Zobrazeno 1 - 10
of 1 328
pro vyhledávání: '"Alzheimer's Disease Neuroimaging Initiative"'
Autor:
Jing Tian, Kun Jia, Tienju Wang, Lan Guo, Zhenyu Xuan, Elias K. Michaelis, Russell H. Swerdlow, Alzheimer’s Disease Neuroimaging Initiative, Heng Du
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract The etiopathogenesis of late-onset Alzheimer’s disease (AD) is increasingly recognized as the result of the combination of the aging process, toxic proteins, brain dysmetabolism, and genetic risks. Although the role of mitochondrial dysfun
Externí odkaz:
https://doaj.org/article/a34bda56f50e4eb085e3cf1b8b00de17
Publikováno v:
Brain Informatics, Vol 11, Iss 1, Pp 1-18 (2024)
Abstract This study investigates the correlation between brain age and chronological age in healthy individuals using brain MRI images, aiming to identify potential biomarkers for neurodegenerative diseases like Alzheimer's. To achieve this, a novel
Externí odkaz:
https://doaj.org/article/3c8594f727c24604a02a480b8ee319da
Autor:
Andrew A Chen, Kelly Clark, Blake E Dewey, Anna DuVal, Nicole Pellegrini, Govind Nair, Youmna Jalkh, Samar Khalil, Jon Zurawski, Peter A Calabresi, Daniel S Reich, Rohit Bakshi, Haochang Shou, Russell T Shinohara, Alzheimer’s Disease Neuroimaging Initiative, and North American Imaging in Multiple Sclerosis Cooperative
Publikováno v:
PLoS Computational Biology, Vol 20, Iss 7, p e1012241 (2024)
Dimension reduction tools preserving similarity and graph structure such as t-SNE and UMAP can capture complex biological patterns in high-dimensional data. However, these tools typically are not designed to separate effects of interest from unwanted
Externí odkaz:
https://doaj.org/article/6dc81d154df04a90a16c0ae4b80ffc44
Autor:
Kaida Ning, Pascale B. Cannon, Jiawei Yu, Srinesh Shenoi, Lu Wang, Alzheimer’s Disease Neuroimaging Initiative, Joydeep Sarkar
Publikováno v:
Brain Informatics, Vol 11, Iss 1, Pp 1-11 (2024)
Abstract Different aspects of cognitive functions are affected in patients with Alzheimer’s disease. To date, little is known about the associations between features from brain-imaging and individual Alzheimer’s disease (AD)-related cognitive fun
Externí odkaz:
https://doaj.org/article/3b377b4ae953401188fc612ea52141a5
Autor:
Tianlu Chen, Lu Wang, Guoxiang Xie, Bruce S. Kristal, Xiaojiao Zheng, Tao Sun, Matthias Arnold, Gregory Louie, Mengci Li, Lirong Wu, Siamak Mahmoudiandehkordi, Matthew J. Sniatynski, Kamil Borkowski, Qihao Guo, Junliang Kuang, Jieyi Wang, Kwangsik Nho, Zhenxing Ren, Alexandra Kueider‐Paisley, Colette Blach, Rima Kaddurah‐Daouk, Wei Jia, Alzheimer's Disease Neuroimaging Initiative (ADNI) and the Alzheimer Disease Metabolomics Consortium (ADMC)
Publikováno v:
Advanced Science, Vol 11, Iss 9, Pp n/a-n/a (2024)
Abstract Sex disparities in serum bile acid (BA) levels and Alzheimer's disease (AD) prevalence have been established. However, the precise link between changes in serum BAs and AD development remains elusive. Here, authors quantitatively determined
Externí odkaz:
https://doaj.org/article/3a89ae1b680643a2b8379874f09be9e7
Autor:
Yutong Wang, Peiyang Gao, Hongman Liu, Tingyu Wang, Jiaming Fan, Tingbo Jiang, Alzheimer's Disease Neuroimaging Initiative (ADNI), Xiangxiang Pan, Peifang Wei
Publikováno v:
Chinese Medical Journal, Vol 137, Iss 1, Pp 117-119 (2024)
Externí odkaz:
https://doaj.org/article/ef4df2bf81a14a3788d6a704d5fb4773
Autor:
Xiao-He Hou, John Suckling, Xue-Ning Shen, Yong Liu, Chuan-Tao Zuo, Yu-Yuan Huang, Hong-Qi Li, Hui-Fu Wang, Chen-Chen Tan, Mei Cui, Qiang Dong, Lan Tan, Jin-Tai Yu, Alzheimer’s Disease Neuroimaging Initiative
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-12 (2023)
Abstract Background Early prevention of Alzheimer’s disease (AD) is a feasible way to delay AD onset and progression. Information on AD prediction at the individual patient level will be useful in AD prevention. In this study, we aim to develop ris
Externí odkaz:
https://doaj.org/article/29e263d09a744ddca09eb5252a873c92
Publikováno v:
PLoS ONE, Vol 19, Iss 5, p e0303278 (2024)
Currently, numerous studies focus on employing fMRI-based deep neural networks to diagnose neurological disorders such as Alzheimer's Disease (AD), yet only a handful have provided results regarding explainability. We address this gap by applying sev
Externí odkaz:
https://doaj.org/article/1ff03ef57ca849cfab3b6b16fabc8132
Autor:
Colleen Lacey, Theone Paterson, Jodie R Gawryluk, Alzheimer’s Disease Neuroimaging Initiative
Publikováno v:
PLoS ONE, Vol 19, Iss 4, p e0292576 (2024)
BackgroundThe Apolipoprotein E (APOE) gene has been established in the Alzheimer's disease (AD) literature to impact brain structure and function and may also show congruent effects in healthy older adults, although findings in this population are mu
Externí odkaz:
https://doaj.org/article/189705fd846141acbe2a4630fa5a0481
Publikováno v:
PLoS ONE, Vol 19, Iss 2, p e0296738 (2024)
We aimed to examine the potential effect of sex on the longitudinal association of baseline serum uric acid levels with brain amyloid accumulation over time among older adults with and without abnormal amyloid. At baseline, the study sample comprised
Externí odkaz:
https://doaj.org/article/4dc52df7035a44fc983e4c4769dffcb6