Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Mong Heng Wang"'
Autor:
Liang-Huan Wu, Yu-Wen Cheng, Fan-Li Lin, Kai-Cheng Hsu, Mong-Heng Wang, Jing-Lun Yen, Tsung-Jen Wang, Tony Eight Lin, Yi-Chien Liu, Wei-Jan Huang, George Hsiao
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 174, Iss , Pp 116538- (2024)
Glaucoma is considered a neurodegenerative disease characterized by progressive visual field defects that may lead to blindness. Although controlling intraocular pressure (IOP) is the mainstay of glaucoma treatment, some glaucoma patients have unmet
Externí odkaz:
https://doaj.org/article/1f572671db9b44c28ad07161acd206b1
Autor:
Fan-Li Lin, Yu-Wen Cheng, Li-Huei Chen, Jau-Der Ho, Jing-Lun Yen, Mong-Heng Wang, Tzong-Huei Lee, George Hsiao
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 158, Iss , Pp 114138- (2023)
Age-related macular degeneration (AMD) is the leading cause of low vision and blindness for which there is currently no cure. Increased matrix metalloproteinase-9 (MMP-9) was found in AMD and potently contributes to its pathogenesis. Resident microgl
Externí odkaz:
https://doaj.org/article/1a14de4ff8cf4dd28bd8ce199fc224fa
Publikováno v:
Antioxidants, Vol 9, Iss 6, p 520 (2020)
Oxidative stress is an important factor to cause the pathogenesis of diabetic retinopathy (DR) because the retina has high vascularization and long-time light exposition. Cyclooxygenase (COX), lipoxygenase (LOX), and cytochrome P450 (CYP) enzymes can
Externí odkaz:
https://doaj.org/article/a2c3ad1cbadc4e648c393b17a3420ea9
Autor:
Jing-Shiun Jan, Chih-Hao Yang, Mong-Heng Wang, Fan-Li Lin, Jing-Lun Yen, Irene Hsieh, Maksim Khotimchenko, Tzong-Huei Lee, George Hsiao
Publikováno v:
Marine Drugs, Vol 17, Iss 6, p 360 (2019)
Activated human monocytes/macrophages, which increase the levels of matrix metalloproteinases (MMPs) and pro-inflammatory cytokines, are the essential mechanisms for the progression of sepsis. In the present study, we determined the functions and mec
Externí odkaz:
https://doaj.org/article/4052ed46e4f74ec1acd4c8034b42b4b4
Autor:
Luyun Wang, Yang Liu, Huamin Wang, Xun Liu, Jie Chen, Mong-Heng Wang, Jingfeng Wang, Hui Huang
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e94400 (2014)
Inner medulla collecting duct (IMCD) cells are the key part for urinary concentration. Hypotonic stress may trigger apoptosis of IMCD cells and induce renal injury. Epoxyeicosatrienoic acids (EETs) play an important role in anti-apoptosis, but their
Externí odkaz:
https://doaj.org/article/be5ccceacd454c2a9580207a24e58b69
Autor:
Khaled Elmasry, Amany Tawfik, Nader Sheibani, Khaled A. Hussein, Mong Heng Wang, Mohamed El-Shafey, Babak Baban, Ahmed Ibrahim, Mohamed Al-Shabrawey, Heba Saleh
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1862:636-645
Aims Our previous studies have established a role for 12/15-lipoxygenase (LO) in mediating the inflammatory response in diabetic retinopathy (DR). However, the extent at which the local or systemic induction of 12/15-LO activity involved is unclear.
Publikováno v:
European Journal of Pharmacology. 786:186-193
Both clinical and experimental studies have demonstrated that vascular calcification (VC) is a common pathology shared in many chronic diseases such as chronic kidney disease (CKD) and diabetes. It's an independent risk factor for cardiovascular even
Publikováno v:
Prostaglandins & Other Lipid Mediators. 125:80-89
Despite the optimization of blood glucose control and the therapeutic management of risk factors, obesity- and diabetes-induced cardiovascular diseases are still major health problems in the United States. Arachidonic acid (AA), an endogenous 20-carb
Publikováno v:
Prostaglandins & Other Lipid Mediators. 122:45-53
Arachidonic acid (AA) is metabolized by cyclooxygenase (COX) and cytochrome P450 (CYP) enzymes into eicosanoids, which are involved in cardiovascular diseases and stroke. Evidence has demonstrated the important functions of these eicosanoids in regul
Publikováno v:
Prostaglandins & other lipid mediators
Clinical studies have suggested that the renin-angiotensin system (RAS) may be a promising therapeutic target in treating diabetic retinopathy (DR). While AT1 receptor blockade decreased the incidence of DR in the DIRECT trial, it did not reduce the