Zobrazeno 1 - 10
of 43
pro vyhledávání: '"David C. Yeomans"'
Autor:
David C. Yeomans, Leah R. Hanson, Dean S. Carson, Brendan J. Tunstall, Mary R. Lee, Alexander Z. Tzabazis, Daniel Jacobs, William H. Frey
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract There is evidence of the therapeutic potential of intranasal oxytocin for the treatment of pain and various psychiatric disorders, however, there is scant evidence that oxytocin reaches the brain. We quantified the concentration and distribu
Externí odkaz:
https://doaj.org/article/941b748b10d24d72a4c41802e25eb95e
Autor:
Vimala N. Bharadwaj, Justin Meyerowitz, Bende Zou, Michael Klukinov, Ni Yan, Kaustubh Sharma, David J. Clark, Xinmin Xie, David C. Yeomans
Publikováno v:
Pharmaceutics, Vol 14, Iss 5, p 1105 (2022)
Background and Purpose: The intranasal administration of oxytocin (OT) reduces migraine headaches through activation of the oxytocin receptor (OTR). Magnesium ion (Mg2+) concentration is critical to the activation of the OTR, and a low serum Mg2+ con
Externí odkaz:
https://doaj.org/article/95a47f4b5c2b429583c60fd5b554ed48
Autor:
Vimala N. Bharadwaj, Alexander Z. Tzabazis, Michael Klukinov, Neil A. Manering, David C. Yeomans
Publikováno v:
Pharmaceutics, Vol 13, Iss 7, p 1088 (2021)
Pain, particularly chronic pain, remains one of the most debilitating and difficult-to-treat conditions in medicine. Chronic pain is difficult to treat, in part because it is associated with plastic changes in the peripheral and central nervous syste
Externí odkaz:
https://doaj.org/article/83e5994679b44d1a8eed5b72775cfdf1
Autor:
De-Yong Liang, Peyman Sahbaie, Yuan Sun, Karen-Amanda Irvine, Xiaoyou Shi, Anders Meidahl, Peng Liu, Tian-Zhi Guo, David C. Yeomans, J. David Clark
Publikováno v:
IBRO Reports, Vol 2, Iss C, Pp 14-23 (2017)
Chronic pain after traumatic brain injury (TBI) is very common, but the mechanisms linking TBI to pain and the pain-related interactions of TBI with peripheral injuries are poorly understood. In these studies we pursued the hypothesis that TBI pain s
Externí odkaz:
https://doaj.org/article/79217afe64ec488693660395cf4b7b7d
Autor:
Hyeon Jeong Lee, David C. Yeomans
Publikováno v:
Korean Journal of Anesthesiology, Vol 67, Iss 5, Pp 299-304 (2014)
Pain is difficult to investigate and difficult to treat, in part, because of problems in quantification and assessment. The use of opioids, combined with classic anesthetics to maintain hemodynamic stability by controlling responses to intraoperative
Externí odkaz:
https://doaj.org/article/6ee78e60fdbc4ac784c13a164253ca89
Autor:
Shashidhar Kori, Stephen D. Silberstein, Robert Cowan, Frank Porreca, Vimala N. Bharadwaj, David C. Yeomans
Publikováno v:
Headache: The Journal of Head and Face Pain. 61:1051-1059
Objective To highlight the emerging understanding of oxytocin (OT) and oxytocin receptors (OTRs) in modulating menstrual-related migraine (MRM). Background MRM is highly debilitating and less responsive to therapy, and attacks are of longer duration
Publikováno v:
Biomedical Signal Processing and Control. 40:220-225
Background Wavelet transform based analysis of heart rate variability is increasingly being used for a wide variety of clinical applications. There is no gold standard as to which wavelet to use and the correlation between results obtained by using d
Autor:
Michael Klukinov, Neil A. Manering, Vimala N. Bharadwaj, David C. Yeomans, Alexander Tzabazis
Publikováno v:
Pharmaceutics, Vol 13, Iss 1088, p 1088 (2021)
Pharmaceutics
Pharmaceutics
Pain, particularly chronic pain, remains one of the most debilitating and difficult-to-treat conditions in medicine. Chronic pain is difficult to treat, in part because it is associated with plastic changes in the peripheral and central nervous syste
Autor:
William H. Frey, Dean S. Carson, Jason M. Cuellar, Neil A. Manering, Daniel I. Jacobs, Michael Klukinov, Martin S. Angst, Yanli Qiao, Alexander Tzabazis, Allon Jacobs, James E. Miller, Conrado Pascual, Jordan Mechanic, David C. Yeomans
Publikováno v:
Cephalalgia. 36:943-950
Aims Our studies investigated the location of oxytocin receptors in the peripheral trigeminal sensory system and determined their role in trigeminal pain. Methods Oxytocin receptor expression and co-localization with calcitonin gene-related peptide w
Autor:
Michael Klukinov, Alexander Tzabazis, Longhui Cao, David C. Yeomans, Andreas Eisenried, Anders Christian Meidahl
Publikováno v:
Headache. 58(4)
Background Approximately 1.7 million Americans sustain a traumatic brain injury (TBI) each year and chronic pain is a common complication. Objective We studied the effects of intranasally administered oxytocin as a potential treatment for chronic pai