Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Armelle Bohineust"'
Integration of intermittent calcium signals in T cells revealed by temporally patterned optogenetics
Autor:
Béatrice Corre, Yassine El Janati Elidrissi, Justine Duval, Mailys Quilhot, Gaëtan Lefebvre, Solène Ecomard, Fabrice Lemaître, Zacarias Garcia, Armelle Bohineust, Erica Russo, Philippe Bousso
Publikováno v:
iScience, Vol 26, Iss 2, Pp 106068- (2023)
Summary: T cells become activated following one or multiple contacts with antigen-presenting cells. Calcium influx is a key signaling event elicited during these cellular interactions; however, it is unclear whether T cells recall and integrate calci
Externí odkaz:
https://doaj.org/article/129b59cdef164681884d2a17a20e5701
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
The ability to manipulate and monitor calcium signaling in cells in vivo would provide insights into signaling in an endogenous context. Here the authors develop a two-photon-responsive calcium actuator and reporter combination to monitor the effect
Externí odkaz:
https://doaj.org/article/fb7b30514bec4ff1a467119ddb06597e
Autor:
Lionel Le Bourhis, Mathilde Dusseaux, Armelle Bohineust, Stéphanie Bessoles, Emmanuel Martin, Virginie Premel, Maxime Coré, David Sleurs, Nacer-Eddine Serriari, Emmanuel Treiner, Claire Hivroz, Philippe Sansonetti, Marie-Lise Gougeon, Claire Soudais, Olivier Lantz
Publikováno v:
PLoS Pathogens, Vol 9, Iss 10, p e1003681 (2013)
Mucosal associated invariant T cells (MAIT) are innate T lymphocytes that detect a large variety of bacteria and yeasts. This recognition depends on the detection of microbial compounds presented by the evolutionarily conserved major-histocompatibili
Externí odkaz:
https://doaj.org/article/7bd53988a4ac4006b76003a1105be09d
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e19680 (2011)
T cells are major players of adaptive immune response in mammals. Recognition of an antigenic peptide in association with the major histocompatibility complex at the surface of an antigen presenting cell (APC) is a specific and sensitive process whos
Externí odkaz:
https://doaj.org/article/de40cee34ee64cf6af8b9ea27963b453
Autor:
Jacek Majewski, Marielle E. van Gijn, Alain Fischer, Geneviève de Saint Basile, Capucine Picard, Nada Jabado, Els Verhoeyen, Sonia Luce, Tayebeh Soheili, Nathalie Lambert, Amandine Durand, Armelle Bohineust, Claire Hivroz, Virginie Gandemer, Farid Ouchani, Chantal Brouzes, Catherine Heijmans, Anne Durandy, Isabelle Pic, Myriam Chouteau, Marina Cavazzana, Virgil A. S. H. Dalm, Nizar Mahlaoui, Aude Magerus-Chatinet, François-Loïc Cosset, Isabelle André-Schmutz, Delphine Monnier, Sven Kracker, Chantal Lagresle-Peyrou, Jean-Louis Stephan, Frédéric Rieux-Laucat, Hanem Sadek
Publikováno v:
Journal of Allergy and Clinical Immunology, 138(6), 1681–1689.e8. Mosby Inc.
Journal of Allergy and Clinical Immunology
Journal of Allergy and Clinical Immunology, Elsevier, 2016, 138 (6), pp.1681-1689.e8. ⟨10.1016/j.jaci.2016.04.032⟩
Journal of Allergy and Clinical Immunology, 2016, 138 (6), pp.1681-1689.e8. ⟨10.1016/j.jaci.2016.04.032⟩
Journal of Allergy and Clinical Immunology, Elsevier, 2016, 138 (6), pp.1681-1689.e8. 〈10.1016/j.jaci.2016.04.032〉
Journal of Allergy and Clinical Immunology, 138(6), 1681-+. Mosby Inc.
Journal of Allergy and Clinical Immunology
Journal of Allergy and Clinical Immunology, Elsevier, 2016, 138 (6), pp.1681-1689.e8. ⟨10.1016/j.jaci.2016.04.032⟩
Journal of Allergy and Clinical Immunology, 2016, 138 (6), pp.1681-1689.e8. ⟨10.1016/j.jaci.2016.04.032⟩
Journal of Allergy and Clinical Immunology, Elsevier, 2016, 138 (6), pp.1681-1689.e8. 〈10.1016/j.jaci.2016.04.032〉
Journal of Allergy and Clinical Immunology, 138(6), 1681-+. Mosby Inc.
International audience; BACKGROUND: We investigated 7 male patients (from 5 different families) presenting with profound lymphopenia, hypogammaglobulinemia, fluctuating monocytopenia and neutropenia, a poor immune response to vaccine antigens, and in
Autor:
Stéphanie Dogniaux, Claire Hivroz, Lydia Danglot, Jean-Marie Carpier, Karine Chemin, Katharina Gaus, Paola Larghi, Armelle Bohineust, Thierry Galli, David Williamson
Publikováno v:
Nature immunology. 14(7)
The mechanisms by which Lat (a key adaptor in the T cell antigen receptor (TCR) signaling pathway) and the TCR come together after TCR triggering are not well understood. We investigate here the role of SNARE proteins, which are part of protein compl