Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Boyoun Park"'
Autor:
Sujin Kang, Jaekyung Kim, Areum Park, Minsoo Koh, Wonji Shin, Gayoung Park, Taeyun A. Lee, Hyung Jin Kim, Heonjong Han, Yongbo Kim, Myung Kyung Choi, Jae Hyung Park, Eunhye Lee, Hyun-Soo Cho, Hyun Woo Park, Jae Hee Cheon, Sungwook Lee, Boyoun Park
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
The cortical actin cytoskeleton plays a role in maintaining intestinal epithelial integrity. Here the authors report that TRIM40, an E3 ligase, disrupts cortical actin formation and leads to loss of epithelial barrier integrity, and that genetic loss
Externí odkaz:
https://doaj.org/article/e495a621697c4ddeaf523b2d5d69b052
Autor:
Taeyun A. Lee, Heonjong Han, Ahsan Polash, Seok Keun Cho, Ji Won Lee, Eun A. Ra, Eunhye Lee, Areum Park, Sujin Kang, Junhee L. Choi, Ji Hyun Kim, Ji Eun Lee, Kyung-Won Min, Seong Wook Yang, Markus Hafner, Insuk Lee, Je-Hyun Yoon, Sungwook Lee, Boyoun Park
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
The nucleolus is the traditional site for ribosomal RNA biogenesis. Here, the authors find that the nucleolus is a site of inflammatory pre-mRNA turnover and elucidated how immune homeostasis can be maintained by controlling inflammatory gene express
Externí odkaz:
https://doaj.org/article/3900adf1879d4f5d8d92fd2ebe8a5501
Autor:
Areum Park, Eun A. Ra, Taeyun A. Lee, Hyun jin Choi, Eunhye Lee, Sujin Kang, Jun-Young Seo, Sungwook Lee, Boyoun Park
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Human cytomegalovirus (HCMV) has evolved several mechanisms to evade the host immune response. Here, Park et al. show that HCMV-encoded US7 and US8 proteins bind TLR3 and TLR4 and facilitate TLR degradation by distinct mechanisms, including ER-associ
Externí odkaz:
https://doaj.org/article/95f0e0a3d5bc417b873a6782f779185b
Autor:
Junghwa Seo, Yun Soo Park, Tae Hyun Kweon, Jingu Kang, Seongjin Son, Han Byeol Kim, Yu Ri Seo, Min Jueng Kang, Eugene C. Yi, Yong-ho Lee, Jin-Hong Kim, Boyoun Park, Won Ho Yang, Jin Won Cho
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
Post-translational modifications, including O-GlcNAcylation, play fundamental roles in modulating cellular events, including transcription, signal transduction, and immune signaling. Several molecular targets of O-GlcNAcylation associated with pathog
Externí odkaz:
https://doaj.org/article/4cefaf50d66a43bfb721459b71ae9d16
Autor:
Hyun jin Choi, Areum Park, Sujin Kang, Eunhye Lee, Taeyun A. Lee, Eun A. Ra, Jiseon Lee, Sungwook Lee, Boyoun Park
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
MAVS and STING signaling are central to interferon-inducing antiviral immunity. Here, the authors show how the human cytomegalovirus protein US9 can evade this immunity by antagonizing these pathways.
Externí odkaz:
https://doaj.org/article/5acb7a2aec44465ea086d375e55ecd0a
Autor:
Eun A. Ra, Taeyun A. Lee, Seung Won Kim, Areum Park, Hyun jin Choi, Insook Jang, Sujin Kang, Jae Hee Cheon, Jin Won Cho, Ji Eun Lee, Sungwook Lee, Boyoun Park
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
While non-canonical, Atg5/Atg7-independent autophagy has been reported to occur, molecular details of alternative autophagy pathways remain unknown. Here, the authors report that the protein TRIM31 mediates alternative autophagy in intestinal cells,
Externí odkaz:
https://doaj.org/article/105465ca7a7148d1ab2b63fadbbbcb8b
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e112754 (2014)
Cytokine production is essential for innate and adaptive immunity against microbial invaders and must be tightly controlled. Cytokine messenger RNA (mRNA) is in constant flux between the nucleus and the cytoplasm and in transcription, splicing, or de
Externí odkaz:
https://doaj.org/article/eeb9f18ec4eb4fc8b1549324ef1c85cb
Autor:
Youngkyun Kim, Boyoun Park, Sunglim Cho, Jinwook Shin, Kwangmin Cho, Youngsoo Jun, Kwangseog Ahn
Publikováno v:
PLoS Pathogens, Vol 4, Iss 8, p e1000123 (2008)
Human cytomegalovirus (HCMV) US6 glycoprotein inhibits TAP function, resulting in down-regulation of MHC class I molecules at the cell surface. Cells lacking MHC class I molecules are susceptible to NK cell lysis. HCMV expresses UL18, a MHC class I h
Externí odkaz:
https://doaj.org/article/da86eae1c511496b9e9551c691cf1784
Publikováno v:
Biochemical and Biophysical Research Communications. 654:94-101
Publikováno v:
Molecular carcinogenesis. 58(8)
Cellular nucleic acid-binding protein (CNBP) is associated with cell proliferation, and its expression is elevated in human tumors, but the molecular mechanisms of CNBP in tumor cell biology have not been fully elucidated. In this study, we report th