Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Jeanne Y. Domoradzki"'
Autor:
Felix M. Kluxen, Edgars Felkers, Steve McEuen, Philip Fisher, Christian Strupp, Christine Lorez, Jeanne Y. Domoradzki, Christiane Wiemann
Publikováno v:
Archives of toxicology. 96(9)
Dermal absorption values are used to translate external dermal exposure into potential systemic exposure for non-dietary risk assessment of pesticides. While the Environmental Protection Agency of the United States of America (US EPA) derives a commo
Autor:
Felix M, Kluxen, Styliani, Totti, Wilfred, Maas, Frank, Toner, Leanne, Page, Kathryn, Webbley, Rajendra, Nagane, Robert, Mingoia, Christine, Whitfield, John, Kendrick, Claire, Valentine, Jeanne Bernal, Dorange, Camille, Egron, Camille, Imart, Jeanne Y, Domoradzki, Philip, Fisher, Christine, Lorez, Steve, McEuen, Edgars, Felkers, Tao, Chen, Christiane, Wiemann
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 132
The dermal absorption potential of
Autor:
Felix M. Kluxen, Styliani Totti, Wilfred Maas, Frank Toner, Leanne Page, Kathryn Webbley, Rajendra Nagane, Robert Mingoia, Christine Whitfield, John Kendrick, Claire Valentine, Jeanne Bernal Dorange, Camille Egron, Camille Imart, Jeanne Y. Domoradzki, Philip Fisher, Christine Lorez, Steve McEuen, Edgars Felkers, Tao Chen, Christiane Wiemann
Publikováno v:
Regulatory Toxicology and Pharmacology. 133:105213
Autor:
Felix M. Kluxen, Styliani Totti, Wilfred Maas, Frank Toner, Leanne Page, Kathryn Webbley, Rajendra Nagane, Robert Mingoia, Christine Whitfield, John Kendrick, Claire Valentine, Jeanne Bernal Dorange, Camille Egron, Camille Imart, Jeanne Y. Domoradzki, Philip Fisher, Christine Lorez, Steve McEuen, Edgars Felkers, Tao Chen, Christiane Wiemann
Publikováno v:
Regulatory Toxicology and Pharmacology. 132:105184
Autor:
Tao Chen, C. Valentine, R. Mingoia, Stella Totti, P. Fisher, Jeanne Y. Domoradzki, E. Felkers, W. Maas, C. Imart, C. Whitfield, K. Webbley, C. Wiemann, S. McEuen, B. Darraji, Felix M. Kluxen, J. Kendrick, C. Egron, F. Toner, R. Parr-Dobrzanksi, R. Nagane, J.B. Dorange, C. Lorez, L. Page
Publikováno v:
Toxicology Letters. 350:S249-S250
Autor:
David J. Miller, James Nguyen, Harvey J. Clewell, Monique M. Perron, Rachel Brunner, Pankaj Gulati, Nicole Kleinstreuer, Rhian B. Cope, Anna Lowit, Alan R. Boobis, Jeffrey M. Minucci, Elizabeth Mendez, Jeffrey Dawson, Alicia Paini, Yu-Mei Tan, Kelly Lowe, Hua Qian, Philip Villanueva, Jeanne Y. Domoradzki, Michelle R. Embry, John F. Wambaugh, Katherine Phillips, Hugh A. Barton, Brandall Ingle, Tharacad S. Ramanarayanan, Fiona Sewell, Peter P. Egeghy
Publikováno v:
Regulatory Toxicology and Pharmacology. 127:105070
Top dose selection for repeated dose animal studies has generally focused on identification of apical endpoints, use of the limit dose, or determination of a maximum tolerated dose (MTD). The intention is to optimize the ability of toxicity tests per
Autor:
Jacob M. Sushynski, Debra A. McNett, Jeanne Y. Domoradzki, Kathleen P. Plotzke, Christopher M. Sushynski, Cynthia Van Landingham
Publikováno v:
Toxicology Letters. 279:98-114
Octamethylcyclotetrasiloxane (D4) and decamethylcyclopentasiloxane (D5) are low molecular weight cyclic volatile methyl siloxanes (cVMSs) primarily used as intermediates or monomers in the production of high molecular weight silicone polymers. The us
Autor:
Timothy L. Ross, Debra A. McNett, Jeanne Y. Domoradzki, Jacob M. Sushynski, Jeremy Durham, Timothy A. Springer, Lisa M. Thackery, Kent B. Woodburn
Publikováno v:
Toxicology Letters. 279:115-124
Critical factors (uptake, distribution, metabolism and elimination) for understanding the bioaccumulation/biomagnification potential of Octamethylcyclotetrasiloxane (D 4 ) and Decamethylcyclopentasiloxane (D 5 ) siloxanes in fish were investigated to
Autor:
Lynea Murphy, Robert T. Mingoia, Jeanne Y. Domoradzki, Claire Terry, Carrie R. Fleming, Sean C. Gehen, Michael J. Bartels
Publikováno v:
Regulatory Toxicology and Pharmacology. 117:104765
Autor:
Jeanne Y. Domoradzki, C. Eric Hack, Paul M. Hinderliter, Kota Hirasawa, Alicia Paini, Annie Lumen, Yu-Mei Tan, Jeremy A. Leonard, John F. Wambaugh, Fagen Zhang, Jeffrey W. Fisher, Michelle R. Embry, Amechi Chukwudebe, Melissa Chan, Patricia Ruiz, Hua Qian
Publikováno v:
Regulatory toxicology and pharmacology : RTP
Physiologically-based pharmacokinetic (PBPK) modeling analysis does not stand on its own for regulatory purposes but is a robust tool to support drug/chemical safety assessment. While the development of PBPK models have grown steadily since their eme