Zobrazeno 1 - 10
of 17
pro vyhledávání: '"David J. Douin"'
Autor:
David J. Douin, Adane F. Wogu, Laurel E. Beaty, Nichole E. Carlson, Tellen D. Bennett, Neil R. Aggarwal, David A. Mayer, Toan C. Ong, Seth Russell, Jeffrey Steele, Jennifer L. Peers, Kyle C. Molina, Matthew K. Wynia, Adit A. Ginde
Publikováno v:
BMC Infectious Diseases, Vol 22, Iss 1, Pp 1-10 (2022)
Abstract Background Neutralizing monoclonal antibodies (mAbs) are highly effective in reducing hospitalization and mortality among early symptomatic COVID-19 patients in clinical trials and real-world data. While resistance to some mAbs has since eme
Externí odkaz:
https://doaj.org/article/9243363dc9f34305a5f57b6c977b0775
Autor:
David J. Douin, MD, Jack Pattee, PhD, Benjamin Scott, MD, Ana Fernandez-Bustamante, MD, PhD, Meghan Prin, MD, MS, Tobias Eckle, MD, PhD, Adit A. Ginde, MD, MPH, Nathan Clendenen, MD, MS
Publikováno v:
Critical Care Explorations, Vol 5, Iss 3, p e0878 (2023)
OBJECTIVES:. The use of hyperoxemia during cardiac surgery remains controversial. We hypothesized that intraoperative hyperoxemia during cardiac surgery is associated with an increased risk of postoperative pulmonary complications. DESIGN:. Retrospec
Externí odkaz:
https://doaj.org/article/a2aa1c346d2c4e4bb99e06b2f698d811
Autor:
Layne Dylla, David J. Douin, Erin L. Anderson, John D. Rice, Conner L. Jackson, Vikhyat S. Bebarta, Christopher J. Lindsell, Alex C. Cheng, Steven G. Schauer, Adit A. Ginde
Publikováno v:
Trials, Vol 22, Iss 1, Pp 1-10 (2021)
Abstract Background Targeted normoxia (SpO2 90–96% or PaO2 60–100 mmHg) may help to conserve oxygen and improve outcomes in critically ill patients by avoiding potentially harmful hyperoxia. However, the role of normoxia for critically ill trauma
Externí odkaz:
https://doaj.org/article/25211e04f7374b8e967ab3d7ae5c2597
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
BackgroundAnimal studies have shown that midazolam can increase vulnerability to cardiac ischemia, potentially via circadian-mediated mechanisms. We hypothesized that perioperative midazolam administration is associated with an increased incidence of
Externí odkaz:
https://doaj.org/article/9dacd9d4242a4c71be938e6dfcf90c5b
Autor:
Ashwin Sunderraj, BS, Chloe Cho, Xuan Cai, MS, Shruti Gupta, MD, MPH, Rupal Mehta, MD, MSCI, Tamara Isakova, MD, MMSc, David E. Leaf, MD, MMSc, Anand Srivastava, MD, MPH, STOP-COVID Investigators, Carl P. Walther, Samaya J. Anumudu, Justin Arunthamakun, Kathleen F. Kopecky, Gregory P. Milligan, Peter A. McCullough, Thuy-Duyen Nguyen, Shahzad Shaefi, Megan L. Krajewski, Sidharth Shankar, Ameeka Pannu, Juan D. Valencia, Sushrut S. Waikar, Zoe A. Kibbelaar, Ambarish M. Athavale, Peter Hart, Shristi Upadhyay, Ishaan Vohra, Ajiboye Oyintayo, Adam Green, Jean-Sebastien Rachoin, Christa A. Schorr, Lisa Shea, Daniel L. Edmonston, Christopher L. Mosher, Alexandre M. Shehata, Zaza Cohen, Valerie Allusson, Gabriela Bambrick-Santoyo, Noor ul aain Bhatti, Bijal Mehta, Aquino Williams, Samantha K. Brenner, Patricia Walters, Ronaldo C. Go, Keith M. Rose, Miguel A. Hernán, Amy