Zobrazeno 1 - 10
of 662
pro vyhledávání: '"Richard E Champlin"'
Autor:
Ajay Sheshadri, Sukh Makhnoon, Amin M Alousi, Lara Bashoura, Rene Andrade, Christopher J Miller, Karen R Stolar, Muhammad Hasan Arain, Laila Noor, Amulya Balagani, Akash Jain, David Blanco, Abel Ortiz, Michael S Taylor, Alex Stenzler, Rohtesh Mehta, Uday R Popat, Chitra Hosing, David E Ost, Richard E Champlin, Burton F Dickey, Susan K Peterson
Publikováno v:
JMIR Formative Research, Vol 6, Iss 2, p e29393 (2022)
BackgroundHome-based spirometry (HS) allows for the early detection of lung complications in recipients of an allogeneic hematopoietic cell transplant (AHCT). Although the usability and acceptability of HS are critical for adherence, patient-reported
Externí odkaz:
https://doaj.org/article/9c6ab0ad97b941c1823c6e7c6b8e6127
Autor:
Radhika Thokala, Simon Olivares, Tiejuan Mi, Sourindra Maiti, Drew Deniger, Helen Huls, Hiroki Torikai, Harjeet Singh, Richard E Champlin, Tamara Laskowski, George McNamara, Laurence J N Cooper
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0159477 (2016)
Adoptive immunotherapy infusing T cells with engineered specificity for CD19 expressed on B- cell malignancies is generating enthusiasm to extend this approach to other hematological malignancies, such as acute myelogenous leukemia (AML). CD123, or i
Externí odkaz:
https://doaj.org/article/6a199d18b6234618b7b0ad5ae27e1c1f
Autor:
Drew C Deniger, Jianqiang Yu, M Helen Huls, Matthew J Figliola, Tiejuan Mi, Sourindra N Maiti, George F Widhopf, Lenka V Hurton, Radhika Thokala, Harjeet Singh, Simon Olivares, Richard E Champlin, William G Wierda, Thomas J Kipps, Laurence J N Cooper
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0128151 (2015)
T cells modified with chimeric antigen receptors (CARs) targeting CD19 demonstrated clinical activity against some B-cell malignancies. However, this is often accompanied by a loss of normal CD19+ B cells and humoral immunity. Receptor tyrosine kinas
Externí odkaz:
https://doaj.org/article/0b6221ad461a4b57be966fe10055051f
Autor:
Nina Shah, Beatriz Martin-Antonio, Hong Yang, Stephanie Ku, Dean A Lee, Laurence J N Cooper, William K Decker, Sufang Li, Simon N Robinson, Takuya Sekine, Simrit Parmar, John Gribben, Michael Wang, Katy Rezvani, Eric Yvon, Amer Najjar, Jared Burks, Indreshpal Kaur, Richard E Champlin, Catherine M Bollard, Elizabeth J Shpall
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76781 (2013)
Natural killer (NK) cells are important mediators of anti-tumor immunity and are active against several hematologic malignancies, including multiple myeloma (MM). Umbilical cord blood (CB) is a promising source of allogeneic NK cells but large scale
Externí odkaz:
https://doaj.org/article/c37a7d4c76584050ad3e3bcf2660a4c7
Autor:
Harjeet Singh, Matthew J Figliola, Margaret J Dawson, Simon Olivares, Ling Zhang, Ge Yang, Sourindra Maiti, Pallavi Manuri, Vladimir Senyukov, Bipulendu Jena, Partow Kebriaei, Richard E Champlin, Helen Huls, Laurence J N Cooper
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64138 (2013)
Adoptive transfer of T cells expressing a CD19-specific chimeric antigen receptor (CAR) is being evaluated in multiple clinical trials. Our current approach to adoptive immunotherapy is based on a second generation CAR (designated CD19RCD28) that sig
Externí odkaz:
https://doaj.org/article/9e74176212bd40a58bea38aeed27eae3
Autor:
Bipulendu Jena, Sourindra Maiti, Helen Huls, Harjeet Singh, Dean A Lee, Richard E Champlin, Laurence J N Cooper
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e57838 (2013)
Clinical trials targeting CD19 on B-cell malignancies are underway with encouraging anti-tumor responses. Most infuse T cells genetically modified to express a chimeric antigen receptor (CAR) with specificity derived from the scFv region of a CD19-sp
Externí odkaz:
https://doaj.org/article/88ac35af49654cb9ab652e8bcc808407
Autor:
Cecele J Denman, Vladimir V Senyukov, Srinivas S Somanchi, Prasad V Phatarpekar, Lisa M Kopp, Jennifer L Johnson, Harjeet Singh, Lenka Hurton, Sourindra N Maiti, M Helen Huls, Richard E Champlin, Laurence J N Cooper, Dean A Lee
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e30264 (2012)
NK cells have therapeutic potential for a wide variety of human malignancies. However, because NK cells expand poorly in vitro, have limited life spans in vivo, and represent a small fraction of peripheral white blood cells, obtaining sufficient cell
Externí odkaz:
https://doaj.org/article/d590fb68bb70428792b653a2df2c3c92
Autor:
Leandro de Padua Silva, Poliana A. Patah, Rima M. Saliba, Nicholas A. Szewczyk, Lisa Gilman, Joyce Neumann, Xiang-Yang Han, Jeffrey Tarrand, Rachel Ribeiro, Alison Gulbis, Elizabeth J. Shpall, Roy Jones, Uday Popat, Julia A. Walker, Demetrios Petropoulos, Alexandre Chiattone, John Stewart, Maha El-Zimaity, Paolo Anderlini, Sergio Giralt, Richard E Champlin, Marcos de Lima
Publikováno v:
Haematologica, Vol 95, Iss 7 (2010)
Background Hemorrhagic cystitis is a common cause of morbidity after allogeneic stem cell transplantation, frequently associated with BK virus infection. We hypothesized that patients with positive BK viruria before unrelated or mismatched related do
Externí odkaz:
https://doaj.org/article/ef195ac0543c4636ba06554fd9ecf1a0
Autor:
Curtis Marcoux, David Marin, Jeremy Ramdial, Gheath AlAtrash, Amin M. Alousi, Betul Oran, Partow Kebriaei, Uday R. Popat, Katayoun Rezvani, Richard E. Champlin, Elizabeth J. Shpall, Rohtesh S. Mehta
Publikováno v:
American Journal of Hematology. 98:712-719
Autor:
Jun Zou, Piyanuch Kongtim, Betül Oran, Samer A. Srour, Uri Greenbaum, Yudith Carmazzi, Gabriela Rondon, Stefan O. Ciurea, Qing Ma, Elizabeth J. Shpall, Richard E. Champlin, Kai Cao
Publikováno v:
Cancer. 129:1205-1216