Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Toshiyuki Takehara"'
Autor:
Kensuke Toriumi, Yuta Onodera, Toshiyuki Takehara, Tatsufumi Mori, Joe Hasei, Kanae Shigi, Natsumi Iwawaki, Toshifumi Ozaki, Masao Akagi, Mahito Nakanishi, Takeshi Teramura
Publikováno v:
iScience, Vol 26, Iss 7, Pp 106946- (2023)
Summary: Mesenchymal stem cells (MSCs) are used as a major source for cell therapy, and its application is expanding in various diseases. On the other hand, reliable method to evaluate quality and therapeutic properties of MSC is limited. In this stu
Externí odkaz:
https://doaj.org/article/af0091356a444936a1dae3d65fd52613
Autor:
Yuta Onodera, Takeshi Teramura, Toshiyuki Takehara, Maki Itokazu, Tatsufumi Mori, Kanji Fukuda
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0204860 (2018)
Tissue renewal and muscle regeneration largely rely on the proliferation and differentiation of muscle stem cells called muscular satellite cells (MuSCs). MuSCs are normally quiescent, but they are activated in response to various stimuli, such as in
Externí odkaz:
https://doaj.org/article/b3ca824476254fe6b764acd5e556312a
Publikováno v:
FEBS Open Bio, Vol 5, Iss 1, Pp 492-501 (2015)
Oxidative stress within the arthritis joint has been indicated to be involved in generating mediators for tissue degeneration and inflammation. COX‐2 is a mediator in inflammatory action, pain and some catabolic reactions in inflamed tissues. Here,
Externí odkaz:
https://doaj.org/article/30849c63087f4e53b94bc872c704381b
Publikováno v:
FEBS Open Bio, Vol 5, Iss 1, Pp 476-484 (2015)
One important pharmacological function of hyaluronic acid (HA) in chondrocytes is reduction of cellular superoxide generation and accumulation. Here we demonstrated a relationship between HA supplementation and accumulation of Nuclear factor‐erythr
Externí odkaz:
https://doaj.org/article/6481c50207494948b790650f2534062e
Autor:
Tatsufumi Mori, Masatsugu Igarashi, Yuta Onodera, Toshiyuki Takehara, Maki Itokazu, Takeshi Teramura
Publikováno v:
Biochemical and Biophysical Research Communications. 651:70-78
Autor:
Kanae Shigi, Kanji Fukuda, Toshiyuki Takehara, Shinichi Nakao, Yuta Onodera, Takatoshi Tsujimoto, Takeshi Teramura, Kei Houri, Tatsufumi Mori
Publikováno v:
Biochemical and Biophysical Research Communications. 523:707-712
Removal of dysfunctional mitochondria is essential step to maintain normal cell physiology, and selective autophagy in mitochondria, called mitophagy, plays a critical role in quality control of mitochondria. While in several diseases and aging, dist
Autor:
Tatsufumi Mori, Yuta Onodera, Maki Itokazu, Toshiyuki Takehara, Kanae Shigi, Natsumi Iwawaki, Masao Akagi, Takeshi Teramura
Publikováno v:
Mechanisms of ageing and development. 201
Frailty of the locomotory organs has become a widespread problem in the geriatric population. The major factor leading to frailty is an age-associated decrease in muscular mass and a reduced number of muscular cells and myofibers. In aged muscular ti
Autor:
Tatsufumi Mori, Toshiyuki Takehara, Kanji Fukuda, Yuta Onodera, Takeshi Teramura, Kayoko Obora
Publikováno v:
Aging Cell
Summary Inflammation-induced reactive oxygen species (ROS) are implicated in cellular dysfunction and an important trigger for aging- or disease-related tissue degeneration. Inflammation-induced ROS in stem cells lead to deterioration of their proper
Autor:
Hirofumi Suemori, Toshiyuki Takehara, Koichi Suzuki, Koichi Matsuda, Kenji Shinohara, Tatsufumi Mori, Yuji Miyashita, Yasumichi Mieno, Kanji Fukuda, Takeshi Teramura
Publikováno v:
Biochemical and biophysical research communications. 503(4)
Purification of undifferentiated cells by removing differentiated parts is an essential step in pluripotent stem cell culture. This process has been traditionally performed manually using a fine glass capillary or plastic tip under a microscope, or b
Autor:
Maki Itokazu, Toshiyuki Takehara, Tatsufumi Mori, Takeshi Teramura, Yuta Onodera, Kanji Fukuda
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0204860 (2018)
PLoS ONE
PLoS ONE
Tissue renewal and muscle regeneration largely rely on the proliferation and differentiation of muscle stem cells called muscular satellite cells (MuSCs). MuSCs are normally quiescent, but they are activated in response to various stimuli, such as in