Zobrazeno 1 - 10
of 175
pro vyhledávání: '"John C. Byrd"'
Autor:
Kellie J. Archer, Han Fu, Krzysztof Mrózek, Deedra Nicolet, Alice S. Mims, Geoffrey L. Uy, Wendy Stock, John C. Byrd, Wolfgang Hiddemann, Jan Braess, Karsten Spiekermann, Klaus H. Metzeler, Tobias Herold, Ann-Kathrin Eisfeld
Publikováno v:
Journal of Hematology & Oncology, Vol 17, Iss 1, Pp 1-5 (2024)
Abstract Patients with cytogenetically normal acute myeloid leukemia (CN-AML) may harbor prognostically relevant gene mutations and thus be categorized into one of the three 2022 European LeukemiaNet (ELN) genetic-risk groups. Nevertheless, there rem
Externí odkaz:
https://doaj.org/article/8f315fed381640c280c37db73db5c758
Autor:
Janani Ravikrishnan, Daisy Y. Diaz-Rohena, Elizabeth Muhowski, Xiaokui Mo, Tzung-Huei Lai, Shrilekha Misra, Charmelle D. Williams, John Sanchez, Andrew Mitchell, Suresh Satpati, Elizabeth Perry, Tierney Kaufman, Chaomei Liu, Arletta Lozanski, Gerard Lozanski, KerryA Rogers, Adam S. Kittai, Seema A. Bhat, Mary C. Collins, Matthew S. Davids, Nitin Jain, William G. Wierda, Rosa Lapalombella, John C. Byrd, Fenlai Tan, Yi Chen, Yu Chen, Yue Shen, Stephen P. Anthony, Jennifer A. Woyach, Deepa Sampath
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Patients with chronic lymphocytic leukemia (CLL) respond well to initial treatment with the Bcell lymphoma 2 (BCL2) inhibitor venetoclax. Upon relapse, they often retain sensitivity to BCL2 targeting, but durability of response remains a concern. We
Externí odkaz:
https://doaj.org/article/84739096159249b4b8f8ad48426936e4
Autor:
Giovanna Merchand-Reyes, Mikayla F. Bull, Ramasamy Santhanam, Maria L. Valencia-Pena, Rakesh A. Murugesan, Aadesh Chordia, Xiaokui-Molly Mo, Frank H. Robledo-Avila, Juan De Dios Ruiz-Rosado, William Edgar Carson, John C. Byrd, Jennifer A. Woyach, Susheela Tridandapani, Jonathan P. Butchar
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionTherapeutic antibodies have become a major strategy to treat oncologic diseases. For chronic lymphocytic leukemia, antibodies against CD20 are used to target and elicit cytotoxic responses against malignant B cells. However, efficacy is o
Externí odkaz:
https://doaj.org/article/2840c3664e3b44e69f5cbcfe156bc02d
Autor:
John C. Byrd, Jennifer L. Gatz, Cynthia Lim Louis, Alice S. Mims, Uma Borate, Ashley O. Yocum, Theophilus J. Gana, Amy Burd
Publikováno v:
Cancer Medicine, Vol 12, Iss 17, Pp 18368-18380 (2023)
Abstract Background We evaluated the frequency of genomic testing and treatment patterns by age category in patients with newly diagnosed (ND) acute myeloid leukemia (AML) treated in both academic‐ and community‐based health systems within a sing
Externí odkaz:
https://doaj.org/article/a3d13c3e8d844f3baf6026abc07719ab
Autor:
Zachary A. Hing, Janek S. Walker, Ethan C. Whipp, Lindsey Brinton, Matthew Cannon, Pu Zhang, Steven Sher, Casey B. Cempre, Fiona Brown, Porsha L. Smith, Claudio Agostinelli, Stefano A. Pileri, Jordan N. Skinner, Katie Williams, Hannah Phillips, Jami Shaffer, Larry P. Beaver, Alexander Pan, Kyle Shin, Charles T. Gregory, Gulcin H. Ozer, Selen A. Yilmaz, Bonnie K. Harrington, Amy M. Lehman, Lianbo Yu, Vincenzo Coppola, Pearlly Yan, Peggy Scherle, Min Wang, Philip Pitis, Chaoyi Xu, Kris Vaddi, Selina Chen-Kiang, Jennifer Woyach, James S. Blachly, Lapo Alinari, Yiping Yang, John C. Byrd, Robert A. Baiocchi, Bradley W. Blaser, Rosa Lapalombella