M. Zhou, Ethan C. Kim, Rebecca Lisk, Lili Chan, Kusum S. Mathews, Steven G. Coca, Deena R. Altman, Aparna Saha, Howard Soh, Huei Hsun Wen, Sonali Bose, Emily A. Leven, Jing G. Wang, Gohar Mosoyan, Girish N. Nadkarni, Pattharawin Pattharanitima, Emily J. Gallagher, Allon N. Friedman, John Guirguis, Rajat Kapoor, Christopher Meshberger, Katherine J. Kelly, Chirag R. Parikh, Brian T. Garibaldi, Celia P. Corona-Villalobos, Yumeng Wen, Steven Menez, Rubab F. Malik, Carmen Elena Cervantes, Samir C. Gautam, Mary C. Mallappallil, Jie Ouyang, Sabu John, Ernie Yap, Yohannes Melaku, Ibrahim Mohamed, Siddhartha Bajracharya, Isha Puri, Mariah Thaxton, Jyotsna Bhattacharya, John Wagner, Leon Boudourakis, H. Bryant Nguyen, Afshin Ahoubim, Leslie F. Thomas, Dheeraj Reddy Sirganagari, Pramod K. Guru, Kianoush Kashani, Shahrzad Tehranian, Yan Zhou, Paul A. Bergl, Jesus Rodriguez, Jatan A. Shah, Mrigank S. Gupta, Princy N. Kumar, Deepa G. Lazarous, Seble G. Kassaye, Michal L. Melamed, Tanya S. Johns, Ryan Mocerino, Kalyan Prudhvi, Denzel Zhu, Rebecca V. Levy, Yorg Azzi, Molly Fisher, Milagros Yunes, Kaltrina Sedaliu, Ladan Golestaneh, Maureen Brogan, Neelja Kumar, Michael Chang, Jyotsana Thakkar, Ritesh Raichoudhury, Akshay Athreya, Mohamed Farag, Edward J. Schenck, Soo Jung Cho, Maria Plataki, Sergio L. Alvarez-Mulett, Luis G. Gomez-Escobar, Di Pan, Stefi Lee, Jamuna Krishnan, William Whalen, David Charytan, Ashley Macina, Sobaata Chaudhry, Benjamin Wu, Frank Modersitzki, Anand Srivastava, Alexander S. Leidner, Carlos Martinez, Jacqueline M. Kruser, Richard G. Wunderink, Alexander J. Hodakowski, Juan Carlos Q. Velez, Eboni G. Price-Haywood, Luis A. Matute-Trochez, Anna E. Hasty, Muner MB. Mohamed, Rupali S. Avasare, David Zonies, David E. Leaf, Shruti Gupta, Meghan E. Sise, Erik T. Newman, Samah Abu Omar, Kapil K. Pokharel, Shreyak Sharma, Harkarandeep Singh, Simon Correa, Tanveer Shaukat, Omer Kamal, Wei Wang, Heather Yang, Jeffery O. Boateng, Meghan Lee, Ian A. Strohbehn, Jiahua Li, Ariel L. Mueller, Roberta E. Redfern, Nicholas S. Cairl, Gabriel Naimy, Abeer Abu-Saif, Danyell Hall, Laura Bickley, Chris Rowan, Farah Madhani-Lovely, Vivian S. Cruz, Kristen M. Hess, Alanna L. Jacobs, Vasil Peev, Jochen Reiser, John J. Byun, Andrew Vissing, Esha M. Kapania, Zoe Post, Nilam P. Patel, Joy-Marie Hermes, Anne K. Sutherland, Amee Patrawalla, Diana G. Finkel, Barbara A. Danek, Sowminya Arikapudi, Jeffrey M. Paer, Peter Cangialosi, Mark Liotta, Jared Radbel, Sonika Puri, Jag Sunderram, Matthew T. Scharf, Ayesha Ahmed, Ilya Berim, Jayanth S. Vatson, Shuchi Anand, Joseph E. Levitt, Pablo Garcia, Suzanne M. Boyle, Rui Song, Jingjing Zhang, Sang Hoon Woo, Xiaoying Deng, Goni Katz-Greenberg, Katharine Senter, Moh’d A. Sharshir, Vadym V. Rusnak, Muhammad Imran Ali, Anip Bansal, Amber S. Podoll, Michel Chonchol, Sunita Sharma, Ellen L. Burnham, David J. Douin, Arash Rashidi, Rana Hejal, Eric Judd, Laura Latta, Ashita Tolwani, Timothy E. Albertson, Jason Y. Adams, Steven Y. Chang, Rebecca M. Beutler, Carl E. Schulze, Etienne Macedo, Harin Rhee, Kathleen D. Liu, Vasantha