Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Paul R. August"'
Autor:
Nadine Bakkar, Alexander Starr, Benjamin E. Rabichow, Ileana Lorenzini, Zachary T. McEachin, Robert Kraft, Matthew Chaung, Sam Macklin-Isquierdo, Taylor Wingfield, Briggs Carhart, Nathan Zahler, Wen-Hsuan Chang, Gary J. Bassell, Alexandre Betourne, Nicholas Boulis, Samuel V. Alworth, Justin K. Ichida, Paul R. August, Daniela C. Zarnescu, Rita Sattler, Robert Bowser
Publikováno v:
Neurobiology of Disease, Vol 149, Iss , Pp 105228- (2021)
Disruption in copper homeostasis causes a number of cognitive and motor deficits. Wilson's disease and Menkes disease are neurodevelopmental disorders resulting from mutations in the copper transporters ATP7A and ATP7B, with ATP7A mutations also caus
Externí odkaz:
https://doaj.org/article/9e65354b9c964af3a16790973ddace6f
Autor:
Jeffrey W. Santoso, Paul R August, Divya Gupta, Megan L. McCain, Nethika R. Ariyasinghe, Mark J. Pincus
Publikováno v:
Annals of Biomedical Engineering. 49:523-535
Many techniques for engineering and interrogating three-dimensional (3-D) muscle bundles from animal- or patient-derived myoblasts have recently been developed to overcome the limitations of existing in vitro and in vivo model systems. However, many
Autor:
Gabriel R. Linares, Justin K. Ichida, Yingxiao Shi, Brandon B Ge, Yichen Li, Jacob Komberg, R. Jeroen Pasterkamp, Davide Trotti, Valerie Hennes, Leonard H. van den Berg, Nicole Koutsodendris, Jason A. Chen, Kaitlin P. Sandor, Vamshidhar R. Vangoor, Louise Menendez, Amy R. Nelson, Michael E. Ward, Tze-Yuan Cheng, Yaoming Wang, Phillip E. Woolwine, Wen-Hsuan Chang, Ketharini Senthilkumar, Kim A. Staats, Mickey Huang, Carina Seah, Alice Zhang, Chris Grunseich, Esther Y. Son, Eric Hendricks, Michael J. Cowan, Paul R. August, Kassandra Kisler, Shih Jong J. Lee, Marcelo P. Coba, Shu Ting Hung, Shaoyu Lin, Brent Wilkinson, N. Wisniewski, Berislav V. Zlokovic, Tohru Sugawara, T. Grant Belgard, Victor Hanson-Smith, Xinmei Wen
Publikováno v:
Nature Medicine, 24(3), 313. Nature Publishing Group
An intronic GGGGCC repeat expansion in C9ORF72 is the most common cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), but the pathogenic mechanism of this repeat remains unclear. Using human induced motor neurons (iMNs), w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a7b18c3fd3677e0457e409e74f97ed0
https://dspace.library.uu.nl/handle/1874/364200
https://dspace.library.uu.nl/handle/1874/364200
Autor:
Su Wang, Denis Loyaux, Michael A. Smith, Catherine Déon, Jean-Claude Guillemot, Steven A. Goldman, Sébastien Roudières, Philippe Fabre, Paul R. August, Fréderique Guette, Pascual Ferrara, François Autelitano, Qinggong Ping, Romane Auvergne, Vasudeo Badarinarayana, Sridaran Natesan
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e110316 (2014)
PLoS ONE
PLoS ONE
Glioblastoma multiform (GBM) remains clinical indication with significant "unmet medical need". Innovative new therapy to eliminate residual tumor cells and prevent tumor recurrences is critically needed for this deadly disease. A major challenge of
Publikováno v:
Gene. 175:261-267
The mcr locus from Streptomyces lavendulae confers high level resistance (> 100 μg/ml) to mitomycin C (MC) and related mitomycins when cloned into Streptomyces lividans . Production of the mcrA gene product (MCRA) was shown to be MC-inducible by ide
Publikováno v:
Genomics. 79(4)
The ability to generate and obtain full-length (FL) cDNAs is of critical importance to the field of genomics. Most cDNAs in a traditional cDNA library lack the initiating 5' ATG, making it difficult to obtain a FL clone. We report here on an improved