Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Thomas Lehner"'
Autor:
Yufei Wang, Trevor Whittall, Stuart Neil, Gary Britton, Mukesh Mistry, Supachai Rerks-Ngarm, Punnee Pitisuttithum, Jaranit Kaewkungwal, Sorachai Nitayaphan, Xuesong Yu, Alicia Sato, Robert J. O’Connell, Nelson L. Michael, Merlin L. Robb, Jerome H. Kim, Thomas Lehner
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract HIV infection affects 37 million people and about 1.7 million are infected annually. Among the phase III clinical trials only the RV144 vaccine trial elicited significant protection against HIV-1 acquisition, but the efficacy and immune memo
Externí odkaz:
https://doaj.org/article/fe03733a163a4761833618d8fb3d76d0
Autor:
Qing Yang, Fengling Feng, Pingchao Li, Enxiang Pan, Chunxiu Wu, Yizi He, Fan Zhang, Jin Zhao, Ruiting Li, Liqiang Feng, Fengyu Hu, Linghua Li, Huachun Zou, Weiping Cai, Thomas Lehner, Caijun Sun, Ling Chen
Publikováno v:
Advanced Science, Vol 6, Iss 13, Pp n/a-n/a (2019)
Abstract The latent viral reservoir is the source of viral rebound after interruption of antiretroviral therapy (ART) and is the major obstacle in eradicating the latent human immunodeficiency virus‐1 (HIV‐1). In this study, arsenic class of mine
Externí odkaz:
https://doaj.org/article/b884d10eedfd4e2a9eb2ad8286d392e6
Autor:
Kimberly A Walters, Yungui Huang, Marco Azaro, Kathleen Tobin, Thomas Lehner, Linda M Brzustowicz, Veronica J Vieland
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e84696 (2014)
Human geneticists are increasingly turning to study designs based on very large sample sizes to overcome difficulties in studying complex disorders. This in turn almost always requires multi-site data collection and processing of data through central
Externí odkaz:
https://doaj.org/article/dc2b954ca51b441591b375ee63ac776e
Autor:
Yufei Wang, Trevor Whittall, Durdana Rahman, Evelien M Bunnik, Robert Vaughan, Jørgen Schøller, Lesley A Bergmeier, David Montefiori, Mahavir Singh, Hanneke Schuitemaker, Thomas Lehner
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e34433 (2012)
The AID/APOBEC family (activation induced deaminase/apolipoprotein B mRNA editing cytokine deaminase) in B cells play important roles in adaptive and innate immunity. Whereas APOBEC3G has been studied in CD4+ T cells and myeloid cells its functional
Externí odkaz:
https://doaj.org/article/ed06f658a4d04b789928d0a168119e7b
Autor:
Cherry Kingsley, Barry Peters, Kaboutar Babaahmady, Laura Pomeroy, Durdana Rahman, Robert Vaughan, Thomas Lehner
Publikováno v:
PLoS ONE, Vol 4, Iss 11, p e7938 (2009)
BACKGROUND:Epidemiological studies suggest that allogeneic immunity may inhibit HIV-1 transmission from mother to baby and is less frequent in multiparous than uniparous women. Alloimmune responses may also be elicited during unprotected heterosexual
Externí odkaz:
https://doaj.org/article/c52c745cbe234ccc9ad50fdb7a5e0d21
Autor:
Susan E. Koester, Susan Borja, Linda S. Brady, Tara Dutka, Thomas Lehner, Kathleen R. Merikangas, Anjené M. Addington, P. Alexander Arguello, Miri Gitik, Geetha Senthil, David M. Panchision, Francis J. McMahon, Douglas L. Meinecke
Publikováno v:
Molecular Psychiatry. 24:1576-1582
The Genomics Workgroup of the National Advisory Mental Health Council (NAMHC) recently issued a set of recommendations for advancing the NIMH psychiatric genetics research program and prioritizing subsequent follow-up studies. The report emphasized t
Autor:
Barbara Siegmund, Thomas Lehner
Publikováno v:
Food chemistry. 320
The postharvest ripening behaviour of mangoes (Mangifera indica L.) and particularly the development of colour, volatiles, sensory properties and texture, were investigated. Mangoes cv. Kent from Peru were arranged in a postharvest ripening chamber i
Publikováno v:
Local Government Studies. 44:465-491
In this paper, we evaluate the effect of municipal amalgamations on election turnout in local elections. Following recent studies, we argue that municipal mergers can lead to less information about...
Autor:
Robert E. Handsaker, Donna M. Werling, A. Jeremy Willsey, Chiara Sabatti, Kevin Eggan, Raquel E. Gur, Anjené M. Addington, P. Alexander Arguello, Aarno Palotie, John Blangero, Matthew W. State, Mark J. Daly, Joon Yong An, Nelson B. Freimer, Roel A. Ophoff, Daniel H. Geschwind, Michael Boehnke, David C. Glahn, Steven E. Hyman, Benjamin M. Neale, Thomas Lehner, Hailiang Huang, Carlos N. Pato, David Goldstein, Stephen Sanders, Shan Dong, Gonçalo R. Abecasis, Steven A. McCarroll
Publikováno v:
Nat Neurosci
As technology advances, whole genome sequencing (WGS) is likely to supersede other genotyping technologies. The rate of this change depends on its relative cost and utility. Variants identified uniquely through WGS may reveal novel biological pathway
Publikováno v:
Molecular Psychiatry. 22:1659-1663
The National Institute of Mental Health (NIMH) has made sustained investments in the development of genomic resources over the last two decades. These investments have led to the development of the largest biorepository for psychiatric genetics as a