K. Jotwani, Jay L. Koyner, Chintan V. Shah, Vishal Jaikaransingh, Stephanie M. Toth-Manikowski, Min J. Joo, James P. Lash, Javier A. Neyra, Nourhan Chaaban, Madona Elias, Yahya Ahmad, Alfredo Iardino, Elizabeth H. Au, Jill H. Sharma, Marie Anne Sosa, Sabrina Taldone, Gabriel Contreras, David De La Zerda, Hayley B. Gershengorn, Bhavarth Shukla, Alessia Fornoni, Tanira Ferreira, Salim S. Hayek, Pennelope Blakely, Hanna Berlin, Tariq U. Azam, Husam Shadid, Michael Pan, Patrick O’ Hayer, Chelsea Meloche, Rafey Feroze, Rayan Kaakati, Danny Perry, Abbas Bitar, Elizabeth Anderson, Kishan J. Padalia, John P. Donnelly, Andrew J. Admon, Jennifer E. Flythe, Matthew J. Tugman, Emily H. Chang, Brent R. Brown, Amanda K. Leonberg-Yoo, Ryan C. Spiardi, Todd A. Miano, Meaghan S. Roche, Charles R. Vasquez, Amar D. Bansal, Natalie C. Ernecoff, Sanjana Kapoor, Siddharth Verma, Huiwen Chen, Csaba P. Kovesdy, Miklos Z. Molnar, Ambreen Azhar, S. Susan Hedayati, Mridula V. Nadamuni, Shani Shastri, Duwayne L. Willett, Samuel A.P. Short, Amanda D. Renaghan, Kyle B. Enfield, Pavan K. Bhatraju, A. Bilal Malik, Matthew W. Semler, Anitha Vijayan, Christina Mariyam Joy, Tingting Li, Seth Goldberg, Patricia F. Kao, Greg L. Schumaker, Nitender Goyal, Anthony J. Faugno, Caroline M. Hsu, Asma Tariq, Leah Meyer, Ravi K. Kshirsagar, Daniel E. Weiner, Aju Jose, Marta Christov, Jennifer Griffiths, Sanjeev Gupta, Aromma Kapoor, Perry Wilson, Tanima Arora, Ugochukwu Ugwuowo
Publikováno v:
Critical Care Explorations, Vol 4, Iss 9, p e0755 (2022)
OBJECTIVES:. Older age is a key risk factor for adverse outcomes in critically ill patients with COVID-19. However, few studies have investigated whether preexisting comorbidities and acute physiologic ICU factors modify the association between age a
Externí odkaz:
https://doaj.org/article/420b393e916045088d61f48360c52a52
Autor:
Michael J. Ward, David J. Douin, Wu Gong, Adit A. Ginde, Catherine L. Hough, Matthew C. Exline, Mark W. Tenforde, William B. Stubblefield, Jay S. Steingrub, Matthew E. Prekker, Akram Khan, D. Clark Files, Kevin W. Gibbs, Todd W. Rice, Jonathan D. Casey, Daniel J. Henning, Jennifer G. Wilson, Samuel M. Brown, Manish M. Patel, Wesley H. Self, Christopher J. Lindsell, for the Influenza and Other Viruses in the Acutely Ill (IVY) Network
Publikováno v:
Journal of Clinical and Translational Science, Vol 6 (2022)
Early in the COVID-19 pandemic, the World Health Organization stressed the importance of daily clinical assessments of infected patients, yet current approaches frequently consider cross-sectional timepoints, cumulative summary measures, or time-to-e
Externí odkaz:
https://doaj.org/article/bf328a32babb4cb7ae3251c226492d65
Autor:
David J. Douin, MD, Erin L. Anderson, RN, Layne Dylla, MD, PhD, John D. Rice, PhD, Conner L. Jackson, MS, Franklin L. Wright, MD, Vikhyat S. Bebarta, MD, Steven G. Schauer, DO, MS, Adit A. Ginde, MD, MPH
Publikováno v:
Critical Care Explorations, Vol 3, Iss 5, p e0418 (2021)
