Externí odkaz:
https://doaj.org/article/4e01849889b64fed887664b880bec3b1
Autor:
Akhlaq A. Farooqui, Tahira Farooqui, Grace Y. Sun, Teng-Nan Lin, Daniel B. L. Teh, Wei-Yi Ong
Publikováno v:
Biomedicines, Vol 11, Iss 4, p 1181 (2023)
Although there is increasing evidence that oxidative stress and inflammation induced by COVID-19 may contribute to increased risk and severity of thromboses, the underlying mechanism(s) remain to be understood. The purpose of this review is to highli
Externí odkaz:
https://doaj.org/article/fbb35a6c3e884abe856a14b559857406
Autor:
Damien Meng-Kiat Leow, Irwin Kee-Mun Cheah, Zachary Wei-Jie Fong, Barry Halliwell, Wei-Yi Ong
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 6, p 5498 (2023)
Recent findings have suggested that the natural compound ergothioneine (ET), which is synthesised by certain fungi and bacteria, has considerable cytoprotective potential. We previously demonstrated the anti-inflammatory effects of ET on 7-ketocholes
Externí odkaz:
https://doaj.org/article/58c85e421bd6436c86cefb738f4f0cdb
Publikováno v:
Molecules, Vol 27, Iss 11, p 3607 (2022)
Recent studies on the ethnomedicinal use of Clinacanthus nutans suggest promising anti-inflammatory, anti-tumorigenic, and antiviral properties for this plant. Extraction of the leaves with polar and nonpolar solvents has yielded many C-glycosyl flav
Externí odkaz:
https://doaj.org/article/0c5a8938594d4d1ab5c068444e9780dc
Autor:
Sandra Soh, Wei-Yi Ong
Publikováno v:
Cells, Vol 11, Iss 3, p 457 (2022)
Withanolide A is a naturally occurring phytochemical that is found in Ashwagandha (Withania somnifera, fam. Solanaceae) or Indian Ginseng. In the current study, we elucidated the effect of withanolide A on 7-ketocholesterol (7KC) induced injury in hC
Externí odkaz:
https://doaj.org/article/d1a0f159e9ad416591dba1b7a4ccc25e
Autor:
Zheng-Yi Li, Yoon Hee Chung, Eun-Joo Shin, Duy-Khanh Dang, Ji Hoon Jeong, Sung Kwon Ko, Seung-Yeol Nah, Tae Gon Baik, Jin Hyeong Jhoo, Wei-Yi Ong, Toshitaka Nabeshima, Hyoung-Chun Kim
Publikováno v:
Journal of Neuroinflammation, Vol 14, Iss 1, Pp 1-22 (2017)
Abstract Background Ginkgo biloba has been reported to possess free radical-scavenging antioxidant activity and anti-inflammatory properties. In our pilot study, YY-1224, a terpene trilactone-strengthened extract of G. biloba, showed anti-inflammator
Externí odkaz:
https://doaj.org/article/6867afb289db48a4b826cd2bd941df8e
Autor:
Aaron Tan, Maria V. Babak, Gopalakrishnan Venkatesan, Clarissa Lim, Karl-Norbert Klotz, Deron Raymond Herr, Siew Lee Cheong, Stephanie Federico, Giampiero Spalluto, Wei-Yi Ong, Yu Zong Chen, Jason Siau Ee Loo, Giorgia Pastorin
Publikováno v:
Molecules, Vol 24, Iss 20, p 3661 (2019)
Human A3 adenosine receptor hA3AR has been implicated in gastrointestinal cancer, where its cellular expression has been found increased, thus suggesting its potential as a molecular target for novel anticancer compounds. Observation made in our prev
Externí odkaz:
https://doaj.org/article/21a6812bfdcc407e937785beaa8ff631
Autor:
Wei-Yi Ong, John Jia En Chua
Publikováno v:
Neural Regeneration Research, Vol 14, Iss 12, Pp 2071-2072 (2019)
Externí odkaz:
https://doaj.org/article/36235a3952a442328225ec5d900f1c8a
Autor:
Wei-Yi Ong, Mary Pei-Ern Ng, Sau-Yeen Loke, Shalai Jin, Ya-Jun Wu, Kazuhiro Tanaka, Peter Tsun-Hon Wong
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68335 (2013)
Atherosclerotic stenosis of cerebral arteries or intracranial large artery disease (ICLAD) is a major cause of stroke especially in Asians, Hispanics and Africans, but relatively little is known about gene expression changes in vessels at risk. This
Externí odkaz:
https://doaj.org/article/01f34b9dfa924a308e1c09a49803ad88
Autor:
Jasmine Hui Min Lee, Tatsuma Hind, Jerold Chun, Siew Mon Lim, Nicholas Wei Jie Hay, Wei-Yi Ong, Malavika Srikanth, Deron R. Herr, Wee Siong Chew, Rich Rivera
Publikováno v:
European Journal of Pharmacology. 841:49-56
Lysophosphatidic acid receptor 1 (LPA1) is one of six G protein-coupled receptors (GPCRs) activated by the bioactive lipid, lysophosphatidic acid (LPA). Previous studies have shown that LPA1 signaling plays a major role in the pathophysiology of neur