Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Tadashi Komatsubara"'
Autor:
Chetan Kumawat, Toshiyuki Takahashi, Isao Date, Yousuke Tomita, Masato Tanaka, Shinya Arataki, Tadashi Komatsubara, Angel O. P. Flores, Dongwoo Yu, Mukul Jain
Publikováno v:
Cancers, Vol 16, Iss 13, p 2360 (2024)
Spinal cord tumors, though rare, present formidable challenges in clinical management due to their intricate nature. Traditional treatment modalities like surgery, radiation therapy, and chemotherapy have been the mainstay for managing these tumors.
Externí odkaz:
https://doaj.org/article/cde7fbe9286c4a15a2ffef2b232bd4bc
Autor:
Koji Uotani, Hiroshi Tazawa, Joe Hasei, Tomohiro Fujiwara, Aki Yoshida, Yasuaki Yamakawa, Toshinori Omori, Kazuhisa Sugiu, Tadashi Komatsubara, Hiroya Kondo, Takuya Morita, Masahiro Kiyono, Suguru Yokoo, Toshiaki Hata, Toshiyuki Kunisada, Ken Takeda, Yasuo Urata, Toshiyoshi Fujiwara, Toshifumi Ozaki
Publikováno v:
PLoS ONE, Vol 19, Iss 2, p e0298292 (2024)
Bone and soft-tissue sarcomas are rare malignancies with histological diversity and tumor heterogeneity, leading to the lack of a common molecular target. Telomerase is a key enzyme for keeping the telomere length and human telomerase reverse transcr
Externí odkaz:
https://doaj.org/article/58fc91a9ec63459b8c0966eb8e2ea242
Autor:
Sharvari Gunjotikar, Malcolm Pestonji, Masato Tanaka, Tadashi Komatsubara, Shashank J. Ekade, Ahmed Majid Heydar, Huynh Kim Hieu
Publikováno v:
Journal of Clinical Medicine, Vol 13, Iss 11, p 3208 (2024)
Background: The aging of the population in developing and developed countries has led to a significant increase in the health burden of spinal diseases. These elderly patients often have a number of medical comorbidities due to aging. The need for mi
Externí odkaz:
https://doaj.org/article/8982f2d9ed6c46a88fd99180c0f967ab
Autor:
Tomoyoshi Sakaguchi, Sharvari Gunjotikar, Masato Tanaka, Tadashi Komatsubara, Kajetan Latka, Shashank J. Ekade, Shrinivas P. Prabhu, Kazuhiko Takamatsu, Yosuke Yasuda, Masami Nakagawa
Publikováno v:
Journal of Clinical Medicine, Vol 13, Iss 10, p 2915 (2024)
Purpose: With an increase in the proportion of elderly patients, the global burden of spinal disease is on the rise. This is gradually expected to increase the number of surgical procedures all over the world in the near future. As we know, rehabilit
Externí odkaz:
https://doaj.org/article/768991cf855a44ffa70961240e9082cc
Autor:
Masato Tanaka, Abd El Kader Al Askar, Chetan Kumawat, Shinya Arataki, Tadashi Komatsubara, Takuya Taoka, Koji Uotani, Yoshiaki Oda
Publikováno v:
Medicina, Vol 60, Iss 4, p 616 (2024)
Objectives and Background: To present a novel technique of treatment for a patient with basilar invagination. Basilar invagination (BI) is a congenital condition that can compress the cervicomedullary junction, leading to neurological deficits. Sever
Externí odkaz:
https://doaj.org/article/4abc82843e10485fb6e23fbca2013f2c
Autor:
Akiyoshi Miyamoto, Umesh Parihar, Chetan Kumawat, Abd El Kader Al Askar, Masato Tanaka, Sharvari Gunjotikar, Takuya Taoka, Tadashi Komatsubara, Yoshihiro Fujiwara, Koji Uotani, Shinya Arataki
Publikováno v:
Medicina, Vol 60, Iss 4, p 519 (2024)
Objectives: To investigate the outcomes of early balloon kyphoplasty (BKP) intervention compared with late intervention for osteoporotic vertebral fracture (OVF). Background: Osteoporotic vertebral fracture can lead to kyphotic deformity, severe back
Externí odkaz:
https://doaj.org/article/c066c72dc294405aacf04e45298cefbe
Autor:
Toshinori Omori, Hiroshi Tazawa, Yasuaki Yamakawa, Shuhei Osaki, Joe Hasei, Kazuhisa Sugiu, Tadashi Komatsubara, Tomohiro Fujiwara, Aki Yoshida, Toshiyuki Kunisada, Yasuo Urata, Shunsuke Kagawa, Toshifumi Ozaki, Toshiyoshi Fujiwara
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0250643 (2021)
Soft tissue sarcoma (STS) is a rare cancer that develops from soft tissues in any part of the body. Despite major advances in the treatment of STS, patients are often refractory to conventional radiotherapy, leading to poor prognosis. Enhancement of
Externí odkaz:
https://doaj.org/article/aa5ad1fb44474459ae6369bdf391f6a2
Autor:
Yasuaki Yamakawa, Toshiyoshi Fujiwara, Hiroshi Tazawa, Shuhei Osaki, Toshinori Omori, Shunsuke Kagawa, Tomohiro Fujiwara, Toshiyuki Kunisada, Joe Hasei, Toshifumi Ozaki, Tadashi Komatsubara, Aki Yoshida, Yasuo Urata, Kazuhisa Sugiu
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 4, p e0250643 (2021)
PLoS ONE, Vol 16, Iss 4, p e0250643 (2021)
Soft tissue sarcoma (STS) is a rare cancer that develops from soft tissues in any part of the body. Despite major advances in the treatment of STS, patients are often refractory to conventional radiotherapy, leading to poor prognosis. Enhancement of
Autor:
Yasuaki Yamakawa, Toshiyuki Kunisada, Shunsuke Kagawa, Yusuke Mochizuki, Joe Hasei, Toshifumi Ozaki, Toshinori Omori, Aki Yoshida, Shuhei Osaki, Kazuhisa Sugiu, Tomohiro Fujiwara, Koji Ueda, Hiroya Kondo, Toshiyoshi Fujiwara, Hiroshi Tazawa, Yasuo Urata, Tadashi Komatsubara
Publikováno v:
Cancer chemotherapy and pharmacology. 88(3)
Background Osteosarcoma (OS) is a malignant bone tumor primarily affecting children and adolescents. The prognosis of chemotherapy-refractory OS patients is poor. We developed a tumor suppressor p53–expressing oncolytic adenovirus (OBP-702) that ex
Autor:
Yusuke Mochizuki, Joe Hasei, Toshifumi Ozaki, Hiroshi Tazawa, Miho Kure, Toshiyoshi Fujiwara, Hiroya Kondo, Toshiyuki Kunisada, Aki Yoshida, Shunsuke Kagawa, Kazuhisa Sugiu, Tadashi Komatsubara, Yasuo Urata, Koji Demiya
Publikováno v:
Cancer immunology, immunotherapy : CII. 70(5)
Immune checkpoint inhibitors including anti-programmed cell death 1 (PD-1) antibody have recently improved clinical outcome in certain cancer patients; however, osteosarcoma (OS) patients are refractory to PD-1 blockade. Oncolytic virotherapy has eme