OBJECTIVES:. Hyperoxia is common among critically ill patients and may increase morbidity and mortality. However, limited evidence exists for critically injured patients. The objective of this study was to determine the association between hyperoxia
Externí odkaz:
https://doaj.org/article/db5f0756bf7644f3b17193328321367f
Autor:
David J. Douin, MD, Michael J. Ward, MD, PhD, Christopher J. Lindsell, PhD, Michelle P. Howell, BSN, Catherine L. Hough, MD, MSc, Matthew C. Exline, MD, Michelle N. Gong, MD, Michael S. Aboodi, MD, Mark W. Tenforde, MD, PhD, Leora R. Feldstein, PhD, William B. Stubblefield, MD, Jay S. Steingrub, MD, Matthew E. Prekker, MD, MPH, Samuel M. Brown, MD, Ithan D. Peltan, MD, MSc, Akram Khan, MD, D. Clark Files, MD, Kevin W. Gibbs, MD, Todd W. Rice, MD, MSc, Jonathan D. Casey, MD, David N. Hager, MD, PhD, Nida Qadir, MD, Daniel J. Henning, MD, Jennifer G. Wilson, MD, MS, Manish M. Patel, MD, Wesley H. Self, MD, MPH, Adit A. Ginde, MD, MPH
Publikováno v:
Critical Care Explorations, Vol 3, Iss 3, p e0361 (2021)
Objectives:. Given finite ICU bed capacity, knowledge of ICU bed utilization during the coronavirus disease 2019 pandemic is critical to ensure future strategies for resource allocation and utilization. We sought to examine ICU census trends in relat
Externí odkaz:
https://doaj.org/article/bf8ae6c00d02432fa286bbb01b37959c
Association between procalcitonin levels and duration of mechanical ventilation in COVID-19 patients
Autor:
Martin Krause, David J. Douin, Timothy T. Tran, Ana Fernandez-Bustamante, Muhammad Aftab, Karsten Bartels, Wenbin Tan
Publikováno v:
PLoS ONE, Vol 15, Iss 9 (2020)
Background Patients diagnosed with COVID-19 frequently require mechanical ventilation. Knowledge of laboratory tests associated with the prolonged need for mechanical ventilation may guide resource allocation. We hypothesized that an elevated plasma
Externí odkaz:
https://doaj.org/article/081b578f878d4fd69b42ce914a7b798e
Autor:
Caitlin Turbyfill, Katherine Adams, Mark W. Tenforde, Nancy L. Murray, Manjusha Gaglani, Adit A. Ginde, Tresa McNeal, Shekhar Ghamande, David J. Douin, H. Keipp Talbot, Jonathan D. Casey, Nicholas M. Mohr, Anne Zepeski, Nathan I. Shapiro, Kevin W. Gibbs, D. Clark Files, David N. Hager, Arber Shehu, Matthew E. Prekker, Anne E. Frosch, Matthew C. Exline, Michelle N. Gong, Amira Mohamed, Nicholas J. Johnson, Vasisht Srinivasan, Jay S. Steingrub, Ithan D. Peltan, Samuel M. Brown, Emily T. Martin, Adam S. Lauring, Akram Khan, Laurence W. Busse, Caitlin C. ten Lohuis, Abhijit Duggal, Jennifer G. Wilson, Alexandra June Gordon, Nida Qadir, Steven Y. Chang, Christopher Mallow, Carolina Rivas, Jennie H. Kwon, Natasha Halasa, James D. Chappell, Carlos G. Grijalva, Todd W. Rice, William B. Stubblefield, Adrienne Baughman, Jillian P. Rhoads, Christopher J. Lindsell, Kimberly W. Hart, Meredith McMorrow, Diya Surie, Wesley H. Self, Manish M. Patel
Publikováno v:
Vaccine, vol 40, iss 48
BackgroundTest-negative design (TND) studies have produced validated estimates of vaccine effectiveness (VE) for influenza vaccine studies. However, syndrome-negative controls have been proposed for differentiating bias and true estimates in VE evalu