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Richter’s Transformation is a treatment-resistant and fatal progression from Chronic Lymphocytic Leukemia (CLL) to an aggressive lymphoma. Here, the authors show that PRMT5 is upregulated months prior to and after transformation, PRMT5 overexpressi
Externí odkaz:
https://doaj.org/article/69b4b26dffde485788921c4c7e1fc14a
Autor:
Sydney Fobare, Ola A. Elgamal, Mark Wunderlich, Emily Stahl, Abeera Mehmood, Casie Furby, James R. Lerma, Thomas M. Sesterhenn, Jianmin Pan, Jayesh Rai, Megan E. Johnstone, Amina Abdul-Aziz, Mariah L. Johnson, Shesh N. Rai, John C. Byrd, Erin Hertlein
Publikováno v:
Cancers, Vol 16, Iss 3, p 569 (2024)
Background: Acute myeloid leukemia (AML) is the malignant proliferation of immature myeloid cells characterized by a block in differentiation. As such, novel therapeutic strategies to promote the differentiation of immature myeloid cells have been su
Externí odkaz:
https://doaj.org/article/02f1d6d558f24461bc493ff6448ff7f7
Autor:
Alice Mims, Ying Huang, Eric Eisenmann, Shelley Orwick, Daelynn Buelow, Ronan Swords, Joshua Zeidner, Matthew Foster, Tara L. Lin, Maria Baer, Yazan Madanat, Tibor Kovacsovics, Robert Redner, Zeina Al-Mansour, Mona Stefanos, Molly Martycz, Franchesca Druggan, Timothy Chen, Ashley Yocum, Uma Borate, Brian Druker, Amy Burd, Ross Levine, Sharyn Baker, John C. Byrd
Publikováno v:
HemaSphere, Vol 7, p e2938119 (2023)
Externí odkaz:
https://doaj.org/article/50e9d0f998544b3ba4e36598c04e954d
Autor:
Jennifer Woyach, Ian W. Flinn, Farrukh Awan, Herbert Eradat, Danielle M. Brander, Michael Tees, Sameer Parikh, Tycel Phillips, Razi Ghori, Ima Paydar, Mohammed Z. H. Farooqui, John C. Byrd, Deborah Stephens
Publikováno v:
HemaSphere, Vol 7, p e7809236 (2023)
Externí odkaz:
https://doaj.org/article/69bf151243aa40aea67348ac1c9c5069
Autor:
John C. Byrd, Seema Ali Bhat, Farrukh Awan, Pratyush Giri, Sumita Ratnasingam, Roman Hájek, Dagmar Hess, Daniela Alves, Jan Maciej Zaucha, Annalise Shen, Elizabeth Bilotti, Jesse Mcgreivy, Wayne P. Rothbaum, Hanna Ciepluch
Publikováno v:
HemaSphere, Vol 7, p e197904a (2023)
Externí odkaz:
https://doaj.org/article/8da8cf41c62841f09bec7dcbf3d95b7f
Autor:
Elizabeth M. Muhowski, Janani Ravikrishnan, Britten Gordon, Lianbo Yu, Shrilekha Misra, Brandi Walker, Sudharshan Eathiraj, Deepa Sampath, Kerry A. Rogers, John C. Byrd, Jennifer A. Woyach
Publikováno v:
Journal of Hematology & Oncology, Vol 15, Iss 1, Pp 1-5 (2022)
Abstract Inhibitors of B cell receptor (BCR) signaling such as the Bruton’s tyrosine kinase (BTK) inhibitors are effective therapeutics for chronic lymphocytic leukemia (CLL). The first-in-class covalent BTK inhibitor, ibrutinib, produces durable r
Externí odkaz:
https://doaj.org/article/cbd3349984cb4091abe926011ab6ccf0