Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Anil Pahuja"'
Autor:
Arjun Khunger, Ghanashyam Sarikonda, Jennifer Tsau, Anil Pahuja, Zeni Alfonso, Jane Gao, Christian Laing, Christine Vaupel, Naveen Dakappagari, Ahmad A. Tarhini
Publikováno v:
Translational Oncology, Vol 14, Iss 3, Pp 101014- (2021)
Neoadjuvant therapy with ipilimumab in combination with high dose IFNα was evaluated in patients with locally/regionally advanced melanoma in a previously reported clinical trial [NCT01608594]. In this study, peripheral immune cell profiling was per
Externí odkaz:
https://doaj.org/article/099a2088a9b64bcebb0642fdaabb7971
Autor:
Reinhold Pollner, Ghanashyam Sarikonda, Kevin Nguyen, Anil Pahuja, Creton Kalfoglou, Kerri Burns, Naveen Dakappagari, Irene L. Ch’en, Shabnam Tangri
Publikováno v:
Cytometry Part B: Clinical Cytometry. 100:72-78
Exceptional clinical responses produced by the first chimeric antigen receptor T [CAR-T] cell therapies, and their entry into commercial markets prompted a logarithmic increase in the number of next generation CAR-T clinical trials. As a result, ther
Autor:
Paul C Trampont, Ghanashyam Sarikonda, Virginia Litwin, Laïla-Aïcha Hanafi, Vilma Decman, Anil Pahuja, Yongliang S Sun, Mélissa Mathieu, Michael Nathan Hedrick, Susan Reynolds, Steven Eck, Qiong Xue, Naveen Dakappagari, Jennifer J. Stewart, Shabnam Tangri, Mahwish Natalia, Piotr L Pierog
Publikováno v:
Cytometry. Part B, Clinical cytometryREFERENCES. 100(1)
Chimeric Antigen Receptor (CAR) T cells are recognized as efficacious therapies with demonstrated ability to produce durable responses in blood cancer patients. Regulatory approvals and acceptance of these unique therapies by patients and reimburseme
Publikováno v:
Autoimmunity. 45:310-319
Tregs play an important role in controlling immune responses, particularly autoimmunity. In NOD mouse model, an excellent model for autoimmune diabetes, transfer of Tregs was shown to prevent diabetes, whereas depletion of Tregs in vivo enhanced dise
Autor:
Peter Hevezi, Sandra M. Lechner, Anil Pahuja, A. Chen, Richard B. Roth, David G. Alleva, Albert Zlotnik, Gail M. Verge, Richard A. Maki
Publikováno v:
Scandinavian Journal of Immunology. 64:361-369
CC chemokine receptor 7 (CCR7) is involved in the initiation of immune responses by mediating the migration of naive T cells and mature dendritic cells to T-cell-rich zones of secondary lymphoid organs where antigen presen- tation occurs. To address
Autor:
Anil Pahuja, Thomas R. Ott, Warren Wade, Molly M. Gross, Sarah Hudson, Francisco M. Lio, David G. Alleva, Pedro B. Simpson, R. Scott Struthers, Monica S. Mistry
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 51:105-114
Introduction: Higher-throughput chemotaxis assays have had limited use in chemokine receptor pharmacology studies mainly because of the unavailability of optimal assay formats in addition to an incompatibility of chemotactic cell backgrounds with oth
Publikováno v:
Journal of Neuroimmunology. 112:97-105
EAE is a demyelinating disease which serves as an animal model for multiple sclerosis (MS). Myeloperoxidase (MPO) has been implicated in MS through its presence in invading macrophages, and by association of a -463G/A promoter polymorphism with incre
Autor:
Amitabh Gaur, Derek T. Chalmers, Paul J. Conlon, Nicholas Ling, Anil Pahuja, Paul D. Crowe, Lawrence Steinman, Stefen A. Boehme, Stefan Brocke
Publikováno v:
Journal of Neuroimmunology. 74:149-158
T-cells specific for a region of human myelin basic protein, amino acids 87-99 (hMBP87-99), have been implicated in the development of multiple sclerosis (MS) a demyelinating disease of the central nervous system. Administration of soluble altered pe
Autor:
Amitabh Gaur, Paul D. Crowe, Anil Pahuja, Nick Ling, Errol B. De Souza, Xin-Jun Liu, Stefen A. Boehme, Wylie Vale, Paul J. Conlon, Susan Tamraz, Tim Wong
Publikováno v:
Cellular Immunology. 176:103-112
Stress elicits a wide range of physiological changes involving the nervous, endocrine, and immune systems. Corticotropin-releasing factor (CRF) plays a key role in orchestrating this response, activating both the sympathetic nervous system and the hy
Publikováno v:
Transplant immunology. 23(1-2)
Background The major obstacle faced by patients with type 1 diabetes who undergo islet transplantation is a gradual decline in insulin independence. This decline may reflect alloimmune rejection, autoimmune recurrence and toxicity of drugs such as ra